Results 11 to 20 of about 10,501,738 (419)

Mechanics in biology [PDF]

open access: yesEurophysics News, 2020
Mechanics plays a key role in life, from simple tasks like providing protective shielding to highly complex ones such as cell division. To understand mechanical properties on the organism level, we need to zoom in to its constituent cells, then zoom back out to see how they collectively build tissues.
openaire   +4 more sources

Transcriptional analysis and target genes discovery of Pseudomonas aeruginosa biofilm developed ex vivo chronic wound model

open access: yesAMB Express, 2021
Bacterial biofilms formation is one of the major reasons for treatment failure in chronic wound infections. Therefore, diagnostic biomarkers remain the best option for prevention and treatment of chronic wound infections by biofilms.
Xiaojuan Tan   +6 more
doaj   +1 more source

In-organoid single-cell CRISPR screening reveals determinants of hepatocyte differentiation and maturation

open access: yesGenome Biology, 2023
Background Harnessing hepatocytes for basic research and regenerative medicine demands a complete understanding of the genetic determinants underlying hepatocyte differentiation and maturation.
Junbo Liang   +11 more
doaj   +1 more source

Mechanics rules cell biology [PDF]

open access: yesBMC Sports Science, Medicine and Rehabilitation, 2010
Cells in the musculoskeletal system are subjected to various mechanical forces in vivo. Years of research have shown that these mechanical forces, including tension and compression, greatly influence various cellular functions such as gene expression, cell proliferation and differentiation, and secretion of matrix proteins.
Bin Li, James H.-C. Wang
openaire   +4 more sources

Proteomic and functional profiling of platelet-derived extracellular vesicles released under physiological or tumor-associated conditions

open access: yesCell Death Discovery, 2022
During hemostasis, thrombosis, and inflammation, activated blood platelets release extracellular vesicles (PEVs) that represent biological mediators of physiological and pathological processes.
Mauro Vismara   +8 more
doaj   +1 more source

Alkaline phosphatase LapA regulates quorum sensing–mediated virulence and biofilm formation in Pseudomonas aeruginosa PAO1 under phosphate depletion stress

open access: yesMicrobiology Spectrum, 2023
Among various environmental stresses, the depletion of inorganic phosphate, which is an important signaling molecule that modulates virulence production, is notable. In our previous study, we demonstrated that lapA, encoding alkaline phosphatase, plays a
Xiaojuan Tan   +8 more
doaj   +1 more source

Studies on the cold tolerance of ratoon ‘Chaling’ common wild rice

open access: yesBiological Research, 2020
Background Rice is the staple food of many people around the world. However, most rice varieties, especially widely grown indica varieties and hybrids, are sensitive to cold stress.
Mengliang Xu   +5 more
doaj   +1 more source

Systems biology and mechanics of growth [PDF]

open access: yesWIREs Systems Biology and Medicine, 2015
In contrast to inert systems, living biological systems have the advantage to adapt to their environment through growth and evolution. This transfiguration is evident during embryonic development, when the predisposed need to grow allows form to follow function.
Eskandari, Mona, Kuhl, Ellen
openaire   +4 more sources

Towards molecular systems biology of gene transcription and regulation [PDF]

open access: yes, 2010
Ten years after the determination of the RNA polymerase 11 structure, the basic mechanism of mRNA synthesis during gene transcription is known. In the future, the initiation and regulation of transcription must be studied with a combination of structural
Cramer, Patrick
core   +1 more source

SARS-CoV-2: Structure, Biology, and Structure-Based Therapeutics Development

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
The pandemic of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been posing great threats to the world in many aspects. Effective therapeutic and preventive approaches including drugs and vaccines are still unavailable although
Mei-Yue Wang   +5 more
semanticscholar   +1 more source

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