Results 61 to 70 of about 1,892,709 (308)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Polyamide 11-Carbon Nanotubes Nanocomposites: Preliminary Investigation [PDF]

open access: yes, 2008
The objective of this research is to develop an improved polyamide 11 (PA11) polymer with enhanced flame retardancy, thermal, and mechanical properties for selective laser sintering (SLS) rapid manufacturing.
Koo, J. H.   +9 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Sieving Performance of Dual-Track Shale Shaker Based on DEM-MBD Coupling

open access: yesShiyou jixie
To improve the processing capacity of the shale shaker, meet the needs of different working conditions in the drilling process, and solve the problems of “screen blinding” and “mud runaway” occurring in the existing shale shaker, a “linear + variable ...
Lü Zhipeng   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Vision-Based Damage Detection Method Using Multi-Scale Local Information Entropy and Data Fusion

open access: yesApplied Sciences
Low-spatial-resolution measurements from contact sensors and excessive measurement noise have impeded the implementation of vibration-based damage detection.
Yiming Zhang, Zili Xu, Guang Li, Cun Xin
doaj   +1 more source

Ultra-broadband acoustic absorption with inhomogeneous high-order Fabry–Pérot resonances

open access: yesAPL Materials, 2023
We present an ultra-broadband acoustic metamaterial with inhomogeneous high-order Fabry–Pérot (FP) resonances that achieves near-perfect continuous absorption in the range of 400–10000 Hz.
Chongrui Liu   +4 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Mechanical Properties of the Mineral Cast Material at the Macro and Micro Level. [PDF]

open access: yes, 2016
The paper presents the results of experimental examination of the mechanical properties at micro and macro scale of the mineral cast composites. Studies have been conducted to verify the literature data about the value of tensile strength, compressive ...
Kaczmarek, Łukasz   +3 more
core  

Single cell mechanics: stress stiffening and kinematic hardening

open access: yes, 2007
Cell mechanical properties are fundamental to the organism but remain poorly understood. We report a comprehensive phenomenological framework for the nonlinear rheology of single fibroblast cells: a superposition of elastic stiffening and viscoplastic ...
A. Mogilner   +10 more
core   +1 more source

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