Results 31 to 40 of about 18,551 (276)
Cells, 2023 Cell contractility regulates epithelial tissue geometry development and homeostasis. The underlying mechanobiological regulation circuits are poorly understood and experimentally challenging.
Lisann Esser +8 more
doaj +1 more source
Predictive Modeling in Musculoskeletal Mechanobiology
, 2016 This chapter provides an overview of the main concepts in mechanobiology and touches upon the experimental models that are most frequently used to study mechanobiology on a cell and tissue level.
Khayyeri, Hanifeh, +3 more
core +1 more source
, 2022 Leveraging the differential response of genes to mechanical loading may allow for the identification of novel therapeutics and we have recently established placental growth factor (PGF) as a mechanically augmented gene which promotes angiogenesis at ...
Eamon Sheehy (7895390) +7 more
core +3 more sources
Biology Open, 2013 Summary Because the actin network in active lamellipodia is continuously assembling at the edge, moving inward and disassembling, there is a question as to how actin-binding proteins and other components are transported to the leading edge and how ...
Prabuddha Gupta +10 more
doaj +1 more source
Active biomaterials for mechanobiology
Biomaterials, 2021 Active biomaterials offer novel approaches to study mechanotransduction in mammalian cells. These material systems probe cellular responses by dynamically modulating their resistance to endogenous forces or applying exogenous forces on cells in a temporally controlled manner.
Özkale B, Sakar MS, Mooney DJ
openaire +4 more sources
Orthopedic Mechanophenotype: A Structured Narrative Review of Multiscale Biomechanics, Mechanotransduction, and Clinical Decision-Making. [PDF]
Orthop SurgThe orthopedic mechanophenotype framework comprises load exposure, tissue susceptibility, and biological adaptability axes to decode mechanical‐biological crosstalk. It guides clinical phenotyping, targeted intervention, and response monitoring for orthopedic disorders beyond static morphological assessment.
Lan Z, Mu Z, Li H.
europepmc +2 more sources
International Journal For Multidisciplinary ResearchMechanobiology is an emerging field of multidisciplinary research studying how the physical properties of the cell environment and mechanical loads regulate biological processes at the cellular, tissue, and molecular levels. It adopts ideas from physics, biology, and engineering to comprehend how cells sense, translate, and respond to mechanical ...
Magham Ramachandra +2 more
+4 more sources
Non-canonical activation of OmpR drives acid and osmotic stress responses in single bacterial cells
Nature Communications, 2017 OmpR is a transcription factor activated in acid and osmotic responses of Gram-negative bacteria, leading to acidification of the bacterial cytoplasm.
Smarajit Chakraborty +4 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Platelet function tests are essential to profile platelet dysfunction and dysregulation in hemostasis and thrombosis. Clinically they provide critical guidance to the patient management and therapeutic evaluation.
Yingqi Zhang +8 more
doaj +1 more source
Biology Open, 2015 The formin family proteins are important regulators of actin polymerization that are involved in many cellular processes. However, little is known about their specific cellular localizations.
Xiaowei Shao +3 more
doaj +1 more source