Results 31 to 40 of about 35,268 (338)

A Review of in vitro Platforms for Understanding Cardiomyocyte Mechanobiology

Frontiers in Bioengineering and Biotechnology, 2019
Mechanobiology—a cell's interaction with its physical environment—can influence a myriad of cellular processes including how cells migrate, differentiate and proliferate.
Ian L. Chin, Livia Hool, Livia Hool, Yu Suk Choi   +3 more
doaj   +1 more source

From cellular to molecular mechanobiology

APL Bioengineering, 2020
Mechanobiology at the cellular level is concerned with what phenotypes that cells exhibit to maintain homeostasis in their normal physiological mechanical environment, as well as what phenotypical changes that cells have to make when their environment is
Cheng Zhu, Cho-yin Lee, Larry V. McIntire   +2 more
doaj   +1 more source

Leveraging mechanobiology and biophysical cues in lung organoids for studying lung development and disease

Frontiers in Chemical Engineering, 2023
Lung organoids have emerged as powerful tools for studying lung distal diseases by recapitulating the cellular diversity and microenvironment of the lung tissue. This review article highlights the advancements in leveraging mechanobiology and biophysical
Ziming Shao, Paolo De Coppi, Paolo De Coppi, Federica Michielin   +3 more
doaj   +1 more source

In silico bone mechanobiology: modeling a multifaceted biological system. [PDF]

, 2016
Mechanobiology, the study of the influence of mechanical loads on biological processes through signaling to cells, is fundamental to the inherent ability of bone tissue to adapt its structure in response to mechanical stimulation.
Ajubi, Anderson, Anderson, Anderson, Bailon-Plaza, Bakker, Barak, Barreto, Betts, Biot, Biot, Birmingham, Boccaccio, Bonewald, Burke, Burke, Byrne, Carlier, Carlier, Carter, Carter, Carter, Carter, Checa, Checa, Christen, Civelekoglu-Scholey, Claes, Claes, Claes, Cowin, Cowin, Drachman, Eyckmans, Forwood, Garcia-Aznar, Gardner, Geris, Geris, Geris, Geris, Geris, Giorgi, Giorgi, Gomez-Benito, Goodship, Gray, Gómez-Benito, Haj, Han, Harris, Heegaard, Huiskes, Humphrey, Isaksson, Isaksson, Isaksson, Isaksson, Isaksson, Ishihara, Ishihara, Jee, Kamioka, Kelly, Kenwright, Kenwright, Khayyeri, Khayyeri, Khayyeri, Klein-Nulend, Klein-Nulend, Knothe Tate, Knothe Tate, Knothe Tate, Knothe Tate, Kung, Lacroix, Lacroix, Lacroix, Lanyon, Lemaire, Lemaire, Lemaire, Lemonnier, Luterkort, Mak, Maquet, McGarry, McGarry, Meulen, Mikic, Mosley, Mullen, Mullen Conleth, Nicolella, Nowlan, O'Connor, Ogden, Ogden, Osborne, Owan, Pauwels, Pauwels, Peiffer, Perren, Piekarski, Portinaro, Prendergast, Price, Pérez, Rath Bonivtch, Reich, Reina-Romo, Reina-Romo, Renkawitz, Roddy, Ráliš, Sandino, Sansalone, Schaffler, Schulte, Shefelbine, Shefelbine, Steck, Sugiyama, Sugiyama, Varga, Vaughan, Vaughan, Vaughan, Vaughan, Verbruggen, Verbruggen, Verbruggen, Verbruggen Stefaan, Wang, Wang, Wang, Wang, Weinbaum, Westbroek, Wilson, Woo, You, You, Zeng, Zhao, Zhao   +147 more
core   +1 more source

Modelling cartilage mechanobiology [PDF]

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2003
The growth, maintenance and ossification of cartilage are fundamental to skeletal development and are regulated throughout life by the mechanical cues that are imposed by physical activities. Finite element computer analyses have been used to study the role of local tissue mechanics on endochondral ossification patterns, skeletal morphology and ...
Dennis R, Carter, Marcy, Wong
openaire   +2 more sources

mDia1 senses both force and torque during F-actin filament polymerization

Nature Communications, 2017
Formins are actin-polymerisation factors that are sensitive to force. Here the authors find that pulling force on an actin filament promoted faster actin polymerisation by the formin mDia1, and also found that the actin filament must be torsionally ...
Miao Yu, Xin Yuan, Chen Lu, Shimin Le, Ryo Kawamura, Artem K. Efremov, Zhihai Zhao, Michael M. Kozlov, Michael Sheetz, Alexander Bershadsky, Jie Yan   +10 more
doaj   +1 more source

Finite-element modelling of mechanobiological factors influencing sesamoid tissue morphology in the patellar tendon of an ostrich [PDF]

, 2017
The appearance and shape of sesamoid bones within a tendon or ligament wrapping around a joint are understood to be influenced by both genetic and epigenetic factors.
Carter DR, Dye S, Hogg DA, Lansdown AB, Macalister A, Vickaryous MK, Wren TA   +6 more
core   +1 more source

Trends in mechanobiology guided tissue engineering and tools to study cell-substrate interactions: a brief review

Biomaterials Research, 2023
Sensing the mechanical properties of the substrates or the matrix by the cells and the tissues, the subsequent downstream responses at the cellular, nuclear and epigenetic levels and the outcomes are beginning to get unraveled more recently.
A. Rajendran, D. Sankar, Sivashanmugam Amirthalingam, Hwan D. Kim, Jayakumar Rangasamy, Nathaniel S. Hwang   +5 more
semanticscholar   +1 more source

Quantitative structural mechanobiology of platelet-driven blood clot contraction. [PDF]

, 2017
Blood clot contraction plays an important role in prevention of bleeding and in thrombotic disorders. Here, we unveil and quantify the structural mechanisms of clot contraction at the level of single platelets.
Alber, Mark S, Kim, Oleg V, Litvinov, Rustem I, Weisel, John W   +3 more
core   +2 more sources

FRET and mechanobiology [PDF]

Integrative Biology, 2009
Since the development of green fluorescent protein (GFP) and other fluorescent proteins (FPs) with distinct colors, genetically-encoded probes and biosensors have been widely applied to visualize the molecular localization and activities in live cells.
Yingxiao, Wang, Ning, Wang
openaire   +2 more sources