Results 21 to 30 of about 35,268 (338)
Biomechanics and mechanobiology of the bone matrix
Bone Research, 2022 The bone matrix plays an indispensable role in the human body, and its unique biomechanical and mechanobiological properties have received much attention.
Chunyang Ma +3 more
semanticscholar +1 more source
Actomyosin contractility as a mechanical checkpoint for cell state transitions
Scientific Reports, 2022 Cell state transitions induced by mechano-chemical cues result in a heterogeneous population of cell states. While much of the work towards understanding the origins of such heterogeneity has focused on the gene regulatory mechanisms, the contribution of
Saradha Venkatachalapathy +3 more
doaj +1 more source
Endothelial mechanobiology in atherosclerosis.
Cardiovascular Research, 2023 Cardiovascular disease (CVD) is a serious health challenge, causing more deaths world-wide than cancer. The vascular endothelium, which forms the inner lining of blood vessels, plays a central role in maintaining vascular integrity and homeostasis and is
Xiaoli Wang +4 more
semanticscholar +1 more source
Mechanobiology of Ciliogenesis [PDF]
BioScience, 2014 Cilia are force-generating and -sensing organelles that serve as mechanical interfaces between the cell and the extracellular environment. Cilia are present in tissues that adaptively respond to mechanical loading and fluid flow, and defects in ciliary function can lead to diseases affecting these tissues.
Ishikawa, Hiroaki, Marshall, Wallace F
openaire +4 more sources
Enhanced tumor cell killing by ultrasound after microtubule depolymerization
Bioengineering & Translational Medicine, 2021 Recent studies show that tumor cells are vulnerable to mechanical stresses and undergo calcium‐dependent apoptosis (mechanoptosis) with mechanical perturbation by low‐frequency ultrasound alone.
Aditi Singh +6 more
doaj +1 more source
Neural regulation of cancer: from mechanobiology to inflammation. [PDF]
, 2016 Despite recent progress in cancer research, the exact nature of malignant transformation and its progression is still not fully understood. Particularly metastasis, which accounts for most cancer death, is a very complex process, and new treatment ...
Kim, Tae-Hyung +2 more
core +2 more sources
Red Blood Cells from Individuals with Abdominal Obesity or Metabolic Abnormalities Exhibit Less Deformability upon Entering a Constriction. [PDF]
, 2016 Abdominal obesity and metabolic syndrome (MS) are multifactorial conditions associated with increased risk of cardiovascular disease and type II diabetes mellitus.
Mancuso, Jordan E +4 more
core +11 more sources
BMC Bioinformatics, 2017 Background The stress fibers are prominent organization of actin filaments that perform important functions in cellular processes such as migration, polarization, and traction force generation, and whose collective organization reflects the physiological
Zhen Zhang +2 more
doaj +1 more source
Mechanical and Systems Biology of Cancer [PDF]
, 2018 Mechanics and biochemical signaling are both often deregulated in cancer, leading to cancer cell phenotypes that exhibit increased invasiveness, proliferation, and survival.
Bakal, Chris +2 more
core +3 more sources
Mechanobiology of cancerogenesis
Klinicka onkologie, 2021 Within the tumour microenvironment, tumour cells are exposed to different mechanical stimuli such as compression stress, cell-cell and cell-extracellular matrix traction forces, interstitial fluid pressure, and shear stress. Cells actively sense and process this information by the mechanism of mechanotransduction to make decisions about their growth ...
Martina, Raudenská +3 more
openaire +2 more sources