Results 81 to 90 of about 35,268 (338)
Advanced Healthcare Materials, EarlyView.Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan +9 more
wiley +1 more source
Nature CommunicationsChromatin-lamina interactions regulate gene activity by forming lamina-associated domains (LADs), which contribute to cellular identity through gene repression.
Monika Dhankhar +9 more
doaj +1 more source
Mechanobiology: Shaping the future of cellular form and function.
CellMechanobiology-the field studying how cells produce, sense, and respond to mechanical forces-is pivotal in the analysis of how cells and tissues take shape in development and disease.
Celeste M. Nelson +10 more
semanticscholar +1 more source
Osteosarcoma mechanobiology and therapeutic targets
British Journal of Pharmacology, 2021 Osteosarcoma is one of the most common primary tumours of the bone, with a 5‐year survival rate of less than 20% after the development of metastases. Osteosarcoma is highly predisposed in Paget's disease of the bone, and both have common characteristic ...
Z. Shoaib, T. Fan, J. Irudayaraj
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang +13 more
wiley +1 more source
Integrin-Matrix Clusters Form Podosome-like Adhesions in the Absence of Traction Forces
Cell Reports, 2013 Matrix-activated integrins can form different adhesion structures. We report that nontransformed fibroblasts develop podosome-like adhesions when spread on fluid Arg-Gly-Asp peptide (RGD)-lipid surfaces, whereas they habitually form focal adhesions on ...
Cheng-han Yu +6 more
doaj +1 more source
Characterisation of the mechanobiology of stents in vitro [PDF]
, 2014 This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014) +6 more
core
Three scales asymptotic homogenization and its application to layered hierarchical hard tissues [PDF]
, 2018 In the present work a novel multiple scales asymptotic homogenization approach is proposed to study the effective properties of hierarchical composites with periodic structure at different length scales.
Bravo-Castillero, Julián +8 more
core +2 more sources
International Journal of Molecular Sciences, 2023 Low back pain is an extremely common condition with severe consequences. Among its potential specific causes, degenerative disc disease (DDD) is one of the most frequently observed.
A. Ruffilli +9 more
semanticscholar +1 more source
Microengineered Gradient Hydrogels for Mechanobiology
Advanced Healthcare Materials, EarlyView.Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong +4 more
wiley +1 more source