Results 61 to 70 of about 195,888 (316)

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Grain Refinement and High-Performance of Equal-Channel Angular Pressed Cu-Mg Alloy for Electrical Contact Wire

Metals, 2014
Multi-pass equal-channel angular pressing (EACP) was applied to produce ultrafine-grained (UFG) Cu-0.2wt%Mg alloy contact wire with high mechanical/electric performance, aim to overcome the catenary barrier of high-speed trains by maximizing the tension ...
Aibin Ma, Chengcheng Zhu, Jianqing Chen, Jinghua Jiang, Dan Song, Shizhan Ni, Qing He   +6 more
doaj   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

THE EFFECT OF SEALING PROCESSES ON THE CORROSION BEHAVIOUR OF Al₂O₃-13 WT.%TiO₂ COATING

Ceramics-Silikáty, 2019
A novel post-treatment process was employed to seal a plasma-sprayed Al₂O₃-13wt. %TiO₂ (AT13) coating to improve its corrosion resistance. A series of AT13 coatings were sealed with silicone resin using conventional sealing and ultrasonic sealing at ...
Jia Shao, Zehua Wang, Si Liqiong, Zhou Zehua, Zhang Xin, Jiang Shaoqun, Wang Gang   +6 more
doaj   +1 more source

Damage Modelling of Compressed Earth Blocks Stabilised with Cement

Advances in Civil Engineering, 2022
This work aims at studying the mechanical behaviour of compressed Earth blocks (CEBs) and compressed stabilised Earth blocks (CSEBs) with 4% and 8% in weight cement stabilisation.
Janvier Goutsaya, Guy Edgar Ntamack, Saâd Charif d’Ouazzane   +2 more
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Dealloying-based interpenetrating-phase nanocomposites matching the elastic behavior of human bone

Scientific Reports, 2017
The long-term performance of orthopedic implants depends crucially on a close match between the mechanical behavior of bone and of the implant material. Yet, the present man-made materials with the required biocompatibility and strength are substantially
I. V. Okulov, J. Weissmüller, J. Markmann   +2 more
doaj   +1 more source

Improving Strength and Ductility of a Mg-3.7Al-1.8Ca-0.4Mn Alloy with Refined and Dispersed Al₂Ca Particles by Industrial-Scale ECAP Processing

Metals, 2019
Tailoring the morphology and distribution of the Al2Ca second phase is important for improving mechanical properties of Al2Ca-containing Mg-Al-Ca based alloys.
Ce Wang, Aibin Ma, Jiapeng Sun, Xiaoru Zhuo, He Huang, Huan Liu, Zhenquan Yang, Jinghua Jiang   +7 more
doaj   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Multimodal Microstructure and Mechanical Properties of AZ91 Mg Alloy Prepared by Equal Channel Angular Pressing plus Aging

Metals, 2018
Developing cost-effective magnesium alloys with high strength and good ductility is a long-standing challenge for lightweight metals. Here we present a multimodal grain structured AZ91 Mg alloy with both high strength and good ductility, prepared through
Zhenquan Yang, Aibin Ma, Huan Liu, Jiapeng Sun, Dan Song, Ce Wang, Yuchun Yuan, Jinghua Jiang   +7 more
doaj   +1 more source