Results 61 to 70 of about 2,607,441 (255)

Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST) [PDF]

, 2008
<p><b>Background and Purpose:</b> The Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST) unadjusted results demonstrated that intravenous alteplase is well tolerated and that the effects were comparable with ...
Wahlgren, N., Dávalos A, Hennerici MG, Kaste, M., N. Eriksson, Toni, Danilo, Bluhmki, Erich, N. Wahlgren, Hacke, Werner, Köhrmann, Martin, M. Kaste, Eriksson, Niclas, Aichner F, Ahmed N, Hacke W, Eriksson, N., Koehrmann, M., Bluhmki E, Grond M, F. Aichner, V. Larrue, G. A. Ford, D. Toni, Kaste M, Larrue, Vincent, Erila, T., Larrue, V., Eriksson, Niclas,, Aichner, F., M. G. Hennerici, Wahlgren, Nils, Davalos, A., Ford, Gary A, Grond, M., Toni, D., K. R. Lees, null null, Hennerici, Michael G, T. Erila, Roine, Risto O, Hacke, W., Koehrmann, Martin, Davalos, Antoni, Eriksson N, W. Hacke, Larrue V, Erilä, Terttu, A. Davalos, Aichner, Franz, Bluhmki, E., Wahlgren N, Roine RO, Machnig, T., M. Grond, Vanhooren, Geert, Ford, G.A., Roine, R.O., Hennerici, Michael G., Lees, K.R., Roine, Risto O., E. Bluhmki, Hennerici, M.G., Lees KR, Grond, Martin, Kaste, Markku, Köhrmann M, Peeters, André, Ahmed, Niaz, Machnig, Thomas, Machnig T, Vanhooren G., Erilä T, M. Kohrmann, Ahmed, N., R. O. Roine, Lees, Kennedy R., Ford GA, G. Vanhooren, Vanhooren, G., Lees, Kennedy R, Ford, Gary A., T. Machnig, N. Ahmed, Grond, M, Aichner, F, Erila, T, Hacke, W, Davalos, A, Eriksson, N, Ford, GA, Ahmed, N,, Bluhmki, E, Wahlgren, N   +92 more
core   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Pulmonary Embolism in COVID-19 Treated with VA-ECLS and Catheter tPA

Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2020
Background: Novel coronavirus 2019 (COVID-19) has been the focus of the medical world since being declared a pandemic in March 2020. While the pathogenesis and heterogeneity of COVID-19 manifestations is still not fully understood, viral evasion of ...
Arda Akoluk, Usman Mazahir, Steven Douedi, Adel Aziz, Aref Obagi, Daniel Kiss, Daniel Flynn, Eric Costanzo, Sinan A Simsir, Matthew D Saybolt   +9 more
doaj   +1 more source

Thrombolysis Through Punctured Coronary Balloon and 014 Wire Mediated Guitaring After IVC Filter Insertion in Iliofemoral Deep Vein Thrombosis

European Journal of Case Reports in Internal Medicine, 2023
This is a report of a patient who presented with iliofemoral deep vein thrombosis, and was treated with pharmaco-invasive and pharmaco- mechanic methods using coronary balloon and mechanical disruption of clots with coronary 014 wire.
Mark Christopher Arokiaraj
doaj   +1 more source

Direct Mechanical Intervention Versus Bridging Therapy in Stroke Patients Eligible for Intravenous Thrombolysis: A Pooled Analysis of 2 Registries. [PDF]

, 2017
BACKGROUND AND PURPOSE Randomized controlled trials have shown that mechanical thrombectomy (MT) plus best medical treatment improves outcome in stroke patients with large-vessel occlusion in the anterior circulation.
Sarikaya, Hakan, Arnold, Marcel, Dobrocky, Tomas, Chapot, René, Sebastian Bellwald, Gralla, Jan, Fischer, Urs, Berger, Klaus, Mono, Marie-Luise, Bellwald, Sebastian, Christian P. Stracke, Urs Fischer, Hannes Nordmeyer, Stracke, Christian P, Weber, Ralph, Mordasini, Pasquale, Simon Jung, Bernasconi, Corrado Angelo, Ralph Weber, Jung, Simon, Hadisurya, Jeffrie, Jeffrie Hadisurya, Hakan Sarikaya, Marie-Luise Mono, Nordmeyer, Hannes, Pasquale Mordasini, Klaus Berger, Corrado Bernasconi, Jan Gralla, Tomas Dobrocky, Marcel Arnold, René Chapot, Dobrocky T, Chapot R, Fischer U, Hadisurya J, Mordasini P, Mono ML, Stracke CP, Berger K, Bernasconi C, Arnold M, Bernasconi, Corrado, Nordmeyer H, Stracke, Christian P., Bellwald S, Gralla J, Sarikaya H, Jung S, Weber R   +49 more
core   +1 more source

