Results 41 to 50 of about 35,268 (338)

Syncytial germline architecture is actively maintained by contraction of an internal actomyosin corset

open access: yesNature Communications, 2018
Germline cells in many species are fused to form a syncytium but the mechanics behind the maintenance of these structures are poorly defined. Here, the authors propose an inner contractile actomyosin corset provides a supportive framework to maintain ...
Agarwal Priti   +6 more
doaj   +1 more source

Mechanobiology of orthodontic tooth movement: An update.

open access: yesJournal of the World Federation of Orthodontists, 2023
The purpose of this review is to provide an update on the changes at the cellular and tissue level occurring during orthodontic force application. For the understanding of this process, knowledge of the mechanobiology of the periodontal ligament and the ...
J. Maltha, A. Kuijpers-Jagtman
semanticscholar   +1 more source

Persistent Vascular Collagen Accumulation Alters Hemodynamic Recovery from Chronic Hypoxia [PDF]

open access: yes, 2012
Pulmonary arterial hypertension (PAH) is caused by narrowing and stiffening of the pulmonary arteries that increase pulmonary vascular impedance (PVZ). In particular, small arteries narrow and large arteries stiffen. Large pulmonary artery (PA) stiffness
Chesler, Naomi C.   +5 more
core   +2 more sources

Mechanobiology

open access: yesInternational Journal For Multidisciplinary Research
Mechanobiology is an emerging field of multidisciplinary research studying how the physical properties of the cell environment and mechanical loads regulate biological processes at the cellular, tissue, and molecular levels. It adopts ideas from physics, biology, and engineering to comprehend how cells sense, translate, and respond to mechanical ...
Magham Ramachandra   +2 more
  +4 more sources

Optogenetic control of YAP can enhance the rate of wound healing

open access: yesCellular & Molecular Biology Letters, 2023
Background Tissues need to regenerate to restore function after injury. Yet, this regenerative capacity varies significantly between organs and between species.
Pearlyn Jia Ying Toh   +2 more
doaj   +1 more source

Elastomeric Pillar Cages Modulate Actomyosin Contractility of Epithelial Microtissues by Substrate Stiffness and Topography

open access: yesCells, 2023
Cell contractility regulates epithelial tissue geometry development and homeostasis. The underlying mechanobiological regulation circuits are poorly understood and experimentally challenging.
Lisann Esser   +8 more
doaj   +1 more source

Mechanobiology in the eye. [PDF]

open access: yesNPJ Biol Phys Mech
The eye presents a very dynamic biomechanical environment, and thus ocular cells must be highly mechanosensitive and mechanoresponsive. Moreover, defects in mechanobiological pathways contribute to a number of sight-threatening ocular diseases ...
Ethier CR, Herberg S.
europepmc   +2 more sources

A model for the anisotropic response of fibrous soft tissues using six discrete fibre bundles [PDF]

open access: yes, 2010
The development of accurate constitutive models of fibrous soft-tissues is a challenging problem. Many consider the tissue to be a collection of fibres with a continuous distribution function representing their orientations. A novel discrete fibre model
Flynn, C., Nielsen, P., Rubin, M. B.
core   +1 more source

Mechanobiology of the meniscus [PDF]

open access: yesJournal of Biomechanics, 2015
The meniscus plays a critical biomechanical role in the knee, providing load support, joint stability, and congruity. Importantly, growing evidence indicates that the mechanobiologic response of meniscal cells plays a critical role in the physiologic, pathologic, and repair responses of the meniscus.
McNulty, Amy L, Guilak, Farshid
openaire   +2 more sources

The intrinsic stiffness of human trabecular meshwork cells increases with senescence. [PDF]

open access: yes, 2015
Dysfunction of the human trabecular meshwork (HTM) plays a central role in the age-associated disease glaucoma, a leading cause of irreversible blindness.
Chang, Yow-Ren   +4 more
core   +3 more sources

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