Results 81 to 90 of about 5,456 (165)

Ion Channel Regulation in Caveolae and Its Pathological Implications

Cells
Caveolae are distinctive, flask-shaped structures within the cell membrane that play critical roles in cellular signal transduction, ion homeostasis, and mechanosensation.
Jianyi Huo, Liangzhu Mo, Xiaojing Lv, Yun Du, Huaqian Yang   +4 more
doaj   +1 more source

TRPV4 regulates intraocular pressure through trabecular meshwork contractility and fibrosis

Channels
Intraocular pressure (IOP) is dynamically regulated by the contractility and viscoelasticity of the trabecular meshwork (TM). Two recent studies identified the polymodal cation channel TRPV4 as a central mechanosensor that integrates mechanical ...
Juš Žavbi, Sarah N. Redmon, David Križaj   +2 more
doaj   +1 more source

Epidermal cells and sensory neurons team up

eLife
Experiments in fruit fly larvae show that epidermal cells can communicate with sensory neurons to drive responses to pain.
Jean-Christophe Boivin, Tomoko Ohyama
doaj   +1 more source

Stiffness Decouples Cellular Mechanosensation [PDF]

Biophysical Journal, 2020
Vignesharavind, Subramanianbalachandar, Robert, Steward   +1 more
openaire   +2 more sources

Pharyngeal mechanosensory neurons control food swallow in Drosophila melanogaster

eLife
As the early step of food ingestion, the swallow is under rigorous sensorimotor control. Nevertheless, the mechanisms underlying swallow control at a molecular and circuitry level remain largely unknown.
Jierui Qin, Tingting Yang, Kexin Li, Ting Liu, Wei Zhang   +4 more
doaj   +1 more source

Mechanosensing alters platelet migration

Acta Biomaterialia
Platelets have long been established as a safeguard of our vascular system. Recently, haptotactic platelet migration has been discovered as a part of the immune response. In addition, platelets exhibit mechanosensing properties, changing their behavior in response to the stiffness of the underlying substrate.
Hendrik von Eysmondt, Jan Seifert, Johannes Rheinlaender, Tilman E. Schäffer   +3 more
openaire   +2 more sources

The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2

Experimental Physiology
A metabotropic glutamate receptor coupled to phospholipase D (PLD‐mGluR) was discovered in the hippocampus over three decades ago. Its pharmacology and direct linkage to PLD activation are well established and indicate it is a highly atypical glutamate ...
Karen J. Thompson, Sonia Watson, Chiara Zanato, Sergio Dall'Angelo, Joriene C. De Nooij, Bethany Pace‐Bonello, Fiona C. Shenton, Helen E. Sanger, Beverly A. Heinz, Lisa M. Broad, Noelle Grosjean, Jessica R. McQuillian, Marina Dubini, Susan Pyner, Iain Greig, Matteo Zanda, David Bleakman, Robert W. Banks, Guy S. Bewick   +18 more
doaj   +1 more source

Evolution of sensory systems underlies the emergence of predatory feeding behaviors in nematodes. [PDF]

Proc Natl Acad Sci U S A
Roca M, Göze Eren G, Böger L, Didenko O, Lo WS, Scholz M, Lightfoot JW.   +6 more
europepmc   +1 more source

Cardiac-vagal rhythm echoes on the heartbeat's mechanosensory imprint in the brain. [PDF]

Commun Biol
Candia-Rivera D, Chavez M.
europepmc   +1 more source

Programmable acoustofluidic engineering for creating gradient biomaterials. [PDF]

Sci Adv
Lu Y, He Y, Xia J, Liu M, Rich J, Jin K, Zhong R, Yang K, Qian J, Chen Y, Li K, Ma Z, Huang TJ.   +12 more
europepmc   +1 more source