Results 141 to 150 of about 2,429,653 (258)

Age Is an Effect Modifier of Thrombectomy Benefit in a Socioeconomically Vulnerable Stroke Population

Annals of Neurology, Volume 100, Issue 3, Page 644-652, September 2026.
Objective Randomized trials from high‐income countries have shown that endovascular treatment (EVT) yields similar benefits in elderly and non‐elderly patients with large vessel occlusion stroke (LVOS). However, evidence from low/middle‐income countries remains scarce.
Fabricio O. Lima, Francisco José de A. Mont'Alverne, Letícia C. Rebello, Daniel G. Abud, Gisele S. Silva, Michel E. Frudit, Mário B. Wagner, Jamary Oliveira‐Filho, Diogo C. Haussen, David S. Liebeskind, Octávio M. Pontes‐Neto, Norberto A.F. Frota, Guilherme Dabus, Gabriel R. de Freitas, Adson F. de Lucena, Jeffrey L. Saver, Raul G. Nogueira, Sheila C.O. Martins, for the RESILIENT Trial Investigators   +18 more
wiley   +1 more source

Trends and Disparities in Aspiration Pneumonitis Mortality With Co‐Listed Stroke Among US Adults, 1999–2024: A CDC WONDER Analysis

Brain and Behavior, Volume 16, Issue 9, September 2026.
National mortality from aspiration pneumonitis with co‐listed stroke declined substantially among US adults from 1999–2024. However, persistent disparities by sex, age, race/ethnicity, region, and rurality, together with rising mortality in younger adults, highlight the need for equitable stroke prevention, dysphagia surveillance, and poststroke ...
Mirza Ammar Arshad, Shiza Talib Butt, Wahhaj Munir, Muhammad Hassan Daniyal, Rohan Ahmad Daud, Warda Ikram, Rijas Ramish, Isbah Aman, Maryam Aslam, Hafiz Ahmad Masood, Asad Ali Ahmed Cheema   +10 more
wiley   +1 more source

Association of Hospital Volume With Outcomes of Pulmonary Embolism in the United States

Catheterization and Cardiovascular Interventions, Volume 108, Issue 3, Page 890-898, September 1, 2026.
ABSTRACT Background Pulmonary embolism (PE) remains a leading cause of mortality in the United States. While prior studies show improved outcomes at higher‐volume centers, the understanding of procedural utilization remains limited. Aims Therefore, this study aimed to evaluate the association of hospital PE volume and intervention utilization with ...
Zihan Gao, Troy N. Coaston, Sidney Hinks, Nida Qadir, Obi Emeruwa, Peyman Benharash   +5 more
wiley   +1 more source

Mechanical Thrombus Aspiration for a Young STEMI Patient With Plaque Erosion: Time for a Stent‐Free Approach?

Catheterization and Cardiovascular Interventions, Volume 108, Issue 3, Page 833-839, September 1, 2026.
ABSTRACT A 34‐year‐old man with no cardiovascular history presented with anterior ST‐elevation myocardial infarction and a large thrombotic occlusion of the mid left anterior descending artery. Following potent antithrombotic therapy and mechanical thrombus aspiration, angiography revealed vessel patency without residual significant stenosis, allowing ...
Domenico Simone Castiello, Francesco Greco, Antonio Curcio, Alberto Polimeni   +3 more
wiley   +1 more source

Thrombus Metabolism‐Based Molecular Subtyping for Prognostic Risk Stratification in Acute Ischemic Stroke: A Preliminary Study

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
This study identified two metabolically distinct thrombus molecular subtypes in AIS: a lipid metabolism‐enriched subtype (C1) associated with cardioembolic stroke and poor functional outcomes, and a folate metabolism‐enriched subtype (C2) linked to atherothrombotic stroke and better prognosis. A six‐metabolite signature further demonstrated exploratory
Taoyuan Lu, Wei Li, Wenbo Cao, Yiying Liu, Jinzi Wei, Dechao Wang, Liqun Jiao, Xin Xu   +7 more
wiley   +1 more source

Exercise‐Induced Myonectin Protects Against Cerebral Ischemia–Reperfusion Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Exercise‐induced myonectin protects against cerebral ischemia–reperfusion injury. Myonectin knockout abolishes exercise benefits, whereas recombinant administration reduces cerebral infarct size. Mechanistically, myonectin activates PI3K/AKT/mTOR signaling, thereby suppressing excessive neuronal autophagy and microglial‐driven neuroinflammation ...
Jing Zhang, Shengle Chen, Jingyu Liu, Xin Qi, Xiaoming Zhang, Peng Lin, Dezhang Huang, Jing Li   +7 more
wiley   +1 more source

Investigation of the Mechanism of Total Flavonoids From Chuju in Mitigating Cerebral Ischemia–Reperfusion Injury in Rats Using Untargeted Metabolomics

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Total flavonoids of Chuju (TFCJ) protect against cerebral ischemia–reperfusion injury (CIRI) in rats by reducing infarct volume, alleviating oxidative stress, and regulating metabolic pathways including the TCA cycle, glycolysis, pentose phosphate pathway (PPP), and aspartate–glutamate metabolism.
Guanglei Zhang, Zongmeng Zhang, Cong Wang, Gaocheng Shi, Mengqi Zhao, Xianxi Wu, Xiaoyong Yuan, Hao Yu   +7 more
wiley   +1 more source

Beyond the Black Box: Is Artificial Intelligence Ready to Reshape Neurosurgical Decision‐Making? A Narrative Review

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Artificial intelligence (AI) is increasingly being integrated into neurosurgical practice, offering capabilities in diagnostic imaging, surgical planning, and outcome prediction. However, the “black box” nature of many AI systems generating recommendations without a transparent rationale poses fundamental challenges to ...
Dip Bahadur Singh, Yashoda Dangi, Bhishma Prasad Pokharel   +2 more
wiley   +1 more source

From Negative Duplex to Phlegmasia in Minutes: Bedside POCUS Identifies Rapid Thrombosis Unmasking Underlying May–Thurner Syndrome

Journal of Clinical Ultrasound, Volume 54, Issue 7, Page 1799-1803, September 2026.
Point‐of‐care‐ultrasound revealed an evolving acute noncompressible deep vein thrombosis (asterisks) in the left lower extremity veins (right panel) that was not evident on duplex ultrasound 14 min prior (left panel; asterisks demonstrate compressed veins). The patient was treated emergently and found to have May–Thurner syndrome.
Anthony Unger
wiley   +1 more source

Mechanical thrombectomy for acute ischemic stroke

, 2016
The overall aim of this doctoral thesis was to study the outcome and safety of mechanical thrombectomy, which is an endovascular technique for treating moderate to severe acute ischemic stroke caused by a large cerebral artery occlusion.
Åsa Kuntze Söderqvist (18661648)
core   +1 more source