Results 31 to 40 of about 5,456 (165)

Mechanosensitive channels in lung disease

open access: yesFrontiers in Physiology, 2023
Mechanosensitive channels (MS channels) are membrane proteins capable of responding to mechanical stress over a wide dynamic range of external mechanical stimuli.
Mengning Zheng   +11 more
doaj   +1 more source

SnapShot: Mechanosensing Matrix

open access: yesCell, 2016
Cells sense and respond to properties of their microenvironment that can affect cell morphology, protein levels and localization, gene expression, and even nuclear integrity. Tissue micro-stiffness, largely influenced by extracellular matrix, varies dramatically within an organism and can be a useful parameter to both clarify and organize a wide range ...
Jerome, Irianto   +3 more
openaire   +2 more sources

Obesity, but not overweight, is associated with plantar light touch sensation in children aged 8 to 16 years: A cross‐sectional study

open access: yesObesity Science & Practice, 2020
Summary Objective Increased foot‐ground contact loading engenders adaptive glabrous skin thickening and can decrease mechanoreceptor acuity and alter plantar cutaneous sensation.
Toyin Ajisafe   +3 more
doaj   +1 more source

TRPV4—A Missing Link Between Mechanosensation and Immunity

open access: yesFrontiers in Immunology, 2020
Transient receptor potential vanilloid-type 4 (TRPV4) cation channel is widely expressed in all tissues as well as in immune cells and its function as mechanosensitive Ca2+ channel seems to be conserved throughout all mammalian species. Of late, emerging
Laura Michalick   +3 more
doaj   +1 more source

Coding of whisker motion across the mouse face

open access: yeseLife, 2019
Haptic perception synthesizes touch with proprioception, the sense of body position. Humans and mice alike experience rich active touch of the face.
Kyle S Severson   +3 more
doaj   +1 more source

State-specific morphological deformations of the lipid bilayer explain mechanosensitive gating of MscS ion channels

open access: yeseLife, 2023
The force-from-lipids hypothesis of cellular mechanosensation posits that membrane channels open and close in response to changes in the physical state of the lipid bilayer, induced for example by lateral tension. Here, we investigate the molecular basis
Yein Christina Park   +4 more
doaj   +1 more source

Proteomic Changes in the Sound Vibration-Treated Arabidopsis thaliana Facilitates Defense Response during Botrytis cinerea Infection

open access: yesThe Plant Pathology Journal, 2019
Sound vibration (SV) treatment can trigger various molecular and physiological changes in plants. Previously, we showed that pre-exposure of Arabidopsis plants to SV boosts its defense response against Botrytis cinerea fungus. The present study was aimed
Ritesh Ghosh   +5 more
doaj   +1 more source

Mechanosensation

open access: yesWormBook, 2006
Wild C. elegans and other nematodes live in dirt and eat bacteria, relying on mechanoreceptor neurons (MRNs) to detect collisions with soil particles and other animals as well as forces generated by their own movement. MRNs may also help animals detect bacterial food sources.
openaire   +3 more sources

Mechanosensing: A Regulation Sensation [PDF]

open access: yesCurrent Biology, 2015
Mechanosensing of surfaces in bacteria is a process that often uses obstruction of flagellum rotation to trigger behaviors such as adhesion and surface-associated movement. In a recent publication, the PilY1 protein of Pseudomonas aeruginosa has been implicated as a novel mechanosensor that stimulates virulence in response to surface attachment.
Ellison, Courtney, Brun, Yves V.
openaire   +2 more sources

Forces Bless You: Mechanosensitive Piezo Channels in Gastrointestinal Physiology and Pathology

open access: yesBiomolecules
The gastrointestinal (GI) tract is an organ actively involved in mechanical processes, where it detects forces via a mechanosensation mechanism. Mechanosensation relies on specialized cells termed mechanoreceptors, which convert mechanical forces into ...
Jing Guo   +8 more
doaj   +1 more source

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