Results 41 to 50 of about 18,551 (276)
Squeezing the eggs to grow: The mechanobiology of mammalian folliculogenesis
Frontiers in Cell and Developmental Biology, 2022 The formation of functional eggs (oocyte) in ovarian follicles is arguably one of the most important events in early mammalian development since the oocytes provide the bulk genetic and cytoplasmic materials for successful reproduction.
Arikta Biswas +4 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira +8 more
wiley +1 more source
Mechanobiology of tooth movement [PDF]
The European Journal of Orthodontics, 2008 This review describes the mechanical and biological signalling pathways during orthodontic tooth movement and provides an update of the current literature. A theoretical model is introduced to elucidate the complex cascade of events after the application of an orthodontic force to a tooth.
Henneman, S. +2 more
openaire +3 more sources
Transient Cytoskeletal Anisotropy Encodes Short‐Term Mechanical Memory in Glioblastoma Cells
Advanced Materials, EarlyView.The same mechanical deformation can produce distinct cytoskeletal states depending on loading history. Experiments and constitutive modeling reveal that transient actin–vimentin anisotropy stores mechanical information and governs short‐term mechanical memory in glioblastoma cells.
Clara Gomez‐Cruz +5 more
wiley +1 more source
Single cell imaging-based chromatin biomarkers for tumor progression
Scientific Reports, 2021 Tumour progression within the tissue microenvironment is accompanied by complex biomechanical alterations of the extracellular environment. While histopathology images provide robust biochemical markers for tumor progression in clinical settings, a ...
Saradha Venkatachalapathy +3 more
doaj +1 more source
Advanced Materials, EarlyView.We present elastomeric three‐dimensional (3D) microstructures fabricated via two‐photon polymerization (2PP) and post‐processed through wet etching, for quantifying nanonewton (nN)‐scale forces applied by healthy and diseased neural cells. The mechanically characterized free‐standing beam architectures enable measurement of traction forces of ...
Pieter F. J. van Altena +7 more
wiley +1 more source
Surface mechanics and compressive stress impact mammalian follicle development
Nature CommunicationsThe maturation of functional eggs in ovaries is essential for successful reproduction in mammals. Despite its biological and clinical importance, the underlying mechanisms regulating folliculogenesis remain enigmatic.
Arikta Biswas +11 more
doaj +1 more source
Advanced Materials, EarlyView.Rapid thiol‐maleimide addition frequently outpaces mixing, resulting in heterogeneous hydrogels. S‐nitrosothiols act as thiol‐protecting groups, allowing uniform mixing with maleimide‐functionalized polymers before gelation. Sodium thiosulfate or sodium ascorbate then regenerates thiols on demand, triggering controlled thiol‐maleimide crosslinking ...
Julian A. Serna +7 more
wiley +1 more source
Nature CommunicationsChromatin-lamina interactions regulate gene activity by forming lamina-associated domains (LADs), which contribute to cellular identity through gene repression.
Monika Dhankhar +9 more
doaj +1 more source