Results 201 to 210 of about 7,604,628 (414)
Supramolecular assembly and mechanical properties of dermis
, 2007 The present work is a part of a wider research project which aims at the in vitro tissues and biohybrid generation. The process of generating biological tissues requires benchmarks in order to define the optimal set of design and performance parameters ...
Ventre, Maurizio
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Thermo-Mechanical Simulation Model Development on Residual Stresses in Rolled Aluminium Alloy
, 2018 Purnendu Mondal, C. Pinna
openalex +1 more source
Mechanical Behaviour of Materials: Stress analysis and Mohr's circle
, 2010 This set of animations explains how to use the Mohr's circle in stress analysis.
DoITPoMS, University of Cambridge +3 more
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The Effect of Duration of Stress Relief Heat Treatments on Microstructural Evolution and Mechanical Properties in Grade 91 and 92 Power Plant Steels [PDF]
, 2010 L. Li +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Stress-dilatancy Relation for Mohr-Coulomb Soils Following a Non-Associated Flow Rule
, 2010 Rowe\u27s stress–dilatancy relation for frictional (cohesionless) materials has been a cornerstone of soil mechanics. The original derivation of this relationship was based on incorrect energy minimisation considerations, but the relationship was proven ...
Salgado, Rodrigo, Zhang, J
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