Results 101 to 110 of about 7,604,628 (414)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Relação entre rigidez de fixador externo e quantidade de pinos: análise computacional por elementos finitos Relationship between rigidity of external fixator and number of pins: computer analysis using finite elements

open access: yesRevista Brasileira de Ortopedia, 2012
OBJETIVO: Analisar a rigidez da montagem de um fixador externo tipo plataforma, segundo diferentes números de pinos em cada clamp. MÉTODOS: Realizou-se simulação computacional do fixador externo dinâmico modelo Cromus tamanho grande (Baumer S.A.) por ...
Marcelo Back Sternick   +3 more
doaj   +1 more source

Mechanotransduction in fibroblasts [PDF]

open access: yes, 2011
Response to mechanical stress is important for tissue homeostasis, tissue architecture and muscle regeneration. All cells of an organism are subject to at least one of three types of mechanical stress: compression, shear stress or tension.
Brosig, Michaela
core   +1 more source

Neural Mechanisms of Stress Resilience and Vulnerability [PDF]

open access: yesNeuron, 2012
Exposure to stressful events can be differently perceived by individuals and can have persistent sequelae depending on the level of stress resilience or vulnerability of each person. The neural processes that underlie such clinically and socially important differences reside in the anatomical, functional, and molecular connectivity of the brain. Recent
Franklin Tamara B   +2 more
openaire   +4 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Electromechanical Analysis of the Medium Voltage Earthing Switch due to Short-Time and Peak Withstand Current Test

open access: yesEnergies, 2019
The chosen electrical equipment, i.e., the earthing switch has its application in marine switchgear. In this paper, the reduction of dimensions is considered with the purpose of making it more energy efficient in terms of onboard application.
Maja Krčum   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Stress Monitoring of Civil and Mechanical Engineering Infrastructure

open access: yes, 2007
Structural Integrity Monitoring is a rapidly growing science and practice which promises in the future to measure and record every shudder and twitch within the lifetime of future structural components.
Brennan, Feargal P.
core  

Numerical stress analysis in adhesively bonded joints under thermo-mechanical loading

open access: yes, 2020
The objective of this work is to evaluate the effect of residual thermal stresses, arising after assembling a single-lap joint at elevated temperature, on the inelastic thermo-mechanical stress state in the adhesive layer.
Joffe, Roberts,   +2 more
core   +1 more source

Mechanical properties of mesoporous ceria nanoarchitectures [PDF]

open access: yes, 2014
Architectural constructs are engineered to impart desirable mechanical properties facilitating bridges spanning a thousand meters and buildings nearly 1 km in height.
Sayle, T.X.T.   +10 more
core   +1 more source

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