Results 141 to 150 of about 478,260 (264)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Multimodal Evaluation of Three NiTi Rotary Systems: Clinical Simulation, Mechanical Testing, and Finite Element Analysis. [PDF]

open access: yesDent J (Basel)
Aparicio JA   +8 more
europepmc   +1 more source

Fabricating a Low-Cost, Microscopy-Compatible Mechanical Testing Device. [PDF]

open access: yesExp Tech, 2022
Mehta SM   +6 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Mechanical testing of transtibial prosthetic sockets: A discussion paper from the American Orthotic and Prosthetic Association Socket Guidance Workgroup. [PDF]

open access: yesProsthet Orthot Int, 2023
Gariboldi F   +8 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Mitigation of image distortion during mechanical testing within a dynamic stereo x-ray system. [PDF]

open access: yesFront Bioeng Biotechnol
Paglia DN   +9 more
europepmc   +1 more source

Robot and mechanical testing of a specialist manual toothbrush for cleaning efficacy and improved force control. [PDF]

open access: yesBMC Oral Health, 2022
Acherkouk A   +6 more
europepmc   +1 more source

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