Results 121 to 130 of about 26,764 (250)

Toosendanin Alleviates Cerebral Ischemia/Reperfusion Injury via Inhibiting Neural Ferroptosis Through Lipid Metabolic Reprogramming in MCAO Mice

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Post‐stroke administration of TSN significantly reduced infarct volume, neuroinflammation, and improved functional recovery of MCAO mice. TSN alleviated neural oxidative stress, lipid peroxidation, and ferroptosis in MCAO mice. TSN modulated the infiltration of immune cells in MCAO mice in vivo and T cell differentiation in vitro.
Xinyun Li, Zhiyong Zhao, Jingting Zhao, Xiangming Ye, Zhenfei Xiong, Jiejin Zhao   +5 more
wiley   +1 more source

Mechanical behavior of rf -treated thrombus in mechanical thrombectomy

, 2017
Intra-arterial mechanical thrombectomy (IAMT) treatments for ischemic stroke have higher recanalization rate, longer treatment time window and lower risk of symptomatic intracerebral hemorrhage (sICH).
Chi Hang Chon, David CC Lam, John CK Kwok, Qin, Zhen, Zhen Qin, Lam, David CC, Chon, Chi Hang, Kwok, John CK   +7 more
core   +1 more source

Neuroprotective Effects of Phenothiazines on Acute Ischemic Stroke

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
For acute ischemic stroke due to large vessel occlusion, adjunctive neuroprotective therapy with mechanical thrombectomy is important; however, current treatment options are relatively limited. Phenothiazines such as chlorpromazine and promethazine (C + P) have shown potential neuroprotective effects in preclinical studies.
Qi Wang, Weili Li, Di Wu, Shuaili Xu, Xunming Ji   +4 more
wiley   +1 more source

Treating hemodialysis access thrombosis with the InThrill Thrombectomy System: Technique and case report

Radiology Case Reports
The purpose of this report is to describe via a case example an efficient mechanical thrombectomy technique for hemodialysis access thrombosis using the InThrill Thrombectomy System (Inari Medical, Irvine, CA).
Luke Wright, MD, Dan Schneider, MEd
doaj   +1 more source

Pharmacokinetics and Neuroprotective Efficacy of Poly‐Arginine Peptide R18D in Sprague Dawley Rats Subjected to Transient Intraluminal Filament Middle Cerebral Artery Occlusion Stroke

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
The R18D peptide exhibits a favorable pharmacokinetic profile and significantly reduces infarct volume in a rat model of middle cerebral artery occlusion (MCAO) followed by reperfusion. These findings highlight the potential clinical utility of R18D as a neuroprotective therapy for stroke patients undergoing endovascular recanalization interventions ...
Bruno P. Meloni, Stuart K. Gribble, Meghan G. Thomas, Ayelet Weksler, Lena Finkelstein, Lena Fishtein, Dimitry Kovalchuk, Gilad Maximov, Avital Schauder, Keren Kigel‐Zur, Sigal Meilin   +10 more
wiley   +1 more source

The correlation of whole blood viscosity and outcome in mechanical thrombectomy for acute ischemic stroke

Frontiers in Stroke
IntroductionWhole blood viscosity (WBV), reflecting the intrinsic resistance of blood flow, is an established predictor of stroke events in individuals.
Monika Thapa, Jordyn Courville, Reese Leonhard, Prabandh Buchhanolla, Mohammad Abdurrehman Sheikh, Rahul Shah, Prashant Rai, Himanshu Chokhawala, Md Ismail Hossain, Mohammad Alfrad Nobel Bhuiyan, J. Dedrick Jordan, Roger E. Kelley   +11 more
doaj   +1 more source

Serum Uric Acid as a Sex‐Dependent Risk Marker of Post‐Stroke Epilepsy After Acute Ischemic Stroke: Complementary Mendelian Randomization and Cohort Analyses

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
In 21,459 acute ischemic stroke patients, Mendelian randomization found no shared genetic causal link between serum uric acid and epilepsy. Elevated admission uric acid was a robust risk marker for post‐stroke epilepsy in women but not men, with the apparent male protective association sensitive to stratification method.
Yan Cheng, Ji Li, Yunzhou Yang
wiley   +1 more source

Endovascular Mechanical Thrombectomy for Ischemic Stroke Treatment in the Setting of Aortic Dissection: Case Report

Case Reports in Neurology
Introduction: Acute ischemic stroke can occur in the setting of aortic dissection. Information concerning the utility of endovascular mechanical thrombectomy as an intervention for patients with aortic dissection who are experiencing an acute stroke due ...
Luis Alberto Cruz-Saavedra, Jeet Patel, Daniel Siragusa, Scott L. Silliman   +3 more
doaj   +1 more source

Convulsive‐Like Movements in Posterior Circulation Large Vessel Occlusion: Associations With Midbrain Injury and Poor Outcome

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Graphical abstract illustrating the association between convulsive‐like movements, midbrain injury, and unfavorable 90‐day functional outcome in posterior circulation large vessel occlusion (LVO). ABSTRACT Background and Purpose Convulsive‐like movements are an uncommon and frequently misinterpreted manifestation of posterior circulation stroke ...
Wan Wang, Juntao Yin, Boyi Yuan, Zixin Wang, Jiamin Li, Yun Chen, Jiameng Li, Xinyi Wang, Jiapeng Zhao, Jinming Sheng, Qingfeng Ma   +10 more
wiley   +1 more source

Relationship Between Baseline Infarct and Clinical Outcome in Pediatric Large‐Vessel Occlusion Ischemic Stroke

Stroke: Vascular and Interventional Neurology
Background In adults with large‐vessel occlusion stroke, the extent of the baseline infarct measured using the Alberta Stroke Program Early Computed Tomography Score (ASPECTS) predicts outcome and is used during patient selection for mechanical ...
Kartik D. Bhatia, Carmen Parra‐Farinas, Elizabeth Pulcine, Nomazulu Dlamini, Ian Andrews, Sachin Gupta, Richard Webster, Christopher Troedson, Russell C. Dale, John Worthington, Kylie Tastula, Timothy Ang, Andrew Cheung, Nathan Manning, Ferdinand Miteff, Christina Miteff, Prakash Muthusami   +16 more
doaj   +1 more source