Results 191 to 200 of about 7,604,628 (414)

Mechanical evaluation of EGUH burs in dentin during guided endodontics: Finite element analysis

open access: yesSaudi Endodontic Journal
Introduction: This study investigated the mechanical and thermal behavior of EGUH burs used in guided endodontics through simulations performed using Finite Element Analysis.
Luis Geovanny Suárez Guerrero   +3 more
doaj   +1 more source

Mechanical properties of tree roots for soil reinforcement models

open access: yes, 2001
Evidence from forestry has shown that part of the forest floor bearing capacity is delivered by tree roots. The beneficial effect however varies and diminishes with increasing number of vehicle passes. Roots potential for reinforcing the soil is known to
Cofie, P.
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

FGF9–FGFR2 Signaling via Osteocytes‐Preosteoblasts Crosstalks to Mediate Mechanotransduction‐Driven Intramembranous Osteogenesis in the Underdeveloped Maxilla

open access: yesAdvanced Science
Maxillary underdevelopment is a critical component of skeletal Class III malocclusion, closely linked to altered biomechanical signaling. Mechanical stimulation through early facemask protraction can effectively promote maxillary growth, yet the ...
Yiwen Zhou   +15 more
doaj   +1 more source

Epithelial–mesenchymal transition in pulmonary fibrosis: molecular mechanisms and emerging therapeutic strategies

open access: yesFrontiers in Medicine
Pulmonary fibrosis is a progressive lung-scarring disease for which curative options remain limited. This review examines how epithelial–mesenchymal transition (EMT) contributes to fibrotic remodeling in subsets of pulmonary fibrosis (PF), delineates ...
Weiyi Li   +11 more
doaj   +1 more source

Involvement of mechanical stress in androgenetic alopecia

open access: yesInternational Journal of Trichology, 2015
Androgenetic alopecia (AGA) is a frequent disorder characterized by progressive hair miniaturization in a very similar pattern among all affected men. The pathogenesis is related to androgen-inducible overexpression of transforming growth factor β-1 from balding dermal papilla cells, which is involved in epithelial inhibition and perifollicular ...
openaire   +3 more sources

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

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