Results 41 to 50 of about 1,892,709 (308)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

In Situ Nanomechanical Measurements of Interfacial Strength in Membrane-Embedded Chemically Functionalized Si Microwires for Flexible Solar Cells [PDF]

, 2012
Arrays of vertically aligned Si microwires embedded in polydimethylsiloxane (PDMS) have emerged as a promising candidate for use in solar energy conversion devices.
Cho, Clara J., Greer, Julia R., Lewis, Nathan S., O’Leary, Leslie   +3 more
core   +2 more sources

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason, John P. Woodhouse, Joanna S. Yi, M. Monica Gramatges, Olga A. Taylor, Veronica A. Morales, Shalini Dhamodharan, Marley Roberts, Karen R. Rabin, Philip J. Lupo, Michael E. Scheurer, Van Huynh, Steven D. Mittelman, Etan Orgel, Austin L. Brown   +14 more
wiley   +1 more source

Aeroelastic Stability Analysis of a Laminated Composite Sandwich Panel With a Magnetorheological Fluid Core Under Yawed Supersonic Airflow

International Journal of Aerospace Engineering
In this study, we conducted an aeroelastic stability analysis of a laminated composite magnetorheological fluid (MRF) sandwich panel in supersonic airflow for varying yawed angles.
Jian Zhou, Liang Li, Minglong Xu
doaj   +1 more source

Cooling mechanical resonators to quantum ground state from room temperature

, 2014
Ground-state cooling of mesoscopic mechanical resonators is a fundamental requirement for test of quantum theory and for implementation of quantum information. We analyze the cavity optomechanical cooling limits in the intermediate coupling regime, where
Dong, Chun-Hua, Gong, Qihuang, Li, Yan, Liu, Rui-Shan, Liu, Yong-Chun, Xiao, Yun-Feng   +5 more
core   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Dynamic model of ion and water transport in ionic polymer-metal composites

AIP Advances, 2011
In the process of electro-mechanical transduction of ionic polymer-metal composites (IPMCs), the transport of ion and water molecule plays an important role.
Zicai Zhu, Hualing Chen, Longfei Chang, Bo Li   +3 more
doaj   +1 more source

Determination of wood strength properties through standard test procedures [PDF]

, 2012
In this study a review of existing recognised standards for wood mechanical testing was conducted. This review considers tensile, compressive, bending and shear test methodologies from a range of sources.
Hackney, Philip, Naylor, Andrew, Perera, Noel   +2 more
core  

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Numerical Research of an Ice Accretion Delay Method by the Bio-Inspired Leading Edge

Aerospace, 2022
The accumulation of ice on aircraft is a typical meteorological issue. The ice accretion on the wing’s leading edge can cause an earlier stall and significantly increase the safety risks.
Xiaogang Xu, Tianbo Wang, Yifan Fu, Yang Zhang, Gang Chen   +4 more
doaj   +1 more source