Results 101 to 110 of about 2,564,199 (338)

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Direct mechanical thrombectomy without intravenous thrombolysis versus bridging therapy for acute ischemic stroke: A meta-analysis of randomized controlled trials

International Journal of Stroke, 2021
Background Direct mechanical thrombectomy may result in similar outcomes compared to a bridging approach with intravenous thrombolysis (IVT + MT) in acute ischemic stroke. Recent randomized controlled trials have varied in their design and noninferiority
A. Podlasek, P. Dhillon, Waleed Z. Butt, I. Grunwald, T. England   +4 more
semanticscholar   +1 more source

Magnetically‐Induced Suppression of Oxidative Stress Prevents Venous Thrombosis

Advanced Science, EarlyView.
Venous thromboembolism (VTE) remains a leading cause of cardiovascular mortality. This study demonstrates that static magnetic fields (SMF) offer a novel non‐pharmacological intervention against VTE by mitigating endothelial oxidative stress. Mechanistically, SMF elevates intracellular Ca2+, boosts ATP production, and suppresses NOX4‐mediated ROS ...
Nana Zhang, Yirong An, Shiran Tao, Shenao Qu, Minge Wu, Guantong Fang, Ziqing Chen, Weilun Song, Haoze Leng, Rongqian Wu, Yi Lyu, Xiaoli Liu, Dinghui Dong   +12 more
wiley   +1 more source

Radiation outcome in mechanical thrombectomy of acute ischemic stroke

Translational Neuroscience, 2019
Mechanical thrombectomy is recommended for acute ischemic stroke (AIS) with large artery occlusion. Radiation during the endovascular procedure would increase the risk of skin diseases.
Cai Xiaoying, Ding Xianhui, Wang Wenbin, Yang Ke, Zhou Zhiming, Fang Yannan, Shi XiaoLei   +6 more
doaj   +1 more source

Comparative study on treatment of acute cerebral infarction between mechanical thrombectomy by micro catheter and thrombectomy by Solitaire AB stent

Medicine, 2022
. Background:. Acute cerebral artery occlusion is a common disease with high morbidity and mortality. At present, the commonly used mechanical thrombectomy schemes are mechanical thrombectomy and stent thrombectomy.
Xiaoli Dong, MM, Guodong Xu, MD, Yaxue Song, MM, Liang Ma, MM, Tiantian Huo, MM, Nan Yin, MD, Nan Meng, MM, Ahmed Salah Naser.   +7 more
doaj   +1 more source

Jefferson Digital Commons quarterly report: January-March 2020 [PDF]

, 2020
This quarterly report includes: New Look for the Jefferson Digital Commons Articles COVID-19 Working Papers Educational Materials From the Archives Grand Rounds and Lectures JeffMD Scholarly Inquiry Abstracts Journals and Newsletters Master of Public ...
Copeland, LIBT, James, Duinkerken, MSI, Kelsey, Gordon, MSLIS, MEd, MA, Larissa   +2 more
core   +1 more source

The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection—evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology [PDF]

, 2018
Due to its poor capacity for regeneration, the heart is particularly sensitive to the loss of contractile cardiomyocytes. The onslaught of damage caused by ischaemia and reperfusion, occurring during an acute myocardial infarction and the subsequent ...
A Ames 3rd, A Carvalho, A Gaspar, A Maulik, AA Neuhaus, AC Schinzel, AD Sloth, Arjun K. Ghosh, AS Hazell, B Ibanez, B Ibanez, Borja Ibanez, CC Smith, CE Murry, CP Baines, D Li, Daniel I. Bromage, Derek M. Yellon, DI Bromage, DJ Hausenloy, DJ Hausenloy, DJ Hausenloy, DJ Hausenloy, DJ Hausenloy, ET Chouchani, F Chauveau, F Chen, F Pedersen, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, GA Donnan, GA Donnan, Gerd Heusch, GF Baxter, GP Fadini, GW Stone, H Sandhu, HA Cabrera-Fuentes, Hans Erik Bøtker, HE Botker, Helen Maddock, I Eitel, J Aronowski, J Astrup, J Bai, J Inserte, J Johnsen, JC Wang, JE Jung, JL Saver, JM Vicencio, John Cunningham, JP Audia, JPG Sluijter, JS Balami, JV McGowan, K Szummer, KL Furie, L Zhang, M Fisher, M Gharanei, M Gharanei, M Schmidt, M Thielmann, Malcolm Walker, Marlene Wiart, Maryna V. Basalay, MD Ginsberg, Michel Ovize, MV Cohen, N Nighoghossian, P Kleinbongard, P Meybohm, PA Lapchak, PA Lapchak, Petra Kleinbongard, R Bell, R Bonita, R Chung, R Madonna, RA Kloner, Richard D. Carr, RM Bell, RM Bell, Robert M. Bell, RR Liu, RR Moustafa, S Lecour, S Pundik, SA Crone, Sandrine Lecour, Sapna Arjun, Sean M. Davidson, SI Savitz, SM Davidson, SM Davidson, SM Davidson, SM Davidson, SP Jones, TA Zelniker, VE O’Collins, VE O’Collins, VL Feigin, W Li, X Rossello, X Rossello, X Xu, Y Li, Z Vermeulen   +117 more
core   +6 more sources

Low Hospital Resource Utilization in Mechanical Thrombectomy for Pulmonary Embolism [PDF]

, 2022
Matthew C. Bunte
openalex   +1 more source

Vascular tortuosity in endovascular mechanical thrombectomy

Brain Circulation, 2021
Endovascular mechanical thrombectomy effectively removes occlusive thrombi from the arterial lumen; however, there is little literature supporting the relevance of vascular geometry on surgical outcomes. Critical vessel characteristics including the degree of angulation and tortuosity influence the ability to advance stent ...
Jeffrey Farooq, Jea Young Lee
openaire   +4 more sources

Neuroprotective Nanoplatform Integrating Antioxidant MXene Nanozymes and Ferroptosis Inhibitors for Targeted Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Cerebral ischemia‐reperfusion injury (CIRI) is a key pathological process limiting the efficacy of stroke therapy. This study has developed an innovative, multifunctional, brain‐targeted nanoplatform (RFP) containing MXene nanoenzymes and ferroptosis inhibitors.
Lu Wang, Chao Hou, Shuo Li, Lizhi Yang, Yiqun Lin, Sen Wang, Xiaohua Jia, Hui Hui, Wen He, Wei Zhang   +9 more
wiley   +1 more source