Results 61 to 70 of about 5,467,308 (207)

An Ultra‐Fast Rolling Double‐Helical Robot Driven by Constant Humidity

Advanced Science
Untethered soft robots made of stimuli‐responsive materials hold great application potential in various fields. However, most robots of this type require artificial modulation of the stimuli to actuate, while it is a great challenge to achieve fast ...
Chuhan Xu, Jiayao Ma, Lei Fu, Xinmeng Liu, Lei Zhang, Yan Chen   +5 more
doaj   +1 more source

The archaeo-eukaryotic GINS proteins and the archaeal primase catalytic subunit PriS share a common domain [PDF]

, 2010
This work was funded by the Scottish Universities Life Sciences Alliance (SULSA).Primase and GINS are essential factors for chromosomal DNA replication in eukaryotic and archaeal cells.
Agnieszka Swiatek, Swiatek Agnieszka, MacNeill, Stuart Andrew, MacNeill Stuart A, Stuart A MacNeill, Swiatek, Agnieszka   +5 more
core   +1 more source

Varieties of Noise: Analogical Reasoning in Synthetic Biology [PDF]

, 2013
The picture of synthetic biology as a kind of engineering science has largely created the public understanding of this novel field, covering both its promises and risks.
Knuuttila, Tarja, Loettgers, Andrea
core  

Theoretical basis of the community effect in development [PDF]

, 2011
Peer ...
Lhoussaine, Cédric, Thiel, Marco, Celine Kuttler, Saka, Yasushi, Kuttler, Celine, Marco Thiel, Cédric Lhoussaine, Yasushi Saka, Ullner, Ekkehard, Ekkehard Ullner   +9 more
core   +1 more source

Integrative analysis of single-cell and bulk transcriptome data reveals age-related immune cell alterations in primary glioblastoma associated with prognosis

Cancer Immunology, Immunotherapy
Background Glioblastoma (GBM) is the most malignant and highly recurrent brain tumor. Although over half of the GBM patients are elderly patients, the understanding of how aging affects GBM progression remains limited.
Zefan Jing, Bojun Qiu, Chenyang Ai, Chunhui Wang, Xinrun Wang, Boyang Li, Lin Hou, Bin Yin, Wei Han, Xiaozhong Peng   +9 more
doaj   +1 more source

Application of different methods used to transfect small molecule NADPH into cells [PDF]

Jichu yixue yu linchuang
Objective To compare the three different methods for direct transfection of small exogenous nicotinamide adenine dinucleotide phosphate(NADPH) into cells by a non-metabolic pathway.
LI Haoyue, DU Wenjing, LI Wei
doaj   +1 more source

Design of a crab-like bistable mechanism for nearly equal switching forces in forward and backward directions

, 2018
A compliant bistable mechanism with a crab-like structure for nearly equal switching forces in the forward and backward directions is developed. It consists of four crab-leg-like beams and a shuttle mass.
Dung-An Wang, 王東安, Ngoc Dang Khoa Tran   +2 more
core   +1 more source

ACAD8 deficiency promotes pathological cardiac hypertrophy in response to pressure overload by regulating histone isobutyrylation

Nature Communications
Branched-chain amino acids play critical roles in cardiac physiology and diseases. Genetic deficiency in the valine catabolic enzyme ACAD8 is clinically associated with isobutyryl-CoA deregulation and cardiomyopathy in humans, but its roles in cardiac ...
Jing-Yi Wang, Xin-Yan Zhao, Xin Sun, Yu-Fei Zhang, Li-Hong Sun, Xiang Wei, Ding-Sheng Jiang, Hui-Yu Wang, He-Ping Wang, Ke-Xin Si, Xiaoqiang Tang, Hou-Zao Chen, De-Pei Liu   +12 more
doaj   +1 more source

Enhanced B cell electroporation efficiency via inhibition of DNA-induced apoptosis and pyroptosis with pan-caspase inhibitor

Molecular Therapy: Methods & Clinical Development
B cells have immense potential as gene therapy carriers because of their ability to secrete therapeutic proteins and mediate immunological memory and tolerogenic functions. However, efficient gene delivery into primary B cells remains a challenge, as DNA
Gui-Lin Yang, Deng-Gao Wang, Xiang Zhao, De-Long Hao, Zhu-Qin Zhang, De-Pei Liu   +5 more
doaj   +1 more source

Cas6 specificity and CRISPR RNA loading in a complex CRISPR-Cas system [PDF]

, 2014
This research was funded in part by Biotechnology and Biological Sciences Research Council [BB/K000314/1]. The APC was paid through RCUK OA block grant funds.CRISPR-Cas is an adaptive prokaryotic immune system, providing protection against viruses and ...
Malcolm F. White, White, Malcolm F, Shirley Graham, Sokolowski, Richard David, Graham, Shirley, Richard D. Sokolowski   +5 more
core   +1 more source