Results 11 to 20 of about 2,453,415 (302)
Untangling the Conceptual Isssues Raised in Reydon and Scholz’s Critique of Organizational Ecology and Darwinian Populations [PDF]
, 2014 Reydon and Scholz raise doubts about the Darwinian status of organizational ecology by arguing that Darwinian principles are not applicable to organizational populations.
Aldrich H. E. +31 more
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Mechanical and Systems Biology of Cancer
Computational and Structural Biotechnology Journal, 2018 18 pages, 3 ...
Fabian Spill, Chris Bakal, Michael Mak
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Highly Optimized Tolerance: Robustness and Power Laws in Complex Systems [PDF]
, 1998 We introduce highly optimized tolerance (HOT), a mechanism that connects evolving structure and power laws in interconnected systems. HOT systems arise, e.g., in biology and engineering, where design and evolution create complex systems sharing common ...
Carlson, J. M., Doyle, John
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Epigenetics: Biology's Quantum Mechanics [PDF]
Frontiers in Plant Science, 2011 The perspective presented here is that modern genetics is at a similar stage of development as were early formulations of quantum mechanics theory in the 1920s and that in 2010 we are at the dawn of a new revolution in genetics that promises to enrich and deepen our understanding of the gene and the genome. The interrelationships and interdependence of
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Molecular mechanisms of telomere biology disorders [PDF]
Journal of Biological Chemistry, 2021 Genetic mutations that affect telomerase function or telomere maintenance result in a variety of diseases collectively called telomeropathies. This wide spectrum of disorders, which include dyskeratosis congenita, pulmonary fibrosis, and aplastic anemia, is characterized by severely short telomeres, often resulting in hematopoietic stem cell failure in
Sherilyn Grill, Jayakrishnan Nandakumar
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Genetically encoded fluorescent redox probes. [PDF]
, 2013 Redox processes are involved in almost every cell of the body as a consequence of aerobic life. In the past decades, redox biology has been increasingly recognized as one of the key themes in cell signaling.
Ai, Hui-Wang, Ren, Wei
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Collective oscillation period of inter-coupled biological negative cyclic feedback oscillators [PDF]
, 2014 A number of biological rhythms originate from networks comprised of multiple cellular oscillators. But analytical results are still lacking on the collective oscillation period of inter-coupled gene regulatory oscillators, which, as has been reported ...
Doyle III, Francis J. +3 more
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Is synthetic biology mechanical biology?
History and Philosophy of the Life Sciences, 2015 A widespread and influential characterization of synthetic biology emphasizes that synthetic biology is the application of engineering principles to living systems. Furthermore, there is a strong tendency to express the engineering approach to organisms in terms of what seems to be an ontological claim: organisms are machines.
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Ferroptosis: mechanisms, biology and role in disease
Nature Reviews Molecular Cell Biology, 2021 The research field of ferroptosis has seen exponential growth over the past few years, since the term was coined in 2012. This unique modality of cell death, driven by iron-dependent phospholipid peroxidation, is regulated by multiple cellular metabolic pathways, including redox homeostasis, iron handling, mitochondrial activity and metabolism of amino
Xuejun Jiang +2 more
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Buckling of a growing tissue and the emergence of two-dimensional patterns [PDF]
, 2013 The process of biological growth and the associated generation of residual stress has previously been considered as a driving mechanism for tissue buckling and pattern selection in numerous areas of biology.
Jensen, OE, King, JR, Nelson, MR
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