Results 101 to 110 of about 18,551 (276)
Biology Open, 2016 Cell migration is a highly dynamic process that plays pivotal roles in both physiological and pathological processes. We have previously reported that p130Cas supports cell migration through the binding to Src as well as phosphorylation-dependent ...
Zhihai Zhao +6 more
doaj +1 more source
Advanced Science, EarlyView.Tendon interfascicular and fascicular matrix cells are isolated and cultured, revealing distinct phenotypes and mechanosensitive responses. Interfascicular matrix cells exhibit marked stiffness‐dependent phenotypic plasticity, whereas fascicular matrix cells remain comparatively stable.
S. E. Grossemy +10 more
wiley +1 more source
THREE-DIMENSIONAL CELL INTERCALATION DRIVES DROSOPHILA GERMBAND EXTENSION
, 2017 Ph.DPH.D.
SUN ZIJUN
core
NucleusThe immune system functions within tissue microenvironments of mechanical and geometrical constraints. Within these constraints, immune cells must rapidly move and execute effector functions to regulate innate and adaptive immunity.
Jörg Renkawitz +5 more
doaj +1 more source
Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy
Advanced Science, EarlyView.A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao +10 more
wiley +1 more source
SINGLE MOLECULE STUDIES OF DNA-H-NS INTERACTIONS IN PROKARYOTIC CELLS
, 2017 Ph.DPH.D.
RANJIT S GULVADY
core
FUNCTIONAL CHARACTERIZATION OF FORMIN-DEPENDENT ACTIN POLYMERIZATION AT ADHERENS JUNCTIONS [PDF]
, 2016 Ph.DPH.D.
MEGHA VAMAN RAO
core
Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading
Advanced Science, EarlyView.Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong +5 more
wiley +1 more source
Mechanobiological feedback loops and quantitative decision thresholds in organ fibrosis: Translational principles for antifibrotic therapy. [PDF]
J Cell Commun SignalMultiorgan fibrosis arises when chronic injury activates fibroblasts and remodels extracellular matrix, whose increasing stiffness sustains disease through mechanotransduction pathways. Bidirectional cellular‐matrix feedback operates across lung, heart, liver, and kidney.
Lonardo A, Weiskirchen R.
europepmc +2 more sources
Polycystins in disease mechanobiology
Journal of Cellular Biochemistry, 2018 AbstractDistorted mechanotransduction represents the molecular hallmark of disease mechanobiology and is displayed with common features during the development of various pathophysiologies. Polycystins constitute a family of mechanosensitive proteins that facilitate pathogenic signal transduction mechanisms.
Antonios N. Gargalionis +2 more
openaire +3 more sources