Results 81 to 90 of about 2,607,441 (255)

Zero anticoagulation, zero thrombolysis: successful management of massive pulmonary embolism following hemorrhagic transformation of acute ischemic stroke: a case report

Frontiers in Cardiovascular Medicine
BackgroundThe treatment of patients with severe pulmonary embolism complicated by intracerebral hemorrhage is challenging: anticoagulation or thrombolysis, essential for treating pulmonary embolism, can substantially worsen intracranial hemorrhage and ...
Zengkai Xu, Bing Ding, Jiahuang Wu, Hongjin Wang, Zeping Chen, Zhisheng Wang   +5 more
doaj   +1 more source

Thrombolysis in Childhood Stroke. Report of 2 Cases and Review of the Literature

, 2009
BACKGROUND AND PURPOSE: No controlled, randomized trial has investigated whether intravenous, intra-arterial (IAT), or mechanical thrombolysis is beneficial in children with ischemic stroke.
Arnold, Marcel, Moser, S J, Mono, M L, Schroth, G, Mattle, H P, Steinlin, M, Schroth, Gerhard, Remonda, Luca, Baumann, Andreas, Arnold, M, Mono, Marie-Luise, Baumgartner, R W, Nedeltchev, Krassen, Baumann, A, Baumgartner, Ralf W, Steinlin, Maja, Moser, Sonya Jourdan, Mattle, Heinrich P, Nedeltchev, K, Remonda, L, Arnold M, Baumgartner, Ralf W., Mattle, Heinrich P., Baumgartner RW, Baumann A, Nedeltchev K, Moser SJ, Mattle HP, Steinlin M, Mattle, Heinrich, Remonda L, Mono ML, Schroth G   +32 more
core   +1 more source

Benchmarking local practice in view of introduction of thrombolysis for stroke in Malta [PDF]

, 2015
The aim of the study was to benchmark the quality of local stroke care in view of introduction of thrombolysis. Stroke patients admitted to Mater Dei Hospital over 6 weeks in 2008 were recruited.
Vella, Norbert, Azzopardi, Laura, Galea Debono, Anthony, Dingli, Philip, Vassallo, Diana, Aquilina, Josanne, Micallef, Daniel (2015), Mallia, Maria   +7 more
core  

Risk factors for hemorrhage during local intra-arterial thrombolysis for lower limb ischaemia

, 2011
Assessment of clinical risk factors for haemorrhagic complications in patients undergoing intra-arterial thrombolysis for lower limb ischaemia. Retrospective reviews of consecutive patients subjected to intra-arterial thrombolysis due to lower limb ...
Kuoppala, Monica,, Svensson, Peter,, Franzén, Sofia,, Lindblad, Bengt,, Acosta, Stefan,, Åkeson, Jonas,, Lund University.   +6 more
core   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Single‐Cell RNA Sequencing and Spatial Multiomics Unveil Microglia–Mural Interactions Underlying Notoginsenoside R1 Against Ischemic Stroke

iMetaMed, EarlyView.
Integrated scRNA‐seq and spatial multiomics provide single‐cell and spatial insights into the neuroprotective effects of NGR1, a clinically validated bioactive compound from Panax notoginseng. NGR1 was associated with a shift in microglial transcriptional states away from ischemia‐associated pro‐inflammatory Adam8hi microglia and toward the protective ...
Qikun Zhao, Wenbo Guo, Yanrong Zheng, Guoqian Cui, Bingjie Wan, Shuhui Deng, Hudong Bao, Xiao Tu, Shengshuang Chen, Jie Liao, Xiaohui Fan   +10 more
wiley   +1 more source

A Brief Review on Failed Hybrid Treatment for Massive Pulmonary Embolism: Catheter-Directed Thrombolysis (CDT) and Pharmaco-Mechanical Thrombolysis (PMT). [PDF]

Curr Probl Cardiol, 2022
Cueto-Robledo G, Rivera-Sotelo N, Roldan-Valadez E, Narvaez-Oriani CA, Cueto-Romero HD, Gonzalez-Hermosillo LM, Hidalgo-Alvarez M, Barrera-Jimenez B.   +7 more
europepmc   +1 more source

Phenotypic and Genotypic Analysis of Two Rare Cases of ‐‐SEA/‐α4.3 HbH Disease

Journal of Clinical Laboratory Analysis, EarlyView.
We report two unrelated adult patients with rare deletional HbH disease (genotype ‐‐SEA/‐α4.3). This novel 4.3 kb deletion covering the HBA1 gene is accompanied by X‐Y‐Z segment recombination, which was identified by CycloneSEQ long‐read nanopore sequencing.
Weijia Yang, Xiaoyan Huang, Li Zhang, Xiaoqin Yang, Yaya Guo, Qingping Kang, Min Dou, Guijun Huang   +7 more
wiley   +1 more source

Effect of mechanical thrombectomy alone or in combination with intravenous thrombolysis for acute ischemic stroke

, 2018
Whether combining intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) is superior to mechanical thrombectomy alone for large vessel occlusion acute ischemic stroke is still uncertain.
Konda, Daniel, Diomedi, Marina, Morosetti, Daniele, Koch, Giacomo, Koch G., Gandini, Roberto, Gandini R., Sallustio F., Konda D., Fabiano S., Sallustio, Fabrizio, Diomedi M., Pampana E., Alemseged F., Fabiano, Sebastiano, Alemseged, Fana, Pampana, Enrico   +16 more
core   +1 more source

Kaempferol Attenuates Myocardial Ischemia–Reperfusion Injury by Suppressing Ferroptosis via the KEAP1–Nrf2–GPX4 Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial ischemia/reperfusion (I/R) injury is characterized by cardiomyocyte death, excessive oxidative stress, inflammation, and ferroptosis, which collectively limit the efficacy of reperfusion therapy. In this study, we investigated whether kaempferol (KAE), a natural flavonol with antioxidative and antiinflammatory properties, could ...
Yan‐Bo Zhao, Ling‐Ling Sun, Xiao‐Hua Shen, Min Wang, Mei‐Hui Wang, Lu‐Lu Liu, Kai Zhang   +6 more
wiley   +1 more source