Cell‐Based Biohybrid Micro/Nanorobots for Biotherapy

Advanced Robotics Research, EarlyView.
This review systematically evaluates cell‐based biohybrid micro/nanorobots (CB‐BMRs), highlighting their cell selection criteria, fabrication strategies, and diverse actuation modes. Furthermore, it surveys the promising therapeutic applications of CB‐BMRs in targeted cancer, thrombosis, and inflammation treatments, while comprehensively discussing ...
Lin Wang, Chenlu Liu, Yu Zhao, Chuanhua Li, Xuyang Chen, Shixiao Ding, Lizhou Dai, Guokun Wang, Tianlong Li, Jiaxin Li, Xuejia Liu, Haocheng Wang   +11 more
wiley   +1 more source

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

Advanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu, Xinkui Liu, Nannan Fan, Xiaoyan Yu, Qiaoqiao Han, Yunhong Zhang, Wei Li, Yongqing Cai, Miaomiao Zhou, Fang Li, Feifei Shi, Zhen Zhang, Bin Wang, Xia Li   +13 more
wiley   +1 more source

Chinese stroke association guidelines on reperfusion therapy for acute ischaemic stroke 2024

Stroke and Vascular Neurology
Background Stroke remains a major global health challenge, with China experiencing a significant burden due to its high incidence and severe outcomes.
, Liping Liu, Anding Xu, Xin Wang, Yongjun Wang, Yilong Wang, Zhongrong Miao, Yuming Xu, Benyan Luo, Bin Peng, Yong Huo, Qiang Dong, Zixiao Li, Xingquan Zhao, Caiyun Wang, Hongqiu Gu, Chunjuan Wang, Zhengqi Lu, Yunyun Xiong, Shuo Wang, Lihua Wang, Linong Ji, Xiaoping Gao, Wenzhi Wang, Yi Yang, Kai Wang, Junbo Ge, Xunming Ji, Jun Pu, Tong Zhang, Bo Hu, Ning Wang, Yun Xu, Jinsheng Zeng, Gang Zhao, Zhong Chen, Aoming Jin, Xiaoyuan Niu, Jiong Shi, Shuya Li, Jianmin Zhang, Ling Yin, Dou Li, Dehong Lu, Chao Qin, Dapeng Sun, Kaifu Ke, Yanhui Du, Xiaoning Zhang, Fudong Shi, Jianxin Zhou, Lan Chu, Li Guo Li He, Shengnian Zhou, Weixin Cai, Xiaomu Wu, Zhiyi He   +56 more
doaj   +1 more source

β‐Adducin Restrains PLA2G4A‐Dependent Lysosomal Membrane Permeabilization and Neuronal Death in Ischemic Stroke

Advanced Science, EarlyView.
This study identifies β‐adducin as a regulator of lysosomal integrity in ischemic neurons. Ischemia‐associated FTO loss increases m6A modification and destabilizes Add2 mRNA, reducing β‐adducin expression and promoting PLA2G4A accumulation at lysosomes.
Hui‐qin Li, Pin‐yi Liu, Dan Wu, Fei‐yu Ma, Yi Bai, Sheng‐nan Xia, Hai‐yan Yang, Xin‐yu Bao, Yun Xu, Xiang Cao   +9 more
wiley   +1 more source

Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning

Advanced Science, EarlyView.
Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin, Jian Lyu, Yanci Liu, Zhiyuan Feng, Jie Bao, Wenxiong Song, Bingcheng Zhu, Minghao Liu, Jionghao Xue, Jiadi Weng, Jiani Zhang, Jizong Zhao, Xiaolin Chen, Bin Dong   +13 more
wiley   +1 more source