Results 81 to 90 of about 5,467,308 (207)

Quantitative comparison of catalytic mechanisms and overall reactions in convergently evolved enzymes : implications for classification of enzyme function [PDF]

, 2010
The authors thank the National Institutes of Health (NIH R01 GM60595 to PCB) and the Scottish Universities Life Sciences Alliance (SULSA to JBOM) for funding.Functionally analogous enzymes are those that catalyze similar reactions on similar substrates ...
Almonacid, Daniel E, Daniel E Almonacid, Yera, Emmanuel R., Yera, Emmanuel R, Babbitt, Patricia C., Babbitt, Patricia C, John B O Mitchell, Almonacid Daniel E., Almonacid, Daniel E., Patricia C Babbitt, Yera Emmanuel R., Mitchell, John BO, Mitchell John B. O., Babbitt Patricia C., Emmanuel R Yera, Mitchell, John B. O.   +15 more
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Posttranscriptional Control of Neural Progenitors Temporal Dynamics During Neocortical Development by Syncrip

Advanced Science
The development of the mammalian neocortex is precisely regulated by temporal gene expression, yet the temporal regulatory mechanisms of cortical neurogenesis, particularly how radial glial cells (RGCs) sequentially generate deep to superficial neurons ...
Jiarui Wu, Haoyang Yu, Xinyi Dou, Bin Yin, Lin Hou, Yuanchao Xue, Boqin Qiang, Pengcheng Shu, Xiaozhong Peng   +8 more
doaj   +1 more source

Effects of intraperitoneal injection of busulfan on metabolic characteristics of spermatogonial stem cells [PDF]

Jichu yixue yu linchuang
Objective To establish a mouse model treated with busulfan and to investigate its effects on the metabolism of spermatogonial stem cells (SSCs) of mouse testis.
YU Zhixin, MANG Xinyu, ZOU Dingfeng, MIAO Shiying, SONG Wei, LI Kai
doaj   +1 more source

Be aware of behaviour: learning and teaching behavioural biology in secondary education [PDF]

, 2012
Learning and teaching New Biology requires new educational approaches to acquire knowledge of the (new) biology, competences to understand complex systems, and new learning and teaching strategies.
van Moolenbroek, J., Biology Education, Sub Onderwijsinstituut Biologie   +2 more
core   +1 more source

Experimental Biology & Communication

, 2023
This introductory biology laboratory course covers the application of experimental techniques in microbiology, biochemistry, cell and developmental biology.
Steiner, Lisa, Guarente, Leonard, RajBhandary, Uttam, King, Jonathan   +3 more
core   +1 more source

Atypical β-strand insertion mediates the noncovalent cross-linking in amyloid aggregates

Nature Communications
β-Strand motifs are essential recognition modules in protein-protein interactions (PPIs), which govern cellular signaling networks and regulate molecular pathway dynamics. Herein we present an unexpected discovery of a previously uncharacterized β-strand
Shanshan Mo, Ruonan Wang, Zhongyi Jian, Mingwei Liu, Feiyi Zhang, Zhun Deng, Wenbo Zhang, Yanlian Yang, Chen Wang, Lanlan Yu, Mingzhan Wang, Chenxuan Wang   +11 more
doaj   +1 more source

Synthetic Biology: Advancing Biological Frontiers by Building Synthetic Systems [PDF]

, 2012
Advances in synthetic biology are contributing to diverse research areas, from basic biology to biomanufacturing and disease therapy. We discuss the theoretical foundation, applications, and potential of this emerging field.Version of ...
Yvonne Y Chen, Chen, Yvonne Y., Smolke, Christina D, Smolke, Christina D., Chen, Yvonne Yu-Hsuan, Kate E Galloway, Christina D Smolke, Galloway, Kate E., Chen, Yvonne Y, Galloway, Kate E   +9 more
core   +1 more source

The Regulatory Role of microRNA in Neocortical Layer Formation

Shengwu huaxue yu shengwu wuli jinzhan
Laminar organization is a hallmark of the mammalian neocortex, where the orderly arrangement of diverse neurons stereotypically forms into six distinct layers.
SHU Peng-Cheng, DOU Xin-Yi
doaj   +1 more source

The transmembrane channel-like 6 (TMC6) in primary sensory neurons involving thermal sensation via modulating M channels

Frontiers in Pharmacology
Introduction: The transmembrane channel-like (TMC) protein family contains eight members, TMC1–TMC8. Among these members, only TMC1 and TMC2 have been intensively studied. They are expressed in cochlear hair cells and are crucial for auditory sensations.
Yating An, Jingyi Hu, Han Hao, Weixin Zhao, Xiaoxue Zhang, Jicheng Shao, Caixue Wang, Xinmeng Li, Chao Liu, Jinsha He, Yiwen Zhao, Hailin Zhang, Xiaona Du   +12 more
doaj   +1 more source

Implications of Big Data for cell biology

, 2015
“Big Data” has surpassed “systems biology” and “omics” as the hottest buzzword in the biological sciences, but is there any substance behind the hype? Certainly, we have learned about various aspects of cell and molecular biology from the many individual
Dolinski, Kara, Troyanskaya, Olga
core   +1 more source