Results 31 to 40 of about 3,969,170 (352)
Open inflation from quantum cosmology with a strong nonminimal coupling [PDF]
, 1998 We propose the mechanism of quantum creation of the open Universe in the observable range of values of $\Omega$. This mechanism is based on the no-boundary quantum state with the Hawking-Turok instanton applied to the model with a strong nonminimal ...
A.O. Barvinsky +44 more
core +2 more sources
Analgesic choice in dentistry. Part I: The mechanism of action
Brazilian Journal of Oral Sciences, 2015 Analgesics are frequently used in dentistry for the management of dental pain. Dental clinicians should choose the medicine based on its mechanism of action and toxicity, to promote a successful analgesic effect as well as comfort to the patient.
Filipe Polese Branco +3 more
doaj +1 more source
The mechanisms of action of metformin [PDF]
Diabetologia, 2017 Metformin is a widely-used drug that results in clear benefits in relation to glucose metabolism and diabetes-related complications. The mechanisms underlying these benefits are complex and still not fully understood. Physiologically, metformin has been shown to reduce hepatic glucose production, yet not all of its effects can be explained by this ...
Rena, Graham +2 more
openaire +3 more sources
An Exploration of the Mechanism of Action of an Equine-Assisted Intervention
Animals, 2019 Though long alluded to, there is now an accumulation of evidence of the vital contribution that emotion makes to learning. Within this broad advance in understanding is a growing body of research emphasising the embodied nature of this emotion-based ...
Ann Hemingway +4 more
doaj +1 more source
Pharmaceutics, 2021 We describe the design and attributes of a linear pentapeptide-like derivative (C14(ω5)OOc10O) screened for its ability to elicit bactericidal competences of plasma constituents against Gram-negative bacteria (GNB).
Fadia Zaknoon, Ohad Meir, Amram Mor
doaj +1 more source
Structural basis of complement membrane attack complex formation [PDF]
, 2015 In response to complement activation, the membrane attack complex (MAC) assembles from fluid-phase proteins to form pores in lipid bilayers. MAC directly lyses pathogens by a ‘multi-hit’ mechanism; however, sublytic MAC pores on host cells activate ...
Bubeck, D +3 more
core +1 more source
BIOMOLECULAR MECHANISM OF ANTI EPILEPTIC DRUGS
Malang Neurology Journal, 2018 Epilepsy therapy is almost always chronic and often used more than one drug. Currently, antiepileptic drugs are still the mainstay of therapy for epilepsy. An understanding of the pharmacodynamics and pharmacokinetics of these drugs would be very helpful
Machlusil Husna +1 more
doaj +1 more source
The role of response mechanisms in determining reaction time performance: Piéron’s Law revisited [PDF]
, 2004 A response mechanism takes evaluations of the importance of potential actions and selects the most suitable. Response mechanism function is a nontrivial problem that has not received the attention it deserves within cognitive psychology. In this article,
Gurney, K.N., Stafford, T.
core +2 more sources
Alitretinoin in treatment of chronic hand eczema – mechanism of action
Przegląd Dermatologiczny, 2016 Hand eczema is a common skin disorder with significant functional and economic impacts. Conventional therapy options, such as topical corticosteroids, calcineurin inhibitors, phototherapy and systemic immunosuppressants, often give unsatisfactory results,
Maria Matejko, Beata Kręcisz
doaj +1 more source
Properties and synthesis of milrinone [PDF]
Hemijska Industrija, 2013 Milrinone, 1,6-dihydro-2-methyl-6-oxo-[3,4’-bipyridine]-5-carbonitrile, is a positive inotropic cardiotonic agent with vasodilator properties that acts as selective phosphodiesterase 3 inhibitor in cardiac and vascular smooth muscle.
Mirković Jelena M. +2 more
doaj +1 more source