Results 71 to 80 of about 18,551 (276)

Exploring the Dynamic Concept of Mechanobiology in Regenerative Rehabilitation: A Narrative Review [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Physical therapists, equipped with unique diagnostic and treatment capabilities, play a pivotal role in advancing regenerative medicine. The present review explores the integration of mechanotherapy and mechanical techniques in physiotherapy, shedding ...
Purva Gulrandhe   +3 more
doaj   +1 more source

Systemic Nanomechanical Single‐Cell Profiling Reveals Mechanophenotype Transitions Under Therapeutic Perturbation

open access: yesAdvanced Science, EarlyView.
Single‐cell mechanomics demonstrates that pharmacological perturbation changes cytoskeletal and cortical structure, suppressing cancer cell invasiveness. By integrating atomic force microscopy (AFM)‐based cortical measurements with stimulated emission depletion (STED)‐resolved adhesion and cytoskeletal organization, this approach identifies nanoscale ...
Minhee Ku   +4 more
wiley   +1 more source

Chengzhulab/Mechanobiology-of-CD40: CD40 mechanobiology

open access: yes
Mechanobiology-of ...
vaglino, Chengzhulab
core   +1 more source

Single cell, super-resolution imaging reveals an acid pH-dependent conformational switch in SsrB regulates SPI-2

open access: yeseLife, 2019
After Salmonella is phagocytosed, it resides in an acidic vacuole. Its cytoplasm acidifies to pH 5.6; acidification activates pathogenicity island 2 (SPI-2).
Andrew Tze Fui Liew   +6 more
doaj   +1 more source

From Displacement to Angle: Diamond‐Based 3D Rotation Sensing for High‐Precision Cellular Force Measurement

open access: yesAdvanced Science, EarlyView.
Cellular forces are traditionally inferred from displacement measurements, which lack rotational information and are constrained by linear model assumptions. This work replaces displacement with rotational angle for the fundamental mechanical readout.
Linjie Ma   +8 more
wiley   +1 more source

Stimuli-responsive biomaterials for cardiac tissue engineering and dynamic mechanobiology

open access: yesAPL Bioengineering, 2021
Since the term “smart materials” was put forward in the 1980s, stimuli-responsive biomaterials have been used as powerful tools in tissue engineering, mechanobiology, and clinical applications.
Huaiyu Shi, Chenyan Wang, Zhen Ma
doaj   +1 more source

Mechanobiology of the Nucleolus

open access: yesBiology of the Cell
ABSTRACT Ribosome biogenesis is an essential and energy‐demanding process required to maintain cellular proteostasis. The nucleolus, which orchestrates this vital process, assembles as a nuclear condensate and exhibits remarkable plasticity in its structure, function, and protein composition.
Shetty, Yuthika, Dolega, Monika
openaire   +3 more sources

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

open access: yesAdvanced Science, EarlyView.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu   +4 more
wiley   +1 more source

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