Results 171 to 180 of about 7,604,628 (414)

Reply: The stresses of cardiovascular mechanics [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2020
Keshava, Rajagopal   +2 more
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Mechanical Stress Induced NOX2 Promotes Endothelial Dysfunction in Ventilator‐Induced Lung Injury: Potential Treatment with Quercetin

open access: yesAdvanced Science
Mechanical ventilation (MV) is a treatment that helps people who are unable to breathe on their own. However, the use of MV leads to the development of ventilator‐induced lung injury (VILI). Here, it is found that VILI with endothelial barrier disruption
Tao Jiang   +8 more
doaj   +1 more source

Mechanical Properties of Coronary Veins

open access: yes, 2008
There are several publications available and experiments were done regarding to the vessel biomechanical properties. In the range we could find in vitro and in vivo assessments data for elasticity properties.
Dobránszky, János   +3 more
core  

Synchrotron strain scanning for residual stress measurement in cold-drawn steel rods

open access: yes, 2011
Cold-drawn steel rods and wires retain significant residual stresses as a consequence of the manufacturing process. These residual stresses are known to be detrimental for the mechanical properties of the wires and their durability in aggressive ...
M Elices   +5 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Force-Loaded Cementocytes Regulate Osteoclastogenesis Via S1p/S1pr1/ Rac1 Axis

open access: yesInternational Dental Journal
Aim or purpose: This study elucidates the pivotal role of the sphingosine-1-phosphate (S1P)/S1PR1/Rac1 axis in cementocyte-regulated osteoclastogenesis during orthodontically induced inflammatory root resorption (OIIRR).
Han Wang
doaj   +1 more source

Modelling and predicting fatigue crack growth behaviour in weld induced residual stress fields [PDF]

open access: yes, 2011
In the last few decades, new design concepts and manufacture processes have been developed in order to reduce the maintenance and manufacturing costs, and structural weight of aircraft components. The integral metallic structure with welding processes
Servetti, Guido
core  

Molecular Mechanism of Mechanical Stress-Induced Cardiac Hypertrophy

open access: yesJapanese Heart Journal, 2000
Mechanical stress is a major cause of cardiac hypertrophy. Although the mechanisms by which mechanical load induces cardiomyocyte hypertrophy have long been a subject of great interest for cardiologists, the lack of a good in vitro system has hampered the understanding of the biochemical mechanisms.
openaire   +3 more sources

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