Results 81 to 90 of about 4,274,589 (298)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Optimizing the Density of Holes of EWT Solar Cells Taking Into Consideration Mechanical Aspects [PDF]

open access: yes, 2011
EWT solar cells start from drilled wafers with approximately 100 holes/cm2. These holes act as stress concentrators leading to a reduction in the mechanical strength of this type of wafers.
Alarcón Álvarez, Enrique   +4 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Oxygen-terminated M4X3 MXenes with superior mechanical strength

open access: yes, 2021
Two-dimensional (2D) transition metal carbides and nitrides, known as MXenes, have gained notable attention recently because these super-strong materials have many promising applications.
Wang, Y   +3 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Origin and tuning of bandgap in chiral phononic crystals

open access: yesCommunications Physics
The wave equation revealing the wave propagation in chiral phononic crystals, established through force equilibrium law, conceals the underlying physical information, such as the essence of the motion coupling and the inertial amplification effect.
Wei Ding   +8 more
doaj   +1 more source

Mechanism of Mechanical Strengths for Corrugated Fiberboard.

open access: yesJAPAN TAPPI JOURNAL, 1994
Mechanism of mechanical strengths is discussed for corrugated fiberboards of single face, single wall and double wall. The strength under the tensile load is discussed by the experimental results of the tensile deformation. Their strengths under the surface compression and the uniform bending made from the applied moment of the axis along the machine ...
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Experimental Investigation and Safety Classification Evaluation of Small Drone Collision with Humans

open access: yesBiomimetics
The safety of small drones in collision with humans has become a key focus in engineering and research fields. This study presents a vertical drop test platform for collision tests involving three representative drones (Air, Mavic 2, and M200) impacting ...
Chunyu Bai   +5 more
doaj   +1 more source

Determination of the Strain-Free Configuration of Multispan Cable

open access: yesShock and Vibration, 2015
For building a reasonable finite element geometric model, a method is proposed to determine the strain-free configuration of the multispan cable. The geometric conditions (the end conditions and the unstretched length conditions) as constraints for the ...
Chuancai Zhang, Qiang Guo, Xinhua Zhang
doaj   +1 more source

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