Results 21 to 30 of about 18,551 (276)

An integrated enhancement and reconstruction strategy for the quantitative extraction of actin stress fibers from fluorescence micrographs

open access: yesBMC Bioinformatics, 2017
Background The stress fibers are prominent organization of actin filaments that perform important functions in cellular processes such as migration, polarization, and traction force generation, and whose collective organization reflects the physiological
Zhen Zhang   +2 more
doaj   +1 more source

Foreword to the special issue on Bone and cartilage mechanobiology across the scales [PDF]

open access: yes, 2016
The idea for this special issue on “Bone and Cartilage Mechanobiology Across the Scales” in the journal Biomechanics and Modeling in Mechanobiology is based on a series of high-quality presentations at two minisymposia at the 11th World Congress on ...
Pivonka, P.   +5 more
core   +1 more source

A Review of in vitro Platforms for Understanding Cardiomyocyte Mechanobiology

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
Mechanobiology—a cell's interaction with its physical environment—can influence a myriad of cellular processes including how cells migrate, differentiate and proliferate.
Ian L. Chin   +3 more
doaj   +1 more source

From cellular to molecular mechanobiology

open access: yesAPL Bioengineering, 2020
Mechanobiology at the cellular level is concerned with what phenotypes that cells exhibit to maintain homeostasis in their normal physiological mechanical environment, as well as what phenotypical changes that cells have to make when their environment is
Cheng Zhu   +2 more
doaj   +1 more source

mDia1 senses both force and torque during F-actin filament polymerization

open access: yesNature Communications, 2017
Formins are actin-polymerisation factors that are sensitive to force. Here the authors find that pulling force on an actin filament promoted faster actin polymerisation by the formin mDia1, and also found that the actin filament must be torsionally ...
Miao Yu   +10 more
doaj   +1 more source

Leveraging mechanobiology and biophysical cues in lung organoids for studying lung development and disease

open access: yesFrontiers in Chemical Engineering, 2023
Lung organoids have emerged as powerful tools for studying lung distal diseases by recapitulating the cellular diversity and microenvironment of the lung tissue. This review article highlights the advancements in leveraging mechanobiology and biophysical
Ziming Shao   +3 more
doaj   +1 more source

Optogenetic control of YAP can enhance the rate of wound healing

open access: yesCellular & Molecular Biology Letters, 2023
Background Tissues need to regenerate to restore function after injury. Yet, this regenerative capacity varies significantly between organs and between species.
Pearlyn Jia Ying Toh   +2 more
doaj   +1 more source

Syncytial germline architecture is actively maintained by contraction of an internal actomyosin corset

open access: yesNature Communications, 2018
Germline cells in many species are fused to form a syncytium but the mechanics behind the maintenance of these structures are poorly defined. Here, the authors propose an inner contractile actomyosin corset provides a supportive framework to maintain ...
Agarwal Priti   +6 more
doaj   +1 more source

Mechanobiology of the Mitotic Spindle [PDF]

open access: yesDevelopmental Cell, 2021
The mitotic spindle is a microtubule-based assembly that separates the chromosomes during cell division. As the spindle is basically a mechanical micro machine, the understanding of its functioning is constantly motivating the development of experimental approaches based on mechanical perturbations, which are complementary to and work together with the
Pavin, Nenad, Tolić, Iva M.
openaire   +4 more sources

Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion

open access: yesNature Communications, 2019
Fiolopodia are involved in cell migration and their attachment to the ECM is mediated by integrin receptors. Here the authors show that myosin X induced filipodia adhesion to fibronectin requires activity of myosin IIA at the filopodium base and formin ...
N. O. Alieva   +12 more
doaj   +1 more source

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