Results 111 to 120 of about 4,146,035 (404)
The effective action and the triple Pomeron vertex [PDF]
We study integrations over light-cone momenta in the gauge invariant effective action of high energy QCD. A regularization mechanism which allows for the evaluation of the longitudinal integrations is presented.
Bartels+6 more
core +1 more source
The review presents data on the role of succinates in critically ill patients with hypoxia, the mechanisms of action of succinates at the cellular level, and their place in the treatment regimens.
Yu. P. Orlov
doaj +1 more source
Mechanism of Action of Anti-TNF Therapy in Inflammatory Bowel Disease.
Several anti-tumour necrosis factor [TNF] blocking strategies have been evaluated in patients with Crohn's disease. Compounds that have been tested included the full monoclonal IgG1 antibodies infliximab and adalimumab, the pegylated anti-TNF F[ab']2 ...
A. Levin+2 more
semanticscholar +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
N=4 Super Yang-Mills Low-Energy Effective Action at Three and Four Loops
We investigate the low-energy effective action in N=4 super Yang-Mills theory with gauge group SU(n) spontaneously broken down to its maximal torus. Using harmonic superspace technique we prove an absence of any three- and four-loop corrections to non ...
Buchbinder, I. L., Petrov, A. Yu.
core +1 more source
Mechanism of action of antidepressants.
A wide range of effective drugs is available for the treatment of major depression. The discovery of these agents has not always been the result of rational drug design. Tricyclic antidepressants formed the mainstay of treatment until the 1990s, and selective serotonin reuptake inhibitors (SSRIs) have dominated treatment over the last decade.
Artigas, Francesc+2 more
openaire +2 more sources
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
Genomic and non-genomic actions of glucocorticoids in asthma
Glucocorticoids are the mainstay of asthma therapy. They are primarily used to suppress airway inflammation, which is the central pathological change in asthmatic patients′ airways. This is achieved by many different mechanisms.
Alangari Abdullah
doaj
Anti-tumor necrosis factor (TNF) antibodies are successfully used in the therapy of inflammatory bowel diseases (IBD). However, the molecular mechanism of action of these agents is still a matter of debate.
U. Billmeier+3 more
semanticscholar +1 more source
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source