Results 181 to 190 of about 1,715,737 (308)

Vibrometry as a noncontact alternative to dynamic and viscoelastic mechanical testing in cartilage. [PDF]

J R Soc Interface, 2021
Espinosa MG, Otarola GA, Hu JC, Athanasiou KA.   +3 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

A Comprehensive Mechanical Testing of Polyacrylamide Hydrogels: The Impact of Crosslink Density. [PDF]

Polymers (Basel)
Antipova CG, Krupnin AE, Zakirov AR, Pobezhimov VV, Romanenko DA, Stolyarova DY, Chvalun SN, Grigoriev TE.   +7 more
europepmc   +1 more source

Mechanical testing of transtibial prosthetic sockets: A discussion paper from the American Orthotic and Prosthetic Association Socket Guidance Workgroup. [PDF]

Prosthet Orthot Int, 2023
Gariboldi F, Cutti AG, Fatone S, Nickel E, Dickinson A, Steer J, Erenstone J, Zahedi S, AOPA Socket Guidance Workgroup.   +8 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Multimodal Evaluation of Three NiTi Rotary Systems: Clinical Simulation, Mechanical Testing, and Finite Element Analysis. [PDF]

Dent J (Basel)
Aparicio JA, Mendez S PM, Malvicini G, Grandini S, Gaeta C, García Guerrero AP, Miranda Robles KL, Aranguren J, Pérez AR.   +8 more
europepmc   +1 more source

Comparative mechanical testing for different orthodontic aligner materials over time - in vitro study. [PDF]

J Clin Exp Dent, 2022
Nowak CM, Othman A, Ströbele DA, von See C.   +3 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Surface and Subsurface Mechanical Testing at the Nanoscale: A Review on Ultrasonic Atomic Force Microscopy. [PDF]

Langmuir
Ma C, Zhou F.
europepmc   +1 more source

Fabricating a Low-Cost, Microscopy-Compatible Mechanical Testing Device. [PDF]

Exp Tech, 2022
Mehta SM, De Santos DR, Sridhar S, Aguayo VC, Meraz CA, Mikos M, Grande-Allen KJ.   +6 more
europepmc   +1 more source