Results 131 to 140 of about 18,551 (276)

FUNCTIONAL CHARACTERIZATION OF THE ACTIN-BUNDLING PROTEIN PLASTIN IN C. ELEGANS EARLY EMBRYOGENESIS

, 2017
Ph.DPH.D.
DING WEI YUNG
core  

Dual‐Component Spidroin‐Based Hydrogels: A Mechanically Tunable Platform for 2D and 3D Cell Culture

Small, EarlyView.
A dual‐component recombinant spider silk hydrogel platform was developed by combining NT2RepCT with a bioactive vitronectin‐functionalized spidroin domain. The hydrogels self‐assemble under physiological conditions, exhibit tunable mechanical properties, and support 2D and 3D cell culture, providing a versatile platform for mechanobiological studies ...
Sanna Korpela, Urmimala Chatterjee, Gabriele Greco, Benjamin Schmuck, Rakesh Kumar, Olga Shilkova, Cecilia Götherström, Anna Rising, Teemu O. Ihalainen   +8 more
wiley   +1 more source

DECODING MORPHOGEN-INSTRUCTED DEVELOPMENTAL PRECISION

, 2018
Ph.DPH.D.
HUANG ANQI
core  

Mechano‐Chemical Coordination of Nanoparticle‐Based Artificial Antigen‐Presenting Cells Synergistically Tunes T Cell Activation and Expansion Phenotypes

Small, EarlyView.
Mechanically distinct nano artificial antigen‐presenting cells with independently controlled antibody density are used to reveal how physical and biochemical cues jointly regulate human T‐cell activation. Increasing stiffness and antibody density accelerates activation, enhances expansion, and promotes effector‐associated differentiation, whereas ...
Zichao Guo, Fei Hou, Yali Zhang, Zilin Ye, Yang Li, Supun Ranaweera, Yue Hui, Chun‐Xia Zhao   +7 more
wiley   +1 more source

Mechanobiology of myeloid cells

Current Opinion in Cell Biology
Tissue-resident myeloid cells sense and transduce mechanical signals such as stiffness, stretch and compression. In the past two years, our understanding of the mechanosensitive signalling pathways in myeloid cells has significantly expanded. Moreover, it is increasingly clear which mechanical signals induce myeloid cells towards a pro- or anti ...
Janssen, Eline, van den Dries, Koen, Ventre, Maurizio, Cambi, Alessandra   +3 more
openaire   +4 more sources

Two‐Dimensional Materials For Lateral Flow Assays: A Critical Review of Functional Roles and Translational Challenges

VIEW, EarlyView.
2D nanosheets, with large surface area, excellent optical/electrical properties, and high specificity, combine with lateral flow assay strips to enable rapid, readable detection, boosting the strips’ development and applications. Abstract Lateral flow assays (LFAs) are widely used for point‐of‐care diagnostics, but their detection capability remains ...
Weimin Xu, Ruping Liu, Na Gao, Jianxiao Zhu, Haowen Jiang, Shouzheng Jiao, Zhicheng Sun, Kai Shen, Gaolian Xu, Minghua Du, Ziyan Li, Yang Wang   +11 more
wiley   +1 more source

STRUCTURE AND ASSEMBLY OF SINGAPORE GROUPER INDOVIRUS [PDF]

, 2015
Ph.DPH.D.
LIU YANG
core  

Four‐dimensional immuno‐mechanobiomaterials: Dynamic material cues that program host response to prevent fibrosis and enable regeneration

VIEW, EarlyView.
Dynamic immuno‐mechanobiomaterials with time‐programmed mechanical adaptation orchestrate host responses through precise mechanotransduction and immune‐stromal regulation. These adaptive biomaterials minimize mechanical mismatch, attenuate the forign dy response and fibrosis, promote angiogenesis and controlled extracellular matrix remodeling, and ...
Gobinath Vellapalayam Manoharan, Kathirvel Ayyaswamy, Parthasarathy Vellaichamy, Nagarajan Deivanayagam Pillai, Rithik Gobinath   +4 more
wiley   +1 more source

Mechanomemory after short episodes of intermittent stresses induces YAP translocation via increasing F-actin

APL Bioengineering
How forces and mechanics influence and regulate living cells remains elusive. Mechanomemory, the response to a mechanical perturbation that persists after the perturbation is removed, is believed to be a key to understanding the impact of forces and ...
Fazlur Rashid, Elvis Njoki, Sadia Amin Kabbo, Ning Wang   +3 more
doaj   +1 more source

Proprioception drives tension wood formation for autotropic straightening and postural control in trees

New Phytologist, EarlyView.
Proprioception controls trunk straightness in trees through opposite tension wood formation. A spherical growth chamber (a), combined with a two‐dimensional rotating clinostat (b2), suppresses gravi‐ and phototropic sensing. The tree is first tilted horizontally (b1), triggering upward gravitropic bending, actuated by tension wood formation on the ...
Alexandre Caulus, Félix P. Hartmann, Éric Badel, Stéphane Ploquin, Nicole Brunel‐Michac, Julien Ruelle, Mélanie Decourteix, Bruno Moulia   +7 more
wiley   +1 more source