Results 131 to 140 of about 478,260 (264)

Automated and manual model creation workflows are equally reliable for virtual mechanical testing of ovine bone and fracture healing. [PDF]

Sci Rep
Bahrami M, Ariyanfar A, Klein K, von Rechenberg B, Darwiche S, Dailey HL.   +5 more
europepmc   +1 more source

Microscale and Macroscale Deformation Behavior of Electrospun Polymeric Nanofiber Membranes Using In Situ SEM during Mechanical Testing. [PDF]

Polymers (Basel), 2023
Verschatse O, Loccufier E, Swanckaert B, De Clerck K, Daelemans L.   +4 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Experimental datasets from mechanical testing and characterization of composites filled with PVCs waste. [PDF]

Data Brief
Nugraha AD, Purnomo E, Afandi FR, Wijayanto H, Yudha NK, Supriyanto E, Nugroho AD, Muflikhun MA.   +7 more
europepmc   +1 more source

A Bayesian constitutive model selection framework for biaxial mechanical testing of planar soft tissues: Application to porcine aortic valves. [PDF]

J Mech Behav Biomed Mater, 2023
Aggarwal A, Hudson LT, Laurence DW, Lee CH, Pant S.   +4 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Density-Based Topology-Optimized 3D-Printed Fixtures for Cyclic Mechanical Testing of Lattice Structures. [PDF]

Polymers (Basel)
Castro J, Valle R, Leiva J, Oñate A, Saggionetto E, Mertens A, Tuninetti V.   +6 more
europepmc   +1 more source

Vibrometry as a noncontact alternative to dynamic and viscoelastic mechanical testing in cartilage. [PDF]

J R Soc Interface, 2021
Espinosa MG, Otarola GA, Hu JC, Athanasiou KA.   +3 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A Comprehensive Mechanical Testing of Polyacrylamide Hydrogels: The Impact of Crosslink Density. [PDF]

Polymers (Basel)
Antipova CG, Krupnin AE, Zakirov AR, Pobezhimov VV, Romanenko DA, Stolyarova DY, Chvalun SN, Grigoriev TE.   +7 more
europepmc   +1 more source