Results 141 to 150 of about 1,715,737 (308)

Brazed Borsic/aluminum structural panels [PDF]

A fluxless brazing process has been developed that minimizes degradation of the mechanical properties of Borsic/aluminum composites. The process, which employs 718 aluminum alloy braze, is being used to fabricate full scale Borsic/aluminum-titanium ...
Bales, T. T., Royster, D. M., Wiant, H. R.   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Ranking Technologies of Additive Manufacturing of Removable Complete Dentures by the Results of Their Mechanical Testing. [PDF]

Dent J (Basel), 2023
Grachev DI, Zolotnitsky IV, Stepanov DY, Kozulin AA, Mustafaev MS, Deshev AV, Arutyunov DS, Tlupov IV, Panin SV, Arutyunov SD.   +9 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Experimental and Numerical Study of a Turbulent Multiple Jets Issued from Lobed Diffusers

Journal of Applied Fluid Mechanics, 2019
A combined experimental and computational study of a turbulent multiple jet from lobed diffusers is performed. The main interest of these multiple lobed jets is to come up with the best configuration that improves the thermal and dynamic homogenization ...
W. Medaouar, L. Loukarfi, M. Braikia, A. Khelil, H. Naji   +4 more
doaj  

Mechanical testing and comparison of porcine tissue, silicones and 3D-printed materials for cardiovascular phantoms. [PDF]

Front Bioeng Biotechnol, 2023
Illi J, Ilic M, Stark AW, Amstutz C, Burger J, Zysset P, Haeberlin A, Gräni C.   +7 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Improved techniques for thermomechanical testing in support of deformation modeling [PDF]

The feasibility of generating precise thermomechanical deformation data to support constitutive model development was investigated. Here, the requirement is for experimental data that is free from anomalies caused by less than ideal equipment and ...
Castelli, Michael G., Ellis, John R.
core   +1 more source

Hair-Reinforced Elastomer Matrix Composites: Formulation, Mechanical Testing, and Advanced Microstructural Characterization. [PDF]

Polymers (Basel), 2023
Statnik ES, Cvjetinovic J, Ignatyev SD, Wassouf L, Salimon AI, Korsunsky AM.   +5 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source