Results 21 to 30 of about 18,551 (276)
Background The stress fibers are prominent organization of actin filaments that perform important functions in cellular processes such as migration, polarization, and traction force generation, and whose collective organization reflects the physiological
Zhen Zhang +2 more
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Foreword to the special issue on Bone and cartilage mechanobiology across the scales [PDF]
The idea for this special issue on “Bone and Cartilage Mechanobiology Across the Scales” in the journal Biomechanics and Modeling in Mechanobiology is based on a series of high-quality presentations at two minisymposia at the 11th World Congress on ...
Pivonka, P. +5 more
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A Review of in vitro Platforms for Understanding Cardiomyocyte Mechanobiology
Mechanobiology—a cell's interaction with its physical environment—can influence a myriad of cellular processes including how cells migrate, differentiate and proliferate.
Ian L. Chin +3 more
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From cellular to molecular mechanobiology
Mechanobiology at the cellular level is concerned with what phenotypes that cells exhibit to maintain homeostasis in their normal physiological mechanical environment, as well as what phenotypical changes that cells have to make when their environment is
Cheng Zhu +2 more
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mDia1 senses both force and torque during F-actin filament polymerization
Formins are actin-polymerisation factors that are sensitive to force. Here the authors find that pulling force on an actin filament promoted faster actin polymerisation by the formin mDia1, and also found that the actin filament must be torsionally ...
Miao Yu +10 more
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Lung organoids have emerged as powerful tools for studying lung distal diseases by recapitulating the cellular diversity and microenvironment of the lung tissue. This review article highlights the advancements in leveraging mechanobiology and biophysical
Ziming Shao +3 more
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Optogenetic control of YAP can enhance the rate of wound healing
Background Tissues need to regenerate to restore function after injury. Yet, this regenerative capacity varies significantly between organs and between species.
Pearlyn Jia Ying Toh +2 more
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Germline cells in many species are fused to form a syncytium but the mechanics behind the maintenance of these structures are poorly defined. Here, the authors propose an inner contractile actomyosin corset provides a supportive framework to maintain ...
Agarwal Priti +6 more
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Mechanobiology of the Mitotic Spindle [PDF]
The mitotic spindle is a microtubule-based assembly that separates the chromosomes during cell division. As the spindle is basically a mechanical micro machine, the understanding of its functioning is constantly motivating the development of experimental approaches based on mechanical perturbations, which are complementary to and work together with the
Pavin, Nenad, Tolić, Iva M.
openaire +4 more sources
Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion
Fiolopodia are involved in cell migration and their attachment to the ECM is mediated by integrin receptors. Here the authors show that myosin X induced filipodia adhesion to fibronectin requires activity of myosin IIA at the filopodium base and formin ...
N. O. Alieva +12 more
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