Results 91 to 100 of about 2,607,441 (255)

Recent advances in intra-arterial thrombolysis

Annals of Indian Academy of Neurology, 2008
Thrombolytic therapy has revolutionized acute ischemic stroke (AIS) treatment; however it is clear that intravenous (IV) thrombolytic therapy has certain limitations, including a short-time window for use, poor specificity for the site of arterial ...
Bershad Eric, Suarez Jose
doaj  

Preceding Intravenous Thrombolysis Facilitates Endovascular Mechanical Recanalization in Large Intracranial Artery Occlusion

, 2011
Background and aims Acute occlusions of the large intracranial arteries are relatively resistant to intravenous thrombolysis. Therefore, multimodal approaches combining intravenous thrombolysis with endovascular mechanical recanalization are increasingly
Gunther Fesl, Markus Holtmannspötter, Hartmut Brückmann, Thomas Pfefferkorn, Maximilian Patzig, Christian Opherk, Caroline Ottomeyer, Martin Dichgans   +7 more
core   +1 more source

Terazosin Attenuates Neuronal Pyroptosis by Regulating the Mitochondrial ROS/NLRP3 Inflammasome Axis Through Mitophagy in Cerebral Ischemia–Reperfusion Injury

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cerebral ischemia–reperfusion injury (CI/RI) is a major cause of secondary neuronal damage following ischemic stroke. This study investigated whether terazosin (TZ) exerts neuroprotective effects by regulating mitophagy and the reactive oxygen species (ROS)/NOD‐like receptor protein 3 (NLRP3) inflammasome axis.
Wei Wang, Xin‐Yue Han, Li‐An Huang, Yu‐Sheng Zhang, Heng Meng, An‐Ding Xu   +5 more
wiley   +1 more source

Association Between Triglyceride‐Glucose Index and in‐Hospital Intensive Care Unit Readmission in Ischemic Stroke Patients: A Retrospective Analysis Based on the MIMIC‐IV Database

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This retrospective cohort study utilized the Medical Information Mart for Intensive Care database to investigate the association between the triglyceride–glucose (TyG) index and in‐hospital intensive care unit (ICU) readmission in patients with ischemic stroke (IS). Among 2929 patients, 24.0% experienced ICU readmission.
Di Zhang, Ying‐Lun Chen, Jian Zhang, Xiang‐Jun Hu   +3 more
wiley   +1 more source

Thrombolysis is associated with consistent functional improvement across baseline stroke severity: a comparison of outcomes in patients from the Virtual International Stroke Trials Archive (VISTA) [PDF]

, 2010
<p><b>Background and Purpose:</b> Baseline stroke severity predicts outcomes among thrombolysed patients. The baseline National Institutes of Health Stroke Scale (NIHSS) thresholds are sometimes used to select patients for thrombolysis,
Lees, K.R., Mishra, N.K., Nishant K. Mishra, Kennedy R. Lees, Grotta, J.C., Lyden, P., Patrick Lyden, James C. Grotta   +7 more
core   +1 more source

The Role and Assessment of Lipid Profile in Patients With a Chronic Total Coronary Occlusion

Lipids, EarlyView.
This review summarized evidence on lipid profiles in CTO patients, non‐CTO patients, and healthy individuals, and examined the reported associations between lipid parameters, collateral channel formation, and clinical outcomes. Several key findings emerged from the present study.
Karol Sadowski, Dominika Tomkiel, Roel Hoek, Ruben W. de Winter, Nick S. Nurmohamed, Bimmer E. P. M. Claessen, Niels J. Verouden, Alexander Nap, Sebastiaan A. Kleijn, Mariusz Tomaniak, Yvemarie B. O. Somsen, Paul Knaapen   +11 more
wiley   +1 more source

Endovascular treatment of acute ischemic stroke with large vessel occlusion: history, present and future

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Five randomized control clinical trials of N Engl J Med showed the efficacy of endovascular treatment (EVT) of acute ischemic stroke with large vessel occlusion (AIS ⁃ LVO) of anterior circulation. The "spring" of mechanical thrombectomy is coming.
Zhong⁃rong MIAO, HUO Xiao⁃chuan
doaj  

Carotid Embolectomy and Endarterectomy for Symptomatic Complete Occlusion of the Carotid Artery as a Rescue Therapy in Acute Ischemic Stroke

Case Reports in Neurology, 2011
Emergency endarterectomy of an occluded internal carotid artery (ICA) has not been investigated as an option of rescue therapy for severe acute ischemic stroke in the era of intravenous (IV) thrombolysis treatment neither as a primary treatment nor after
Sami Curtze, Jukka Putaala, Marika Saarela, Pirkka Vikatmaa, Ilkka Kantonen, Turgut Tatlisumak   +5 more
doaj   +1 more source

Stroke Following Facial Laser Resurfacing Procedure—A Case Report

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives To describe the first reported case of embolic stroke with hemorrhagic conversion following a dermatologic energy‐based device procedure, highlighting its mechanism and clinical implications. Methods A detailed case review was conducted, including clinical presentation, imaging, and subsequent diagnostic workup. The patient provided
Tal Levy, Joel L. Cohen
wiley   +1 more source

Correlation of thrombus composition with prognosis of patients with acute cerebral infarction

Di-san junyi daxue xuebao, 2019
Objective To analyze the correlation between thrombus composition and the prognosis of patients with acute cerebral infarction after mechanical thrombectomy.
WANG Suxia, WU Hongchen, WEN Lan
doaj   +1 more source