Results 71 to 80 of about 3,969,170 (352)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Influence of Formulation, Buffering, pH and Divalent Cations on the Activity of Endothall on Hydrilla. [PDF]

open access: yes, 2003
Endothall has been used as an aquatic herbicide for more than 40 years and provides very effective weed control of many weeds. Early research regarding the mechanism-of-action of endothall contradicts the symptomology normally associated with the ...
Bewick, T. A.   +4 more
core  

Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates [PDF]

open access: yes, 2018
Nitrogen-containing-bisphosphonates (N-BPs) are widely prescribed to treat osteoporosis and other bone-related diseases. Although previous studies established that N-BPs function by inhibiting the mevalonate pathway in osteoclasts, the mechanism by which
Abu-Remaileh, Monther   +9 more
core   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Traditional Chinese Medicine for Breast Cancer: A Review

open access: yesBreast Cancer: Targets and Therapy, 2023
Rui-Qi Feng,1 De-Hui Li,2 Xu-Kuo Liu,1 Xiao-Hui Zhao,1 Qian-Er Wen,1 Ying Yang1 1Graduate School of Hebei University of Chinese Medicine, Shijiazhuang, Hebei Province, People’s Republic of China; 2Oncology Department II, the First Affiliated Hospital of ...
Feng RQ   +5 more
doaj  

An equivalence of two mass generation mechanisms for gauge fields

open access: yes, 2008
Two mass generation mechanisms for gauge theories are studied. It is proved that in the abelian case the topological mass generation mechanism introduced in hep-th/9301060, hep-th/9512216 is equivalent to the mass generation mechanism defined in hep-th ...
ALEXEY SEVOSTYANOV   +2 more
core   +1 more source

Coherent nonhelical shear dynamos driven by magnetic fluctuations at low Reynolds numbers [PDF]

open access: yes, 2015
Nonhelical shear dynamos are studied with a particular focus on the possibility of coherent dynamo action. The primary results -- serving as a follow up to the results of Squire & Bhattacharjee [arXiv:1506.04109 (2015)] -- pertain to the "magnetic shear ...
Bhattacharjee, Amitava, Squire, Jonathan
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Depression, an unmet health need in Africa: Understanding the promise of ketamine

open access: yesHeliyon
In Africa, there is currently a paucity of data on the epidemiology of depression, its treatment and management. The prevalence of depression is severely underestimated, with unique circumstances and societal risk factors associated with depression and ...
Aletta ME. Millen   +2 more
doaj   +1 more source

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