Results 61 to 70 of about 5,284,833 (331)
Professor Robert Schaller: Zener Medalist
The following is the text of an oral presentation delivered at the Zener Medal Award ceremony in Hefei on 23 September 2015.
Mari D.
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
In this work, we present mechanical spectroscopy of cold work tool steel subjected to sub-zero cryogenic soaking treatment to reveal the carbon segregation and the subsequent carbides refinement.
Min N., Li H.M., Xie CH., Wu X.C.
doaj +1 more source
Hidden area and mechanical nonlinearities in freestanding graphene [PDF]
We investigated the effect of out-of-plane crumpling on the mechanical response of graphene membranes. In our experiments, stress was applied to graphene membranes using pressurized gas while the strain state was monitored through two complementary ...
Bolotin, Kirill I. +4 more
core +2 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The industrial particle sensor market lacks simple, easy to use, low cost yet robust, safe and fast response solutions. Towards development of such a sensor, for in-line use in micro channels under continuous flow conditions, this work introduces static ...
Jesse Ross-Jones +7 more
doaj +1 more source
Preparation, physical-chemical characterisation and cytocompatibility of calcium carbonate cements [PDF]
The feasibility of calcium carbonate cements involving the recrystallisation of metastable calcium carbonate varieties has been demonstrated. Calcium carbonate cement compositions presented in this paper can be prepared straightforwardly by simply mixing
Aizenberg +67 more
core +2 more sources
Low Frequency Mechanical Spectroscopy Study of Three Pyrrolidinium Based Ionic Liquids
In this work we present our recent results on three ionic liquids (ILs), which share bis(trifluoromethanesulfonyl)imide (TFSI) as anion and have different pyrrolidinium based cations.
F. Trequattrini +5 more
semanticscholar +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source

