Results 51 to 60 of about 175,059,218 (262)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Antibacterial activity and mechanism of action of a mammal proline-rich peptide

open access: yes, 2016
Antibacterial activity and mechanism of action of a mammal proline-rich ...
A Giovannelli   +7 more
core  

Researching resilience in action: Matters of action research as ‘matters of care’

open access: yes, 2022
This paper traces my Action Research (AR) journey and suggests a care perspective to AR. In my research that investigated the idea of resilience in disaster recovery, I engaged in a five-year collaborative inquiry of what it means to do resilience with a
Mikami, Akina
core  

Role of micronutrients and natural antioxidants in fighting against HIV; a quick mini-review [PDF]

open access: yesResearch Journal of Pharmacognosy, 2014
Oxidative stress has been implicated in the progression of HIV to AIDS, since HIV usually replicates in a highly oxidized condition and CD4+ T lymphocytes can be activated via a cascade of internal oxidative pathways, which enhances the formation of ...
S. Saeidnia, M. Abdollahi
doaj  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Mechanisms of Resistance to Chemotherapy in Hypopharyngeal Carcinoma

open access: yesBiomedicines
Hypopharyngeal carcinoma (HPC) represents the most prognostically unfavorable subtype among head and neck malignancies. Platinum-based neoadjuvant chemotherapy serves as a critical therapeutic approach for improving outcomes in hypopharyngeal carcinoma ...
Zhaoyue Lu   +3 more
doaj   +1 more source

Ketogenic Diet Mechanism of Action

open access: yesPediatric Neurology Briefs, 1996
The intracellular pH of the cerebral cortex was studied by the neutral red method in 15 adult rats maintained on ketogenic and control diets for 5-6 weeks.
J Gordon Millichap
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Genomic and non-genomic actions of glucocorticoids in asthma

open access: yesAnnals of Thoracic Medicine, 2010
Glucocorticoids are the mainstay of asthma therapy. They are primarily used to suppress airway inflammation, which is the central pathological change in asthmatic patients′ airways. This is achieved by many different mechanisms.
Alangari Abdullah
doaj  

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