Results 51 to 60 of about 5,284,833 (331)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Hilbert-Twin – A Novel Hilbert Transform-Based Method To Compute Envelope Of Free Decaying Oscillations Embedded In Noise, And The Logarithmic Decrement In High-Resolution Mechanical Spectroscopy HRMS

open access: yesArchives of Metallurgy and Materials, 2015
In this work, we present a novel Hilbert-twin method to compute an envelope and the logarithmic decrement, δ, from exponentially damped time-invariant harmonic strain signals embedded in noise.
Magalas L.B., Majewski M.
doaj   +1 more source

Alternative dynamic torsion test to evaluate the elastic modulus of polymers

open access: yesMaterials Research Express, 2020
This work presents an alternative for the determination of the torsion modulus, G, of polymers. These materials may be subjected to shear stresses in some structural applications; thereby, the knowledge of G is of great interest.
Lucas Pereira Piedade   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Low-Frequency Mechanical Spectroscopy of Lanthanum Cobaltite Based Mixed Conducting Oxides

open access: yesArchives of Metallurgy and Materials, 2016
The low-frequency mechanical spectra of lanthanum cobaltite based mixed conducting oxides have been measured using a computer-controlled inverted torsion pendulum. The results indicate that the internal friction spectra and shear modulus depend on the Sr
Wu Xiu Sheng   +3 more
doaj   +1 more source

Laser scanning reflection-matrix microscopy for aberration-free imaging through intact mouse skull

open access: yesNature Communications, 2020
Microscopic imaging of the brain usually requires thinning of the skull, as it causes complex aberration. Here, the authors introduce a label-free imaging modality termed laser scanning reflection-matrix microscopy, which allows for correcting these ...
Seokchan Yoon   +4 more
doaj   +1 more source

Thermal accommodation in nanoporous silica for vacuum insulation panels

open access: yesInternational Journal of Thermofluids, 2020
The thermal accommodation coefficient is a measure for the quality of thermal energy exchange between gas molecules and a solid surface. It is an important parameter to describe heat flow in rarefied gases, for example, in aerospace or vacuum technology.
S. Sonnick   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Rebuttal to "Comment by V.M. Krasnov on 'Counterintuitive consequence of heating in strongly-driven intrinsic junctions of Bi2Sr2CaCu2O8+d Mesas' " [PDF]

open access: yes, 2010
In our article [1], we found that with increasing dissipation there is a clear, systematic shift and sharpening of the conductance peak along with the disappearance of the higher-bias dip/hump features (DHF), for a stack of intrinsic Josephson junctions (
Gray, Kenneth E.   +6 more
core   +3 more sources

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

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