Results 301 to 310 of about 3,910,323 (355)
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Mechanisms of antihormone action
The Journal of Steroid Biochemistry and Molecular Biology, 1992The mechanisms of action of two types of anti-hormones is discussed. Type I anti-hormones comprise the antiestrogen hydroxy-tamoxifen and the antiprogestin RU486, both of which promote DNA binding of the cognate receptors and, due to the activity of one of the two transcription activation functions of the estrogen and progesterone receptors, act as ...
Gronemeyer, H. +11 more
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Allergy, 2003
Intravenous immunoglobulin (IVIG) preparations are fractionated from a plasma pool of several thousand donors. IVIG contain immune antibodies and physiologic autoantibodies. Immune antibodies reflect the immunologic experience of the donor population. This fraction of IVIG preparations is useful for replacement therapy and passive immunisation. Natural
H U, Simon, P J, Späth
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Intravenous immunoglobulin (IVIG) preparations are fractionated from a plasma pool of several thousand donors. IVIG contain immune antibodies and physiologic autoantibodies. Immune antibodies reflect the immunologic experience of the donor population. This fraction of IVIG preparations is useful for replacement therapy and passive immunisation. Natural
H U, Simon, P J, Späth
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New England Journal of Medicine, 1973
LITHIUM first attracted medical attention in the 19th century when A. B. Garrod attempted to treat gout with Li+ because Li+ urate was found to be more soluble than Na+ or K+ urate.
I, Singer, D, Rotenberg
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LITHIUM first attracted medical attention in the 19th century when A. B. Garrod attempted to treat gout with Li+ because Li+ urate was found to be more soluble than Na+ or K+ urate.
I, Singer, D, Rotenberg
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Mechanisms of Interferon Action
1998The interferons (IFNs) are a family of cytokines that elicit pleiotropic biological effects (Pestka et al. 1987; DeMaeyer and DeMaeyer-Guignard 1988; Sen and Lengyel 1992). Although best known (and named) for their ability to inhibit viral replication in treated cells, IFNs are also capable of regulating cellular proliferation, differentiation, and ...
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Thrombosis Research, 1983
Aspirin, one of the oldest antiplatelet agents used for antithrombotic therapy, has been demonstrated to cause acetylation of the cyclo-oxygenase and irreversible inhibition of thromboxane synthesis for the life of the platelet. Aspirin has a similar effect upon the endothelial cyclo-oxygenase, but in contrast to that of the platelet, it is less ...
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Aspirin, one of the oldest antiplatelet agents used for antithrombotic therapy, has been demonstrated to cause acetylation of the cyclo-oxygenase and irreversible inhibition of thromboxane synthesis for the life of the platelet. Aspirin has a similar effect upon the endothelial cyclo-oxygenase, but in contrast to that of the platelet, it is less ...
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Probiotic mechanisms of action
Early Human Development, 2019Intestinal dysbiosis is associated with a large number of disease processes including necrotizing enterocolitis and late-onset sepsis in preterm infants and colic and antibiotic-associated diarrhea in term infants. Probiotic microbes are increasingly administered to infants with the intent of decreasing risk of these acute diseases as well as chronic ...
Katrina, Halloran, Mark A, Underwood
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Physiological Reviews, 2001
Our appreciation of the physiological functions of estrogens and the mechanisms through which estrogens bring about these functions has changed during the past decade. Just as transgenic mice were produced in which estrogen receptors had been inactivated and we thought that we were about to understand the role of estrogen receptors in physiology and ...
S, Nilsson +9 more
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Our appreciation of the physiological functions of estrogens and the mechanisms through which estrogens bring about these functions has changed during the past decade. Just as transgenic mice were produced in which estrogen receptors had been inactivated and we thought that we were about to understand the role of estrogen receptors in physiology and ...
S, Nilsson +9 more
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Mechanisms of Anthelmintic Action
1975In the vast field of medical sciences, parasitology constitutes a small segment and has received comparatively scant attention, though worm infestation is a medical and public health problem of great magnitude, both in man and domesticated animals. The economic loss in terms of morbidity in man, loss of man-hours of work, and poor quality of animals ...
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Biochimica et Biophysica Acta (BBA) - Enzymology, 1979
Uricase (urate:oxygen oxidoreductase, EC 1.7.3.3) exposes a positional and steric specificity in the enzymic conversion of urate to allantoin. C-2 of urate was recovered as C-2 of allantoin. By the consecutive oxidation and hydrolysis reactions a levorotatory intermediate was formed, presumably (-)-2-oxo-4-hydroxy-4-carbohydroxy-5-ureido-imidazoline ...
G P, Bongaerts, G D, Vogels
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Uricase (urate:oxygen oxidoreductase, EC 1.7.3.3) exposes a positional and steric specificity in the enzymic conversion of urate to allantoin. C-2 of urate was recovered as C-2 of allantoin. By the consecutive oxidation and hydrolysis reactions a levorotatory intermediate was formed, presumably (-)-2-oxo-4-hydroxy-4-carbohydroxy-5-ureido-imidazoline ...
G P, Bongaerts, G D, Vogels
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Oxcarbazepine: Mechanisms of Action
Epilepsia, 1994Summary: The antiepileptic drug (AED) oxcarbazepine (OCBZ) and its rapidly formed 10‐monohydroxy metabolite (MHD) protect against electroshock‐induced tonic hindlimb extension in rodents (ED50 14–21 mg/kg p.o.). Both stereoisomers of MHD also protect.
M J, McLean +5 more
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