Results 11 to 20 of about 35,268 (338)

Mechanobiology of Adipocytes

Biology
The growing obesity epidemic necessitates increased research on adipocyte and adipose tissue function and disease mechanisms that progress obesity. Historically, adipocytes were viewed simply as storage for excess energy.
Sean P. Blade, Dylan J. Falkowski, Sarah N. Bachand, Steven J. Pagano, LiKang Chin   +4 more
doaj   +4 more sources

Endothelial mechanobiology [PDF]

APL Bioengineering, 2020
Lining the luminal surface of the vasculature, endothelial cells (ECs) are in direct contact with and differentially respond to hemodynamic forces depending on their anatomic location.
Ming He, Marcy Martin, Traci Marin, Zhen Chen, Brendan Gongol   +4 more
doaj   +3 more sources

Engineered hydrogels for mechanobiology

Nature Reviews Methods Primers, 2022
Cells’ local mechanical environment can be as important in guiding cellular responses as many well-characterized biochemical cues. Hydrogels that mimic the native extracellular matrix can provide these mechanical cues to encapsulated cells, allowing for ...
U. Blache, Eden M. Ford, B. Ha, Laura Rijns, Ovijit Chaudhuri, P. Dankers, April M. Kloxin, J. Snedeker, E. Gentleman   +8 more
semanticscholar   +3 more sources

Stem cell mechanobiology [PDF]

Journal of Cellular Biochemistry, 2010
Stem cells are undifferentiated cells that are capable of proliferation, self-maintenance and differentiation towards specific cell phenotypes. These processes are controlled by a variety of cues including physicochemical factors associated with the ...
Bader, Dan L., Campbell, Jonathan J., Knight, Martin M., Lee, David A.   +3 more
core   +5 more sources

Keratocyte mechanobiology [PDF]

Experimental Eye Research, 2020
In vivo, corneal keratocytes reside within a complex 3D extracellular matrix (ECM) consisting of highly aligned collagen lamellae, growth factors, and other extracellular matrix components, and are subjected to various mechanical stimuli during developmental morphogenesis, fluctuations in intraocular pressure, and wound healing.
W. Matthew Petroll, Victor D. Varner, David W. Schmidtke   +2 more
openalex   +4 more sources

Mechanobiology of portal hypertension

JHEP Reports, 2023
Summary The interplay between mechanical stimuli and cellular mechanobiology orchestrates the physiology of tissues and organs in a dynamic balance characterized by constant remodelling and adaptative processes. Environmental mechanical properties can be
É. Felli, Sonia E Selicean, Sergi Guixé-Muntet, Cong Wang, J. Bosch, A. Berzigotti, J. Gracia‐Sancho   +6 more
semanticscholar   +4 more sources

Editorial: Cardiovascular Mechanobiology [PDF]

Frontiers in Physiology, 2022
Markus Hecker, Dirk J. Duncker
doaj   +4 more sources

The mechanobiology of fibroblast activation in disease

APL Bioengineering
Fibroblasts play crucial roles in wound healing, cancer, and fibrosis. Many aspects of these roles are driven by the process known as fibroblast activation.
Yeji Chang, Jia Wen Nicole Lee, Andrew W. Holle   +2 more
openalex   +2 more sources

Osteocyte Mechanobiology [PDF]

Current Osteoporosis Reports, 2017
Over the past decades, osteocytes have emerged as mechano-sensors of bone and master regulators of bone homeostasis. This article summarizes latest research and progress made in understanding osteocyte mechanobiology and critically reviews tools currently available to study these cells.Whereas increased mechanical forces promote bone formation ...
Yuhei, Uda, Ehab, Azab, Ningyuan, Sun, Chao, Shi, Paola Divieti, Pajevic   +4 more
openaire   +2 more sources

Unlocking the therapeutic potential of cellular mechanobiology. [PDF]

Sci Adv
Mechanobiology is a rapidly advancing field at the intersection of biology, physics, and engineering that reveals how mechanical forces shape cellular behavior, tissue architecture, and disease progression.
Kalukula Y, Ciccone G, Mohammed D, Procès A, Versaevel M, Deridoux A, Ergot L, Barbier Z, Mansy M, Aucouturier R, Tranzer R, Surin M, Gabriele S, Luciano M.   +13 more
europepmc   +2 more sources