Results 41 to 50 of about 5,456 (165)

Noxious Mechanosensation [PDF]

, 2018
Abstract This article introduces a number of critical features of mechanical transduction and neuronal sensory coding, with particular reference to mechanical pain. High threshold mechanoreceptors (HTMRs) in skin are the first relay point for the transduction of noxious mechanical force into the nervous system, and their properties ...
Delmas, Patrick, Korogod, Sergiy, Coste, Bertrand   +2 more
openaire   +2 more sources

Cytokinesis mechanics and mechanosensing [PDF]

Cytoskeleton, 2012
AbstractCytokinesis shape change occurs through the interfacing of three modules, cell mechanics, myosin II‐mediated contractile stress generation and sensing, and a control system of regulatory proteins, which together ensure flexibility and robustness.
Hoku, West-Foyle, Douglas N, Robinson
openaire   +2 more sources

Nonlinear mechanosensation in fiber networks

Physical Review Research
In the extracellular matrix, eukaryotic cells exert forces that deform their surroundings. By doing so, they can perform mechanosensation: Cells measure the mechanics of their environment, and adapt their behavior accordingly. Extracellular matrices are,
Estelle Berthier, Haiqian Yang, Ming Guo, Pierre Ronceray, Chase P. Broedersz   +4 more
doaj   +1 more source

A Review on Recent Trends of Bioinspired Soft Robotics: Actuators, Control Methods, Materials Selection, Sensors, Challenges, and Future Prospects

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This article reviews the current state of bioinspired soft robotics. The article discusses soft actuators, soft sensors, materials selection, and control methods used in bioinspired soft robotics. It also highlights the challenges and future prospects of this field.
Abhirup Sarker, Tamzid Ul Islam, Md. Robiul Islam   +2 more
wiley   +1 more source

Piezo channels in the intestinal tract

Frontiers in Physiology
The intestine is the largest mechanosensitive organ in the human body whose epithelial cells, smooth muscle cells, neurons and enteroendocrine cells must sense and respond to various mechanical stimuli such as motility, distension, stretch and shear to ...
Haolong He, Jingying Zhou, Xuan Xu, Pinxi Zhou, Huan Zhong, Huan Zhong, Mi Liu, Mi Liu   +7 more
doaj   +1 more source

Pericellular colocalisation and interactive properties of type VI collagen and perlecan in the intervertebral disc [PDF]

European Cells & Materials, 2016
The aim of this study was to immunolocalise type VI collagen and perlecan and determine their interactive properties in the intervertebral disc (IVD).
AJ Hayes, CC Shu, MS Lord, CB Little, JM Whitelock, J Melrose   +5 more
doaj   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

Fluorescently Labeled Gradient Hydrogels Reveal Matrix‐Dependent Cell Responses to Substrate Stiffness

Small, EarlyView.
This work demonstrates a new thermophoretic strategy to fabricate fluorescently labeled stiffness gradient hydrogels, enabling contactless stiffness characterization. Fibroblasts cultured on gradient GelMA and Gellan gum hydrogels revealed distinct cell morphology and migration behavior.
Shin Wei Chong, Li Liu, Daryan Kempe, Yingqi Zhang, Kourosh Kalantar‐Zadeh, Marcela M. M. Bilek, Lining Arnold Ju, Maté Biro, Daniele Vigolo   +8 more
wiley   +1 more source

Molecular basis for a pore block of Tentonin 3 expressed in HEK293 cells by a conopeptide, NMB‐1

British Journal of Pharmacology, EarlyView.
Background and Purpose Tentonin 3 (TTN3/TMEM150C) is a mechanosensitive ion channel that plays critical roles in mechanotransduction processes. TTN3 forms a tetramer with a predicted rectangular shape and a central pore. A conotoxin ρ‐TIA and its synthetic analog, noxious mechanosensation blocker 1 (NMB‐1), were initially developed to inhibit slowly ...
Sujin Lim, Junhyuk Woo, Sungmin Pak, Joonho Paik, Gyu‐Sang Hong, Ji Hun Wi, Sanghee Lee, Cristina Fenollar‐Ferrer, Kyungreem Han, Young Kee Shin, Uhtaek Oh   +10 more
wiley   +1 more source

Mechanosensing of substrate thickness [PDF]

Physical Review E, 2010
Structure and function of the adherent cell depend in a crucial way on its microenvironment, including the stiffness of its substrate. It is often asserted that substrate thickness (as opposed to stiffness) plays a negligible role and therefore may be considered semi-infinite.
Yu-Chun Lin, Dhananjay T. Tambe, Chan Young Park, Michael R. Wasserman, Xavier Trepat, Ramaswamy Krishnan, Guillaume Lenormand, Jeffrey J. Fredberg, James P. Butler   +8 more
openaire   +3 more sources