Results 11 to 20 of about 12,439 (207)
Endothelial mechanobiology [PDF]
APL Bioengineering, 2020 Lining the luminal surface of the vasculature, endothelial cells (ECs) are in direct contact with and differentially respond to hemodynamic forces depending on their anatomic location.
Ming He +4 more
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Mechanobiology of cancerogenesis
Klinicka onkologie, 2021 Within the tumour microenvironment, tumour cells are exposed to different mechanical stimuli such as compression stress, cell-cell and cell-extracellular matrix traction forces, interstitial fluid pressure, and shear stress. Cells actively sense and process this information by the mechanism of mechanotransduction to make decisions about their growth ...
Martina, Raudenská +3 more
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Mechanobiology of the meniscus [PDF]
Journal of Biomechanics, 2015 The meniscus plays a critical biomechanical role in the knee, providing load support, joint stability, and congruity. Importantly, growing evidence indicates that the mechanobiologic response of meniscal cells plays a critical role in the physiologic, pathologic, and repair responses of the meniscus.
McNulty, Amy L, Guilak, Farshid
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The Mechanobiology of Aging [PDF]
Annual Review of Biomedical Engineering, 2015 Aging is a complex, multifaceted process that induces a myriad of physiological changes over an extended period of time. Aging is accompanied by major biochemical and biomechanical changes at macroscopic and microscopic length scales that affect not only tissues and organs but also cells and subcellular organelles.
Jude M, Phillip +3 more
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Keratocyte mechanobiology [PDF]
Experimental Eye Research, 2020 In vivo, corneal keratocytes reside within a complex 3D extracellular matrix (ECM) consisting of highly aligned collagen lamellae, growth factors, and other extracellular matrix components, and are subjected to various mechanical stimuli during developmental morphogenesis, fluctuations in intraocular pressure, and wound healing.
W Matthew, Petroll +2 more
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Mechanobiology of Ciliogenesis [PDF]
BioScience, 2014 Cilia are force-generating and -sensing organelles that serve as mechanical interfaces between the cell and the extracellular environment. Cilia are present in tissues that adaptively respond to mechanical loading and fluid flow, and defects in ciliary function can lead to diseases affecting these tissues.
Ishikawa, Hiroaki, Marshall, Wallace F
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Integrative Biology, 2009 Since the development of green fluorescent protein (GFP) and other fluorescent proteins (FPs) with distinct colors, genetically-encoded probes and biosensors have been widely applied to visualize the molecular localization and activities in live cells.
Yingxiao, Wang, Ning, Wang
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Osteocyte Mechanobiology [PDF]
Current Osteoporosis Reports, 2017 Over the past decades, osteocytes have emerged as mechano-sensors of bone and master regulators of bone homeostasis. This article summarizes latest research and progress made in understanding osteocyte mechanobiology and critically reviews tools currently available to study these cells.Whereas increased mechanical forces promote bone formation ...
Yuhei, Uda +4 more
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A Review of in vitro Platforms for Understanding Cardiomyocyte Mechanobiology
Frontiers in Bioengineering and Biotechnology, 2019 Mechanobiology—a cell's interaction with its physical environment—can influence a myriad of cellular processes including how cells migrate, differentiate and proliferate.
Ian L. Chin +3 more
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From cellular to molecular mechanobiology
APL Bioengineering, 2020 Mechanobiology at the cellular level is concerned with what phenotypes that cells exhibit to maintain homeostasis in their normal physiological mechanical environment, as well as what phenotypical changes that cells have to make when their environment is
Cheng Zhu +2 more
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