Results 101 to 110 of about 175,059,218 (262)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Photographs separated from various series in the Action for Soviet Jewry records (8 digital images)
Photographs separated from the Series I-X of the Action for Soviet Jewry records. Photographs of Sakharov Tribute speakers Harrison Salisbury, Fishbach, Gershman (separated from Box 112, Folder 8).Digital ImageDigital finding ...
Action for Soviet Jewry
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This collection includes reports, ephemera, images, publications and working papers, which form part of the Caribbean Association of Feminist Research Action (CAFRA ...
Caribbean Association for Feminist Research & Action (CAFRA)
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Action research on action research: A facilitator’s account
This article describes research conducted by a facilitator of a statewide action research network, the Wyoming Teacher Policy Institute (WTPI).
Trent, Allen
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Photographs separated from various series in the Action for Soviet Jewry records (4 digital images)
Photographs separated from the Series I-X of the Action for Soviet Jewry records. Photographs of Yaakov Khantsis in Boston (separated from Box 3, Folder 4).Digital ImageDigital finding ...
Action for Soviet Jewry
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Photographs separated from various series in the Action for Soviet Jewry records (34 digital images)
Photographs separated from the Series I-X of the Action for Soviet Jewry records. Photographs from the trip by Stephen Freidberg.
Action for Soviet Jewry
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source

