Results 141 to 150 of about 5,456 (165)
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Towards artificial mechanosensing
Nature Materials, 2020Carbon nanotubes with single-digit diameter embedded in a solid artificial membrane show pressure-sensitive ionic conductance that is similar to the mechanically activated currents of biological ion channels.
Sanjin Marion, Aleksandra Radenovic
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Journal of Neurobiology, 2004
AbstractThe ability of cells to detect and transduce mechanical stimuli impinging on them is a fundamental process that underlies normal cell growth, hearing, balance, touch, and pain. Surprisingly, little research has focused on mechanotransduction as it relates to the sensations of somatic touch and pain.
Gary R, Lewin, Rabih, Moshourab
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AbstractThe ability of cells to detect and transduce mechanical stimuli impinging on them is a fundamental process that underlies normal cell growth, hearing, balance, touch, and pain. Surprisingly, little research has focused on mechanotransduction as it relates to the sensations of somatic touch and pain.
Gary R, Lewin, Rabih, Moshourab
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Mechanosensation and joint deformities
Science, 2023Dysfunction of a mechanosensor in sensory neurons causes joint ...
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Platelet mechanosensing axis revealed
Nature Materials, 2019An intermediate affinity state of integrin αIIBβ3 has been identified to be a key player in platelet mechanosignalling.
X Frank, Zhang, Xuanhong, Cheng
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Oncogenetic engagement with mechanosensing
Nature Materials, 2020Reprogramming normal cells into tumour precursors involves complex reconditioning of the tissue microenvironment. Cumulative integration of genetic drivers with extrinsic mechanical inputs is now shown to engage YAP/TAZ to rewire cell mechanics and initiate tumorigenic reprogramming.
Sayan Chakraborty, Wanjin Hong
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Mechanosensing in liver regeneration
Seminars in Cell & Developmental Biology, 2017Liver is highly regenerative as it can restore its function and size even after 70% partial hepatectomy. During liver regeneration, the mechanical and chemical environment of liver is altered with accumulation of various growth factors and remodeling of extracellular environment. Cells can sense the changes in their cellular environment through various
Ziwei, Song +5 more
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Comprehensive Physiology
AbstractElectrical mechanosensing is a process mediated by specialized ion channels, gated directly or indirectly by mechanical forces, which allows cells to detect and subsequently respond to mechanical stimuli. The activation of mechanosensitive (MS) ion channels, intrinsically gated by mechanical forces, or mechanoresponsive (MR) ion channels ...
John D, Tranter +3 more
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AbstractElectrical mechanosensing is a process mediated by specialized ion channels, gated directly or indirectly by mechanical forces, which allows cells to detect and subsequently respond to mechanical stimuli. The activation of mechanosensitive (MS) ion channels, intrinsically gated by mechanical forces, or mechanoresponsive (MR) ion channels ...
John D, Tranter +3 more
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TRP channels in mechanosensation
Current Opinion in Neurobiology, 2005Channels of the TRP superfamily have sensory roles in a wide variety of receptor cells, especially in mechanosensation. In some cases, the channels appear to be directly activated by mechanical force; in others, they appear to be downstream of a messenger pathway initiated by force on a non-channel sensor.
Shuh-Yow, Lin, David P, Corey
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Mechanosensing at Cellular Interfaces
Langmuir, 2018At the plasma membrane interface, cells use various adhesions to sense their extracellular environment. These adhesions facilitate the transmission of mechanical signals that dictate cell behavior. This review discusses the mechanisms by which these mechanical signals are transduced through cell-matrix and cell-cell adhesions and how this ...
Ryan J. Leiphart +4 more
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THE MOLECULES OF MECHANOSENSATION
Annual Review of Neuroscience, 1997▪ Abstract Mechanosensation, the transduction of mechanical forces into a cellular electrochemical signal, enables living organisms to detect touch; vibrations, such as sound; accelerations, including gravity; body movements; and changes in cellular volume and shape.
J, Garcia-Anoveros, D P, Corey
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