Results 101 to 110 of about 2,381 (165)

The correlation of whole blood viscosity and outcome in mechanical thrombectomy for acute ischemic stroke

Frontiers in Stroke
IntroductionWhole blood viscosity (WBV), reflecting the intrinsic resistance of blood flow, is an established predictor of stroke events in individuals.
Monika Thapa, Jordyn Courville, Reese Leonhard, Prabandh Buchhanolla, Mohammad Abdurrehman Sheikh, Rahul Shah, Prashant Rai, Himanshu Chokhawala, Md Ismail Hossain, Mohammad Alfrad Nobel Bhuiyan, J. Dedrick Jordan, Roger E. Kelley   +11 more
doaj   +1 more source

Surgical Treatment of Lung Adenocarcinoma Tumor Thrombus Extending Into the Left Atrium: A Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT When lung adenocarcinoma is accompanied by a tumor thrombus that extends through the pulmonary veins to the left atrium, it is an extremely rare case, and the disease is already at stage IIIA. The available treatment methods are also quite limited.
Zhongjian Chong, Yu Tang, Aiping Zhang, Zijian Ma   +3 more
wiley   +1 more source

Endovascular Mechanical Thrombectomy for Ischemic Stroke Treatment in the Setting of Aortic Dissection: Case Report

Case Reports in Neurology
Introduction: Acute ischemic stroke can occur in the setting of aortic dissection. Information concerning the utility of endovascular mechanical thrombectomy as an intervention for patients with aortic dissection who are experiencing an acute stroke due ...
Luis Alberto Cruz-Saavedra, Jeet Patel, Daniel Siragusa, Scott L. Silliman   +3 more
doaj   +1 more source

Restricting Synaptotagmin‐3 Internalization Mitigates Cerebral Ischemia/Reperfusion Injury by Curtailed Neuronal Apoptosis and Microglial Re‐Programming

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
Restriction of Syt3 internalization by peptide 3Y conferred robust neuroprotection against cerebral ischemia/reperfusion injury. Mechanistically, 3Y suppressed neuronal apoptosis fundamentally, and additionally, these salvaged neurons orchestrated and remodulated the transformation of surrounding microglia toward an anti‐inflammatory and ...
Hua Xu, Hongbo Mi, Rong Cheng, Tiantian Gui, Fangzhou Hu, Yi Yang, Jian Cheng, Qun Xue   +7 more
wiley   +1 more source

Relationship Between Baseline Infarct and Clinical Outcome in Pediatric Large‐Vessel Occlusion Ischemic Stroke

Stroke: Vascular and Interventional Neurology
Background In adults with large‐vessel occlusion stroke, the extent of the baseline infarct measured using the Alberta Stroke Program Early Computed Tomography Score (ASPECTS) predicts outcome and is used during patient selection for mechanical ...
Kartik D. Bhatia, Carmen Parra‐Farinas, Elizabeth Pulcine, Nomazulu Dlamini, Ian Andrews, Sachin Gupta, Richard Webster, Christopher Troedson, Russell C. Dale, John Worthington, Kylie Tastula, Timothy Ang, Andrew Cheung, Nathan Manning, Ferdinand Miteff, Christina Miteff, Prakash Muthusami   +16 more
doaj   +1 more source

IL‐17A Promotes NETs Formation via the PKCζ–ERK–ROS–PAD4 Pathway in a Mouse Model of Ischemic Stroke

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
Our study demonstrates that IL‐17A promotes NET formation by upregulating PAD4 through the PKCζ–ERK–ROS pathway, thereby exacerbating ischemic brain injury. IL‐17A regulates NET formation through this newly identified molecular pathway, and targeting this pathway may offer a novel therapeutic strategy for stroke.
Chang Liu, Qi Chen, Weijia Chen, Xinyue Han, Xiaowen Qiao, Jun Guo, Wei Su, Qingqing Dai   +7 more
wiley   +1 more source

Pan‐Immune‐Inflammation Value for Mortality Risk Stratification in Critically Ill Patients With Acute Ischemic Stroke: A Cohort Study Based on the MIMIC‐IV Database

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
This study identified a nonlinear, reverse L‐shaped relationship between the pan‐immune‐inflammation value (PIV) and all‐cause mortality (ACM) in critically ill acute ischemic stroke (AIS) patients, with a distinct threshold for risk stratification. Furthermore, the prognostic value of PIV was significantly stronger in patients without sepsis.
Zhenzhu Li
wiley   +1 more source

Traditional Chinese Herbal Formula XuMingZhuSan Alleviates Neuronal Ferroptosis in Rats After Stroke by Activating the NRF2/GPX4/SLC7A11 Pathway

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
Traditional Chinese herbal formula XuMingZhuSan showed its efficacy in treating stroke. It was capable of attenuating neuronal damage and mitochondrial damage and reducing infarction volume in rats with stroke. Mechanically, XuMingZhuSan might treat stroke by relieving neuronal ferroptosis via activating the NRF2/GPX4/SLC7A11 pathway.
Xi Liu, Cheng Wang, Ling Han, Yian Xiao, Hanchang Yu, Zhongxu Hu, Xiyun Fei, Min Peng, Jilin Zhou, Zhijun Zhong   +9 more
wiley   +1 more source

Successful Emergency Cardiac Surgery for Intraoperative Pulmonary Artery Tumor Embolism During Renal Cell Carcinoma Surgery: A Case Report

IJU Case Reports, Volume 9, Issue 2, March 2026.
ABSTRACT Introduction Intraoperative tumor thrombus embolization during renal cell carcinoma (RCC) surgery with inferior vena cava (IVC) tumor thrombus is a rare but potentially fatal complication. We report successful emergency cardiac surgery for massive pulmonary artery tumor embolism.
Toshiki Kijima, Akihiko Nagoshi, Kento Kobayashi, Ryo Nagaoka, Yuya Sato, Takashi Kato, Shinsuke Hamagchi, Shigeki Yamaguchi, Hirotsugu Fukuda, Takao Kamai   +9 more
wiley   +1 more source

The Role of Extracellular Vesicles in Transient Ischaemic Attacks and Ischaemic Stroke: A Systematic Review

Journal of Extracellular Biology, Volume 5, Issue 3, March 2026.
Both transient ischaemic attack (TIA) and ischaemic stroke lead to an increase in individual cellular‐derived populations of extracellular vesicles (EVs), including endothelial, platelet and leukocyte derived. These EVs have downstream roles in the pathophysiological events associated with TIA and stroke, including dysregulated inflammation and ...
Rebecca Marie Raven, Philip Eurig James, Keith Morris, Jessica Olivia Williams   +3 more
wiley   +1 more source