Results 81 to 90 of about 2,563,843 (205)

Design and construction of a new Drosophila species, D.synthetica, by synthetic regulatory evolution [PDF]

open access: yes, 2011
Here, I merge the principles of synthetic biology^1,2^ and regulatory evolution^3-11^ to create a new species^12-15^ with a minimal set of known elements.
Eduardo Moreno
core   +1 more source

Copine-6 is a TRPM3 escort protein controlling the sensitivity of sensory neurons to noxious heat

open access: yesThe EMBO Journal
Copine-6 is a calcium-sensitive phospholipid-binding protein of the evolutionarily conserved Copine family. In the central nervous system, Copine-6 regulates function of some neurotransmitter receptors and structural plasticity of dendritic spines ...
Yiting Gao   +9 more
doaj   +1 more source

Genetic deletion of zinc transporter ZnT3 induces progressive cognitive deficits in mice by impairing dendritic spine plasticity and glucose metabolism

open access: yesFrontiers in Molecular Neuroscience
Zinc transporter 3 (ZnT3) is abundantly expressed in the brain, residing in synaptic vesicles, where it plays important roles in controlling the luminal zinc levels.
Rui Zong   +10 more
doaj   +1 more source

Development of a Low-Cost Platform for 3D Bioprinting Applications [PDF]

open access: yes, 2017
Due to the fast pace advancements in 3D printing technologies, it is now possible to bring to life three-dimensional models designed on a computer. The growing availability of user-friendly, high-resolution printers, presents us with the opportunity to ...
Emanuel, Anthony, Ontiveros, Fernando
core   +1 more source

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

open access: yesAdvanced Science
Damage to the cochlear outer hair cell (OHC) is a major cause of deafness in mammals. OHCs amplify the auditory signals to enhance the sensitivity and sound frequency selectivity of the auditory system.
Shengnan Wang   +15 more
doaj   +1 more source

Global comprehensive transcriptomic and proteomic analyses of murine terminal erythroid differentiation

open access: yesGlobal Medical Genetics
Background: Terminal erythroid differentiation (TED) is the maturation process of proerythroblasts into enucleated erythrocytes. Animal models are essential for studying red blood cell disorders. Methods: We isolated erythroblasts at different TED stages
Xiao-Yue Tang   +14 more
doaj   +1 more source

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