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Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Influence of Fiber Orientation on Mechanical Response of Jute Fiber-Reinforced Polymer Composites. [PDF]

open access: yesPolymers (Basel)
Iquilio R   +5 more
europepmc   +1 more source
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Mechanisms of the placebo response

Pulmonary Pharmacology & Therapeutics, 2013
The concept of placebo response has evolved in the past few years from the clinical trial setting and medical practice to a psychobiological model that gives us important information on how the patient's brain is modified by the psychosocial context around the therapy.
BENEDETTI, Fabrizio, AMANZIO, Martina
openaire   +3 more sources

Mechanisms of the inflammatory response

Best Practice & Research Clinical Anaesthesiology, 2004
The physiological alterations induced by acute inflammation present significant management challenges for anaesthesiologists. Major surgery, trauma, burns and sepsis all have large inflammatory components. Acute inflammation is characterized by vasodilatation, fluid exudation and neutrophil infiltration. These processes are activated and amplified by a
Edward R, Sherwood   +1 more
openaire   +2 more sources

Mechanically responsive crystalline materials

CrystEngComm, 2021
Guest editors Changquan Calvin Sun and C. Malla Reddy introduce the CrystEngComm themed issue on ‘Mechanically responsive crystalline materials’.
Changquan Calvin Sun, C. Malla Reddy
openaire   +1 more source

Fibroblast responses to mechanical forces

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 1998
The repair and maintenance of connective tissues is performed predominately by a mesenchymal cell known as a fibroblast. The activity of this cell is regulated, in part, by changes in the mechanical environment in which it resides. The authors have addressed some of the questions related to the fibroblast and how it responds to mechanical stimulation.
Eastwood, M.   +2 more
openaire   +3 more sources

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