Results 11 to 20 of about 2,474,961 (353)

The concept of mechanism in biology [PDF]

open access: yesStudies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences, 2012
The concept of mechanism in biology has three distinct meanings. It may refer to a philosophical thesis about the nature of life and biology ('mechanicism'), to the internal workings of a machine-like structure ('machine mechanism'), or to the causal explanation of a particular phenomenon ('causal mechanism').
Nicholson, Daniel J.
openaire   +5 more sources

Towards molecular systems biology of gene transcription and regulation [PDF]

open access: yes, 2010
Ten years after the determination of the RNA polymerase 11 structure, the basic mechanism of mRNA synthesis during gene transcription is known. In the future, the initiation and regulation of transcription must be studied with a combination of structural
Cramer, Patrick
core   +1 more source

Studies on the cold tolerance of ratoon ‘Chaling’ common wild rice

open access: yesBiological Research, 2020
Background Rice is the staple food of many people around the world. However, most rice varieties, especially widely grown indica varieties and hybrids, are sensitive to cold stress.
Mengliang Xu   +5 more
doaj   +1 more source

Alkaline phosphatase LapA regulates quorum sensing–mediated virulence and biofilm formation in Pseudomonas aeruginosa PAO1 under phosphate depletion stress

open access: yesMicrobiology Spectrum, 2023
Among various environmental stresses, the depletion of inorganic phosphate, which is an important signaling molecule that modulates virulence production, is notable. In our previous study, we demonstrated that lapA, encoding alkaline phosphatase, plays a
Xiaojuan Tan   +8 more
doaj   +1 more source

Homeostasis as the Mechanism of Evolution. [PDF]

open access: yes, 2015
Homeostasis is conventionally thought of merely as a synchronic (same time) servo-mechanism that maintains the status quo for organismal physiology. However, when seen from the perspective of developmental physiology, homeostasis is a robust, dynamic ...
Torday, John S
core   +2 more sources

Making serine integrases work for us [PDF]

open access: yes, 2017
DNA site-specific recombinases are enzymes (often associated with mobile DNA elements) that catalyse breaking and rejoining of DNA strands at specific points, thereby bringing about precise genetic rearrangements.
Stark, W. Marshall
core   +1 more source

Mechanical and Systems Biology of Cancer

open access: yesComputational and Structural Biotechnology Journal, 2018
18 pages, 3 ...
Fabian Spill, Chris Bakal, Michael Mak
openaire   +6 more sources

Epigenetics: Biology's Quantum Mechanics [PDF]

open access: yesFrontiers in Plant Science, 2011
The perspective presented here is that modern genetics is at a similar stage of development as were early formulations of quantum mechanics theory in the 1920s and that in 2010 we are at the dawn of a new revolution in genetics that promises to enrich and deepen our understanding of the gene and the genome. The interrelationships and interdependence of
openaire   +4 more sources

The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression. [PDF]

open access: yes, 2016
Molecular classification of cancers into subtypes has resulted in an advance in our understanding of tumour biology and treatment response across multiple tumour types. However, to date, cancer profiling has largely focused on protein-coding genes, which
Backofen, Rolf   +27 more
core   +1 more source

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