Results 161 to 170 of about 9,819 (199)
Some of the next articles are maybe not open access.
THE MOLECULES OF MECHANOSENSATION
Annual Review of Neuroscience, 1997▪ Abstract  Mechanosensation, the transduction of mechanical forces into a cellular electrochemical signal, enables living organisms to detect touch; vibrations, such as sound; accelerations, including gravity; body movements; and changes in cellular volume and shape.
J, Garcia-Anoveros, D P, Corey
openaire +2 more sources
Current Opinion in Neurobiology, 2005
Because bacterial mechanosensitive channels have been cloned, purified, crystallized and subjected to a genetic, biochemical and physical scrutiny, they have become the current structural models of mechanosensation to atomic detail. The key observation, supported by recent mutagenesis studies, is that these channels receive stretch force directly ...
Andriy, Anishkin, Ching, Kung
openaire +2 more sources
Because bacterial mechanosensitive channels have been cloned, purified, crystallized and subjected to a genetic, biochemical and physical scrutiny, they have become the current structural models of mechanosensation to atomic detail. The key observation, supported by recent mutagenesis studies, is that these channels receive stretch force directly ...
Andriy, Anishkin, Ching, Kung
openaire +2 more sources
Journal of Neurobiology, 2004
AbstractThe ability of cells to detect and transduce mechanical stimuli impinging on them is a fundamental process that underlies normal cell growth, hearing, balance, touch, and pain. Surprisingly, little research has focused on mechanotransduction as it relates to the sensations of somatic touch and pain.
Gary R, Lewin, Rabih, Moshourab
openaire +2 more sources
AbstractThe ability of cells to detect and transduce mechanical stimuli impinging on them is a fundamental process that underlies normal cell growth, hearing, balance, touch, and pain. Surprisingly, little research has focused on mechanotransduction as it relates to the sensations of somatic touch and pain.
Gary R, Lewin, Rabih, Moshourab
openaire +2 more sources
Towards artificial mechanosensing
Nature Materials, 2020Carbon nanotubes with single-digit diameter embedded in a solid artificial membrane show pressure-sensitive ionic conductance that is similar to the mechanically activated currents of biological ion channels.
Sanjin Marion, Aleksandra Radenovic
openaire +4 more sources
Mechanosensation and joint deformities
Science, 2023Dysfunction of a mechanosensor in sensory neurons causes joint ...
openaire +2 more sources
Oncogenetic engagement with mechanosensing
Nature Materials, 2020Reprogramming normal cells into tumour precursors involves complex reconditioning of the tissue microenvironment. Cumulative integration of genetic drivers with extrinsic mechanical inputs is now shown to engage YAP/TAZ to rewire cell mechanics and initiate tumorigenic reprogramming.
Sayan Chakraborty, Wanjin Hong
openaire +2 more sources
Mechanosensing by Vascular Endothelium
Annual Review of PhysiologyMechanical forces influence different cell types in our bodies. Among the earliest forces experienced in mammals is blood movement in the vascular system. Blood flow starts at the embryonic stage and ceases when the heart stops. Blood flow exposes endothelial cells (ECs) that line all blood vessels to hemodynamic forces.
Xin Rui Lim, Osama Harraz
exaly +3 more sources
Mechanosensing at Cellular Interfaces
Langmuir, 2018At the plasma membrane interface, cells use various adhesions to sense their extracellular environment. These adhesions facilitate the transmission of mechanical signals that dictate cell behavior. This review discusses the mechanisms by which these mechanical signals are transduced through cell-matrix and cell-cell adhesions and how this ...
Ryan J. Leiphart +4 more
openaire +2 more sources
TRP channels in mechanosensation
Current Opinion in Neurobiology, 2005Channels of the TRP superfamily have sensory roles in a wide variety of receptor cells, especially in mechanosensation. In some cases, the channels appear to be directly activated by mechanical force; in others, they appear to be downstream of a messenger pathway initiated by force on a non-channel sensor.
Shuh-Yow, Lin, David P, Corey
openaire +2 more sources
Mechanosensing in liver regeneration
Seminars in Cell & Developmental Biology, 2017Liver is highly regenerative as it can restore its function and size even after 70% partial hepatectomy. During liver regeneration, the mechanical and chemical environment of liver is altered with accumulation of various growth factors and remodeling of extracellular environment. Cells can sense the changes in their cellular environment through various
Ziwei, Song +5 more
openaire +2 more sources