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Mechanism and Finality in Biology
Azafea: Revista de Filosofía, 2011 This article defends a teleological approach which is compatible with our scientific image. It is held that organisms can be depicted as autonomous systems in which occurs autorregulation processes and exhibits a teleological behaviour oriented to an ...
Andrés Luis JAUME RODRÍGUEZ
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Europhysics News, 2020 Mechanics plays a key role in life, from simple tasks like providing protective shielding to highly complex ones such as cell division. To understand mechanical properties on the organism level, we need to zoom in to its constituent cells, then zoom back out to see how they collectively build tissues.
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Systems biology and mechanics of growth [PDF]
WIREs Systems Biology and Medicine, 2015 In contrast to inert systems, living biological systems have the advantage to adapt to their environment through growth and evolution. This transfiguration is evident during embryonic development, when the predisposed need to grow allows form to follow function.
Eskandari, Mona, Kuhl, Ellen
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Ferroptosis: mechanisms, biology and role in disease
Nature Reviews Molecular Cell Biology, 2021 The research field of ferroptosis has seen exponential growth over the past few years, since the term was coined in 2012. This unique modality of cell death, driven by iron-dependent phospholipid peroxidation, is regulated by multiple cellular metabolic pathways, including redox homeostasis, iron handling, mitochondrial activity and metabolism of amino
Xuejun Jiang +2 more
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Mechanics rules cell biology [PDF]
BMC Sports Science, Medicine and Rehabilitation, 2010 Cells in the musculoskeletal system are subjected to various mechanical forces in vivo. Years of research have shown that these mechanical forces, including tension and compression, greatly influence various cellular functions such as gene expression, cell proliferation and differentiation, and secretion of matrix proteins.
Wang James HC, Li Bin
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The concept of mechanism in biology [PDF]
Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences, 2012 The concept of mechanism in biology has three distinct meanings. It may refer to a philosophical thesis about the nature of life and biology ('mechanicism'), to the internal workings of a machine-like structure ('machine mechanism'), or to the causal explanation of a particular phenomenon ('causal mechanism').
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Mechanisms in molecular biology [PDF]
, 2017 The new mechanistic philosophy is divided into two largely disconnected projects. One deals with a metaphysical inquiry into how mechanisms relate to issues such as causation, capacities and levels of organization, while the other deals with epistemic issues related to the discovery of mechanisms and the intelligibility of mechanistic representations ...
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Epigenetics: Biology's Quantum Mechanics [PDF]
Frontiers in Plant Science, 2011 The perspective presented here is that modern genetics is at a similar stage of development as were early formulations of quantum mechanics theory in the 1920s and that in 2010 we are at the dawn of a new revolution in genetics that promises to enrich and deepen our understanding of the gene and the genome. The interrelationships and interdependence of
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Toward Mechanical Systems Biology in Bone [PDF]
Annals of Biomedical Engineering, 2012 ISSN:1573 ...
Trüssel, Andreas +2 more
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Molecular mechanisms of telomere biology disorders [PDF]
Journal of Biological Chemistry, 2021 Genetic mutations that affect telomerase function or telomere maintenance result in a variety of diseases collectively called telomeropathies. This wide spectrum of disorders, which include dyskeratosis congenita, pulmonary fibrosis, and aplastic anemia, is characterized by severely short telomeres, often resulting in hematopoietic stem cell failure in
Sherilyn Grill, Jayakrishnan Nandakumar
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