Results 111 to 120 of about 12,439 (207)

The epidermis coordinates multi-scale symmetry breaking in chiral root growth

open access: yesNature Communications
Twisted growth serves myriad adaptive functions in plants. Unlike animal motions, plant motions require symmetry breaking during growth and typically involve microtubule-related genes.
Natasha Nolan   +9 more
doaj   +1 more source

A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair

open access: yesAdvanced Science, Volume 13, Issue 43, 3 August 2026.
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao   +14 more
wiley   +1 more source

Deep Learning‐Assisted Coherent Raman Scattering Microscopy

open access: yesAdvanced Intelligent Discovery, Volume 2, Issue 4, August 2026.
The analytical capabilities of coherent Raman scattering microscopy are augmented through deep learning integration. This synergistic paradigm improves fundamental performance via denoising, deconvolution, and hyperspectral unmixing. Concurrently, it enhances downstream image analysis including subcellular localization, virtual staining, and clinical ...
Jianlin Liu   +4 more
wiley   +1 more source

Mechanobiology [PDF]

open access: yesJournal of The Royal Society Interface, 2010
Chwee Teck Lim   +2 more
openaire   +1 more source

Tensile Stimulation in Biorelevant Culture Conditions Enhances MSC and TPSC Tenogenesis on Aligned Electrospun Scaffolds

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 8, August 2026.
Biomimetic electrospun scaffold incorporating GDF‐7‐loaded mesoporous silica nanoparticles, combined with mechanical stimulation and physiological oxygen tension, guides tenogenic differentiation of mesenchymal stromal cell and tendon progenitor stem cell. This integrated approach enhances cell proliferation, matrix deposition, and tendon‐specific gene
Vera Citro   +3 more
wiley   +1 more source

Mechanobiology of myeloid cells

open access: yesCurrent Opinion in Cell Biology
Tissue-resident myeloid cells sense and transduce mechanical signals such as stiffness, stretch and compression. In the past two years, our understanding of the mechanosensitive signalling pathways in myeloid cells has significantly expanded. Moreover, it is increasingly clear which mechanical signals induce myeloid cells towards a pro- or anti ...
Janssen, Eline   +3 more
openaire   +4 more sources

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 8, August 2026.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei   +2 more
wiley   +1 more source

The Mechanobiology of Adipocyte Hypertrophy: Cytoskeletal Remodelling as a Driver of Insulin Resistance in Obesity

open access: yesCell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT Adipocyte hypertrophy poses an important mechanical challenge—adipocytes can increase in volume up to a thousand‐fold while still maintaining their structural integrity. Although lipid metabolism is well studied, little is known about the cytoskeletal adaptations that are required to accommodate this expansion and the resulting pathological ...
Dhakshmi Sasankan, Renu Mohan
wiley   +1 more source

Hippo Pathway Regulation and Microenvironmental Cues Governing Human MSC Transition to Cancer‐Associated Fibroblasts

open access: yesJournal of Cellular Physiology, Volume 241, Issue 8, August 2026.
ABSTRACT Cancer‐associated fibroblasts (CAFs) are key drivers of tumor progression. This study examined how three‐dimensional (3D) culture, hypoxia, and cancer‐derived soluble factors influence the transformation of human mesenchymal stem cells (hMSCs) into inflammatory CAFs (iCAFs). hMSCs from bone marrow, placenta, and chorion were cultured in 2D, in
Pimjai Chingsuwanrote   +7 more
wiley   +1 more source

Targeted immunotherapy rescues pulmonary fibrosis by reducing activated fibroblasts and regulating alveolar cell profile

open access: yesNature Communications
Idiopathic pulmonary fibrosis (IPF) is a severe lung disease occurring throughout the world; however, few clinical therapies are available for treating this disorder.
Jing Yan   +6 more
doaj   +1 more source

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