Results 131 to 140 of about 2,602,339 (340)

Tenecteplase Versus Alteplase for First‐Pass Reperfusion in Basilar Artery Occlusion Stroke Thrombectomy

Annals of Neurology, EarlyView.
Objective The first‐pass effect (FPE), defined as excellent reperfusion after a single attempt, is associated with improved outcomes in large vessel occlusion stroke. We evaluated whether intravenous tenecteplase (TNK) compared with alteplase (TPA) increases the likelihood of FPE in basilar artery occlusion (BAO).
Dylan N. Wolman, Rahul R. Karamchandani, Sina Hemmer, Tyler M. Bielinski, Nitin Goyal, Jeremy B. Rhoten, Mahesh V. Jayaraman, Christian T. Sidebottom, Bradley A. Gross, Alhamza R. Al‐Bayati, Mohamed F. Doheim, Matthew K. Tobin, Anoop Chinthala, Avi Gajjar, Justin Mascitelli, Matthew R. Webb, Jan‐Karl Burkhardt, Kyle W. Scott, Visish Srinivasan, Daniel Tonetti, Manisha Koneru, David J. Altschul, Dhrumhil Vaishnav, Sumeet Multani, Thana Theofanis, William J. Ares, Je Yeong Sone, Ramin Zand, Sasan Bahrami, Jiang Li, Gary Defilipp, Dale Strong, Radmehr Torabi, Krisztina Moldovan, Clemens M. Schirmer, Alexandra R. Paul, Bradley N. Bohnstedt, Raul G. Nogueira, Philipp Hendrix   +38 more
wiley   +1 more source

Recent advances in intra-arterial thrombolysis

Annals of Indian Academy of Neurology, 2008
Thrombolytic therapy has revolutionized acute ischemic stroke (AIS) treatment; however it is clear that intravenous (IV) thrombolytic therapy has certain limitations, including a short-time window for use, poor specificity for the site of arterial ...
Bershad Eric, Suarez Jose
doaj  

A Brief Review on Failed Hybrid Treatment for Massive Pulmonary Embolism: Catheter-Directed Thrombolysis (CDT) and Pharmaco-Mechanical Thrombolysis (PMT). [PDF]

Curr Probl Cardiol, 2022
Cueto-Robledo G, Rivera-Sotelo N, Roldan-Valadez E, Narvaez-Oriani CA, Cueto-Romero HD, Gonzalez-Hermosillo LM, Hidalgo-Alvarez M, Barrera-Jimenez B.   +7 more
europepmc   +1 more source

Revisiting Incomplete Tissue‐Level Reperfusion Following Successful Thrombectomy for Acute Ischemic Stroke

Annals of Neurology, EarlyView.
Among patients with acute ischemic stroke achieving successful large vessel recanalization (defined as expanded Thrombolysis in Cerebral Infarction [eTICI ≥2b]), incomplete tissue‐level reperfusion, distinct from visually identifiable distal occlusion on digital‐subtraction angiography, remains a significant challenge.
Yue Qiao, Adrien Ter Schiphorst, Yi Xu, Jean‐Claude Baron, Wenbo Zhao   +4 more
wiley   +1 more source

Oral anticoagulants - a frequent challenge for the emergency management of acute ischemic stroke [PDF]

, 2012
Background: The emergency management of patients with acute ischemic stroke (IS) using oral anticoagulants (OAC) represents a great challenge. Effective anticoagulation predisposes to bleeding and represents a contraindication for systemic thrombolysis ...
Gumbinger, Christoph, Hacke, Werner, Horstmann, Solveig, Jenetzky, Ekkehart, Möhlenbruch, Markus, Ringleb, Peter, Rizos, Timolaos, Spindler, Marcia, Veltkamp, Roland   +8 more
core   +1 more source

Endovascular treatment of acute ischemic stroke with large vessel occlusion: history, present and future

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Five randomized control clinical trials of N Engl J Med showed the efficacy of endovascular treatment (EVT) of acute ischemic stroke with large vessel occlusion (AIS ⁃ LVO) of anterior circulation. The "spring" of mechanical thrombectomy is coming.
Zhong⁃rong MIAO, HUO Xiao⁃chuan
doaj  

Impact of catheter fragmentation followed by local intrapulmonary thrombolysis in acute high risk pulmonary embolism as primary therapy

Indian Heart Journal, 2014
Background: Pulmonary embolism (PE) with more than 50% compromise of pulmonary circulation results significant right ventricular (RV) afterload leading to progressive RV failure, systemic hypotension and shock.
Bishav Mohan, Naved Aslam, Anil Kumar Mehra, Shibba Takkar Chhabra, Praneet Wander, Rohit Tandon, Gurpreet Singh Wander   +6 more
doaj   +1 more source

Coagulation-monitored, dose-adjusted catheter-directed thrombolysis or pharmaco-mechanical thrombus removal in deep vein thrombosis

, 2023
Julian Kleine Wortmann, Stefano Barco, Riccardo M. Fumagalli, Davide Voci, Ulrike Hügel, Rahel Vera Cola, David Spirk, Nils Kucher, Tim Sebastian   +8 more
openalex   +1 more source

DNase1 RS1053874 Polymorphism is Associated with Early Neurological Recovery through NET Modulation and with Long‐Term Survival in Ischemic Stroke: A Prospective Cohort Study

Annals of Neurology, EarlyView.
Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito, P. Calleja, L. Alzamora, A. Ruiz‐García, A. Martínez‐Salio, M. Muñoz‐García, F. Ostos, A. García‐Culebras, A. Moraga, M.A. Moro, I. Lizasoain   +10 more
wiley   +1 more source

Indications for Catheter-Directed Thrombolysis in the Management of Acute Proximal Deep Venous Thrombosis [PDF]

, 2010
Deep vein thromboses (DVTs) cause significant morbidity and mortality in the general population. Oral anticoagulation therapy may reduce thrombus propagation but does not cause clot lysis and therefore does not prevent postthrombotic syndrome (PTS ...
Hinchliffe, R, Holt, PJ, Loftus, IM, Patterson, BO, Thompson, MM   +4 more
core   +1 more source