Results 171 to 180 of about 1,715,737 (308)

Geometric Parameter Optimization of 3D-Printed Microneedle Arrays Based on Comprehensive Mechanical Testing and Failure Analysis. [PDF]

Micromachines (Basel)
Aldawood FK, Abualkhair HF.
europepmc   +1 more source

Fabrication and Mechanical Testing of the Uniaxial Graded Auxetic Damper. [PDF]

Materials (Basel), 2022
Al-Rifaie H, Novak N, Vesenjak M, Ren Z, Sumelka W.   +4 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Automated and manual model creation workflows are equally reliable for virtual mechanical testing of ovine bone and fracture healing. [PDF]

Sci Rep
Bahrami M, Ariyanfar A, Klein K, von Rechenberg B, Darwiche S, Dailey HL.   +5 more
europepmc   +1 more source

Microscale and Macroscale Deformation Behavior of Electrospun Polymeric Nanofiber Membranes Using In Situ SEM during Mechanical Testing. [PDF]

Polymers (Basel), 2023
Verschatse O, Loccufier E, Swanckaert B, De Clerck K, Daelemans L.   +4 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Experimental datasets from mechanical testing and characterization of composites filled with PVCs waste. [PDF]

Data Brief
Nugraha AD, Purnomo E, Afandi FR, Wijayanto H, Yudha NK, Supriyanto E, Nugroho AD, Muflikhun MA.   +7 more
europepmc   +1 more source

A Bayesian constitutive model selection framework for biaxial mechanical testing of planar soft tissues: Application to porcine aortic valves. [PDF]

J Mech Behav Biomed Mater, 2023
Aggarwal A, Hudson LT, Laurence DW, Lee CH, Pant S.   +4 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Density-Based Topology-Optimized 3D-Printed Fixtures for Cyclic Mechanical Testing of Lattice Structures. [PDF]

Polymers (Basel)
Castro J, Valle R, Leiva J, Oñate A, Saggionetto E, Mertens A, Tuninetti V.   +6 more
europepmc   +1 more source