Results 101 to 110 of about 3,969,170 (352)
The Higgs mechanism from the effective theory of the non-minimal gravity action [PDF]
, 2021 Suppanat Supanyo +3 more
openalex +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Review of the Mechanisms of Caffeine Effect on Skin and Hair Health
مجله دانشکده پزشکی اصفهان, 2016 Caffeine -a methylxanthine derived from purine- is found in the various plants (coffee, tea, cola) all over the world and is widely used in cosmetics due to its ability to penetrate in skin barriers.
Hanieh Sharifian-Koupaiee +3 more
doaj
Drug Design, Development and Therapy, 2023 Sihua Wen,1,* Kai Yang,1,* Yunfeng Bai,2 Yanan Wu,1 Ding Liu,1 Xu Wu,1 Xiaofei Zhang,1 Jing Sun1 1Department of Pharmaceutics, The Key Laboratory of Basic and New Drug Research of Traditional Chinese Medicine, Shaanxi University of Chinese ...
Wen S +7 more
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Biologically Active Nonribosomal Peptides.I. Nonribosamal Polypeptide Antibiotics
Антибиотики и Химиотерапия, 2020 The data on novel polypeptide antibiotics described within the last 10-15 years, as well as new researches on the known antibiotics with respect to their mechanisms of action and microbial resistance are presented.
T. I. Orlova +2 more
doaj
Mechanism of action of somatostatin: Inhibition of ionophore A23187‐induced release of growth hormone from dispersed bovine pituitary cells [PDF]
, 1976 R.J. Bicknell, Joe Schofield
openalex +1 more source
Theory of deferred action: Agent-based simulation model for designing complex adaptive systems [PDF]
, 2009 Deferred action is the axiom that agents act in emergent organisation to achieve predetermined goals. Enabling deferred action in designed artificial complex adaptive systems like business organisations and IS is problematical.
Eldabi, T, Khan, T, Patel, NV
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