Results 151 to 160 of about 5,211,707 (295)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Journal of the American Society of Mechanical Engineers.

Mode of access ...
American Society of Mechanical Engineers.
core  

Comparison of lithium disilicate and feldspathic CAD-on systems in implant-supported crowns: a combined mechanical testing and FEA study. [PDF]

Int J Implant Dent
Yeğin E, Atala MH.
europepmc   +1 more source

Advanced Mechanical Testing Technologies at the Cellular Level: The Mechanisms and Application in Tissue Engineering. [PDF]

Polymers (Basel), 2023
Zhu Y, Zhang M, Sun Q, Wang X, Li X, Li Q.   +5 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

EVALUATION OF SPECIMEN GEOMETRY FOR RELIABLE MECHANICAL TESTING OF THERMOPLASTIC ALIGNER MATERIALS

A thorough understanding of the variuos mechanical properties of thermoplastic materials is crucial for effective aligner treatment. The appropriate testing parameters and specimen shape for mechanical testing of aligners must be determined in order to ...
Marković, Jelena, Milovanović, Aleksa, Mitrović, Nenad, Mitrović, Aleksandra, Travica, Milan, Pajević, Tina   +5 more
core  

Pre-Impregnated Powder Coatings with a Thermoplastic Matrix for Use in Fibre-Reinforced Polymer Sandwich Composites: Manufacturing, Mechanical Testing and Finite Element Modelling. [PDF]

Materials (Basel)
Golewski P, Budka M.
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Integration of Mechanical Testing, In Vivo Optical Coherence Elastography and Personalized Finite Element Modeling to Predict Geometrical Outcomes of Corneal Cross-Linking. [PDF]

Ann Biomed Eng
Frigelli M, Lohmüller R, Gracia MAA, Schlunck G, Lang SJ, Torres-Netto EA, Hafezi F, Büchler P, Kling S.   +8 more
europepmc   +1 more source

A Miniaturized Device Coupled with Digital Image Correlation for Mechanical Testing. [PDF]

Micromachines (Basel), 2022
Cruz DJ, Xavier J, Amaral RL, Santos AD.
europepmc   +1 more source