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Mechanisms in molecular biology [PDF]
, 2017 The new mechanistic philosophy is divided into two largely disconnected projects. One deals with a metaphysical inquiry into how mechanisms relate to issues such as causation, capacities and levels of organization, while the other deals with epistemic issues related to the discovery of mechanisms and the intelligibility of mechanistic representations ...
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Chiral separation in microflows [PDF]
, 2005 Molecules that only differ by their chirality, so called enantiomers, often possess different properties with respect to their biological function. Therefore, the separation of enantiomers presents a prominent challenge in molecular biology and belongs ...
A. J. Lichtenberg +8 more
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Collective oscillation period of inter-coupled biological negative cyclic feedback oscillators [PDF]
, 2014 A number of biological rhythms originate from networks comprised of multiple cellular oscillators. But analytical results are still lacking on the collective oscillation period of inter-coupled gene regulatory oscillators, which, as has been reported ...
Doyle III, Francis J. +3 more
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Molecular mechanisms of telomere biology disorders [PDF]
Journal of Biological Chemistry, 2021 Genetic mutations that affect telomerase function or telomere maintenance result in a variety of diseases collectively called telomeropathies. This wide spectrum of disorders, which include dyskeratosis congenita, pulmonary fibrosis, and aplastic anemia, is characterized by severely short telomeres, often resulting in hematopoietic stem cell failure in
Sherilyn Grill, Jayakrishnan Nandakumar
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Genetically encoded fluorescent redox probes. [PDF]
, 2013 Redox processes are involved in almost every cell of the body as a consequence of aerobic life. In the past decades, redox biology has been increasingly recognized as one of the key themes in cell signaling.
Ai, Hui-Wang, Ren, Wei
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Highly Optimized Tolerance: Robustness and Power Laws in Complex Systems [PDF]
, 1998 We introduce highly optimized tolerance (HOT), a mechanism that connects evolving structure and power laws in interconnected systems. HOT systems arise, e.g., in biology and engineering, where design and evolution create complex systems sharing common ...
Carlson, J. M., Doyle, John
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Untangling the Conceptual Isssues Raised in Reydon and Scholz’s Critique of Organizational Ecology and Darwinian Populations [PDF]
, 2014 Reydon and Scholz raise doubts about the Darwinian status of organizational ecology by arguing that Darwinian principles are not applicable to organizational populations.
Aldrich H. E. +31 more
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Biophysical Journal, 1962 I should like to begin by saying that I feel very diffident about speaking on the subject which the organizers of this Conference invited me to discuss with you. What I have to say will inevitably be limited by the extreme superficiality of my acquaintance with modem biochemistry and biophysics.
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Buckling of a growing tissue and the emergence of two-dimensional patterns [PDF]
, 2013 The process of biological growth and the associated generation of residual stress has previously been considered as a driving mechanism for tissue buckling and pattern selection in numerous areas of biology.
Jensen, OE, King, JR, Nelson, MR
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RNA Interference: Biology, Mechanism, and Applications [PDF]
Microbiology and Molecular Biology Reviews, 2003 SUMMARY Double-stranded RNA-mediated interference (RNAi) is a simple and rapid method of silencing gene expression in a range of organisms. The silencing of a gene is a consequence of degradation of RNA into short RNAs that activate ribonucleases to target homologous mRNA.
Neema, Agrawal +5 more
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