Results 61 to 70 of about 39,447 (248)

Shaken and Stirred: Mechanisms of Ultrasound-Enhanced Thrombolysis [PDF]

Ultrasound in Medicine & Biology, 2015
The use of ultrasound and microbubbles as an effective adjuvant to thrombolytics has been reported in vitro, ex vivo and in vivo. However, the specific mechanisms underlying ultrasound-enhanced thrombolysis have yet to be elucidated. We present visual observations illustrating two mechanisms of ultrasound-enhanced thrombolysis: acoustic cavitation and ...
Kenneth B, Bader, Matthew J, Gruber, Christy K, Holland   +2 more
openaire   +2 more sources

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

Predictors for cerebral edema in acute ischemic stroke treated with intravenous thrombolysis [PDF]

, 2017
Cerebral edema (CED) is a severe complication of acute ischemic stroke. There is uncertainty regarding the predictors for the development of CED after cerebral infarction.
Ahmed, Niaz, Azevedo, Elsa, Dawson, Jesse, Egido, Jose A., Falcou, Anne, Ford, Gary A., Holmin, Staffan, Mikulik, Robert, Ollikainen, Jyrki, Thorén, Magnus, Wahlgren, Nils   +10 more
core   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

A Steerable and Expandable Magnetic Aspiration Catheter for Enhanced Aspiration Thrombectomy

Advanced Intelligent Systems, EarlyView.
This article presents a novel magnetic aspiration catheter (MAC) that can be both actively steered and undergo distal‐end expansion via externally applied magnetic fields. The MAC facilitates precise branch selection and enhances clot engagement by improving endovascular navigation and aspiration efficiency. Phantom experiments validate its feasibility
Hakjoon Lee, Xiao Dong, Dong‐in Kim, A. M. Masum Bulbul Chowdhury, Nader Latifi Gharamaleki, Jin‐young Kim, Sung Won Youn, Hongsoo Choi   +7 more
wiley   +1 more source

Predicting Bleeding and Thrombosis Complications in Patients with Continuous Flow Left Ventricular Assist Devices [PDF]

, 2020
Background: Left ventricular assist device (LVAD) therapy has been proven to relieve heart failure symptoms and improve survival, but is not devoid of bleeding and/or thrombotic complications.
Cook, Aaron, Kuan, William, McCann, Justin McCann, Parli, Sara, Schadler, Aric, Sieg, Adam, Zacholski, Kyle   +6 more
core   +1 more source

Mechanical Thrombolysis and Stenting in Acute Ischemic Stroke [PDF]

Stroke, 2012
Acute ischemic stroke is one of the major sources of morbidity and mortality in the industrialized countries. The lifetime risk of stroke is estimated to be 1 in 5 for middle-aged women and 1 in 6 for men according to the Framingham Study.1 Outcome depends on the length of time between onset of symptoms and revascularization, the recanalization rate ...
Jan, Gralla, Caspar, Brekenfeld, Pasquale, Mordasini, Gerhard, Schroth   +3 more
openaire   +2 more sources

Liquid Jetting‐Based Miniature Robotic Navigation in Confined Fluidic Spaces

Advanced Intelligent Systems, EarlyView.
We introduce a new class of liquid‐jetting‐based miniature robots (JetBots) ranging in size from mm‐to‐cm, featuring a unified approach in design, fabrication, and actuation. They demonstrate fast locomotion (30.3 cm/s), rapid steering (648.8°/s), and diverse functions, such as puncturing soft materials and unlimited cargo sampling and delivery, paving
Debasish Roy, Tianlu Wang
wiley   +1 more source

Treatment of the acute severe pulmonary embolism using endovascular methods [PDF]

, 2018
Purpose: To present a single-centre experience with endovascular treatment of patients with severe symptoms secondary to acute pulmonary embolism (PE). Material and methods: Twenty-five patients were treated due to contraindications or deficient effects ...
Bursjoo, Carina, Cwikiel, Wojciech, Keussen, Inger E.   +2 more
core   +1 more source

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

Animal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao, Chunlan Zou, Junxian Li, Yang Yang, Yuanyuan Han, Tingyu Ke   +5 more
wiley   +1 more source