Results 61 to 70 of about 933,757 (339)
General Multi-Fidelity Framework for Training Artificial Neural Networks With Computational Models
Frontiers in Materials, 2019 Training of artificial neural networks (ANNs) relies on the availability of training data. If ANNs have to be trained to predict or control the behavior of complex physical systems, often not enough real-word training data are available, for example ...
Roland Can Aydin +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Science and Technology of Advanced MaterialsHydrogels are flexible materials that typically accommodate elongation with positive Poisson’s ratios. Auxetic property, i.e., the negative Poisson’s ratio, of elastic materials can be macroscopically implemented by the structural design of the continuum.
Daisuke Nakagawa, Itsuo Hanasaki
doaj +1 more source
A model for the degradation of polyimides due to oxidation
, 2010 Polyimides, due to their superior mechanical behavior at high temperatures, are used in a variety of applications that include aerospace, automobile and electronic packaging industries, as matrices for composites, as adhesives etc.
C.M. Falcone +25 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Damage Modelling of Compressed Earth Blocks Stabilised with Cement
Advances in Civil Engineering, 2022 This work aims at studying the mechanical behaviour of compressed Earth blocks (CEBs) and compressed stabilised Earth blocks (CSEBs) with 4% and 8% in weight cement stabilisation.
Janvier Goutsaya +2 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
From dry yarns to complex 3D woven fabrics: a unified simulation methodology for deformation mechanics of textiles in tension, shear and draping [PDF]
, 2015 Common methods of modelling the behaviour of fibrous materials, such as yarns and (woven) fabrics, is to treat them as continuous solids. The fibrous behaviour is then taken into account by appropriate constitutive laws.
Daelemans, Lode, Van Paepegem, Wim
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Mechanics of materials model [PDF]
The Mechanics of Materials Model (MOMM) is a three-dimensional inelastic structural analysis code for use as an early design stage tool for hot section components.
Meister, Jeffrey P.
core +1 more source