Results 1 to 10 of about 5,456 (165)

Morphology and ultrastructure of external sense organs of <i>Drosophila</i> larvae. [PDF]

Elife
Sensory perception is the ability through which an organism is able to process sensory stimuli from the environment. This stimulus is transmitted from the peripheral sensory organs to the central nervous system, where it is interpreted.
Richter V, Rist A, Kislinger G, Laumann M, Schoofs A, Miroschnikow A, Pankratz MJ, Cardona A, Thum AS.   +8 more
europepmc   +2 more sources

Induced Proprioceptor and Low-Threshold Mechanoreceptor Neurons Derived from Human Pluripotent Stem Cells Exhibit Distinct Functional Mechanosensory Properties. [PDF]

Adv Sci (Weinh)
Mechanosensory neurons are a specialized class of neurons that detect mechanical stimuli elicited by external or internal body forces. Two major subclasses of mechanosensory neurons reside within the dorsal root ganglia; proprioceptor neurons (PN) that ...
Hulme AJ, Finol-Urdaneta RK, McArthur JR, Marzano NR, Maksour S, Thind A, Guo Y, Kaul D, Maddock M, Friedrich O, Martinac B, Adams DJ, Dottori M.   +12 more
europepmc   +2 more sources

Tendon mechanobiology in the context of tendon biofabrication. [PDF]

Front Bioeng Biotechnol
Tendons are often affected by injuries or tendinopathies, resulting in serious and long-lasting impairments. The repair capacity is very low with a high risk of rerupture.
Gögele C, Pattappa G, Tempfer H, Docheva D, Schulze-Tanzil G.   +4 more
europepmc   +2 more sources

Mechanosensation mediates volume adaptation of cardiac cells and spheroids in 3D

Materials Today Bio, 2022
With the adoption of 3-dimensional (3D) cell culture for in vitro modelling of cardiac function and regenerative medicine applications, there is an increased need to understand cardiomyocyte mechanosensation in 3D.
Ian L. Chin, Sebastian E. Amos, Ji Hoon Jeong, Livia Hool, Yongsung Hwang, Yu Suk Choi   +5 more
doaj   +1 more source

Drosophila mechanical nociceptors preferentially sense localized poking

eLife, 2022
Mechanical nociception is an evolutionarily conserved sensory process required for the survival of living organisms. Previous studies have revealed much about the neural circuits and sensory molecules in mechanical nociception, but the cellular ...
Zhen Liu, Meng-Hua Wu, Qi-Xuan Wang, Shao-Zhen Lin, Xi-Qiao Feng, Bo Li, Xin Liang   +6 more
doaj   +1 more source

Loss-of-Function Piezo1 Mutations Display Altered Stability Driven by Ubiquitination and Proteasomal Degradation

Frontiers in Pharmacology, 2021
Missense mutations in the gene that encodes for the mechanically-gated ion channel Piezo1 have been linked to a number of diseases. Gain-of-function variants are linked to a hereditary anaemia and loss-of-function variants have been linked to generalized
Zijing Zhou, Jinyuan Vero Li, Boris Martinac, Boris Martinac, Charles D. Cox, Charles D. Cox   +5 more
doaj   +1 more source

Control of feeding by Piezo-mediated gut mechanosensation in Drosophila

eLife, 2021
Across animal species, meals are terminated after ingestion of large food volumes, yet underlying mechanosensory receptors have so far remained elusive. Here, we identify an essential role for Drosophila Piezo in volume-based control of meal size.
Soohong Min, Yangkyun Oh, Pushpa Verma, Samuel C Whitehead, Nilay Yapici, David Van Vactor, Greg SB Suh, Stephen Liberles   +7 more
doaj   +1 more source

Physiological responses of mechanosensory systems in the head of larval zebrafish (Danio rerio)

Frontiers in Robotics and AI, 2023
The lateral line system of zebrafish consists of the anterior lateral line, with neuromasts distributed on the head, and the posterior lateral line, with neuromasts distributed on the trunk.
Nils Brehm, Nils Wenke, Keshia Glessner, Melanie Haehnel-Taguchi   +3 more
doaj   +1 more source

A novel mechanosensitive channel controls osmoregulation, differentiation, and infectivity in Trypanosoma cruzi

eLife, 2021
The causative agent of Chagas disease undergoes drastic morphological and biochemical modifications as it passes between hosts and transitions from extracellular to intracellular stages.
Noopur Dave, Ugur Cetiner, Daniel Arroyo, Joshua Fonbuena, Megna Tiwari, Patricia Barrera, Noelia Lander, Andriy Anishkin, Sergei Sukharev, Veronica Jimenez   +9 more
doaj   +1 more source

Highly Stretchable Graphene Scrolls Transistors for Self-Powered Tribotronic Non-Mechanosensation Application

Nanomaterials, 2023
Owing to highly desired requirements in advanced disease diagnosis, therapy, and health monitoring, noncontact mechanosensation active matrix has drawn considerable attention.
Yanfang Meng
doaj   +1 more source