Results 181 to 190 of about 36,721 (301)

Exercise Alleviates Osteoporosis and Hyperglycemia in Type 1 Diabetes Mellitus Mice via Piezo1-Mediated Mechanotransduction. [PDF]

Biology (Basel)
Cao M, Pang F, Yu Y, Yu J, Ma S, Sun L, Fan X, Tang L.   +7 more
europepmc   +1 more source

Advances in GPCRs Associated With Wnt Signaling Within the Auditory System

Medicine Bulletin, EarlyView.
ABSTRACT G protein‐coupled receptors (GPCRs) that interact with the Wnt signaling pathway are pivotal for auditory system homeostasis, as they orchestrate inner ear development, hair cell (HC) regeneration, and hearing preservation. Frizzled (FZD) receptors, the core Wnt‐related GPCRs, bind Wnt ligands and co‐receptors (e.g., LRP5/6) to activate both ...
Liang Wang, Changling Xu, Jiangang Fan, Renjie Chai   +3 more
wiley   +1 more source

Matrix Stiffness Drives Aggressive Phenotype in Tongue Squamous Cell Carcinoma via Mechanotransduction-Stromal Signalling. [PDF]

Int Dent J
Tiskratok W, Kyawsoewin M, Thuephut R, Ketkrathok K, Leerahakanch C, Chanwises P, Jitprasertwong P, Yamada M, Egusa H, Limraksasin P.   +9 more
europepmc   +1 more source

Research status and trends of Piezo1 and brain: A bibliometric analysis

Neuroprotection, EarlyView.
This graphical abstract illustrates the workflow and key findings of the bibliometric analysis of Piezo1 in brain research. The primary results were visually centered on a brain graphic highlighting the Piezo1 channel, and three converging research hotspots were identified: neurovascular regulation, calcium signaling, and neuroinflammation.
Yu Liu, Shengzhen Luo, Hao Zhang, Jianqing Lin, Hui Xiao, Yuying Ma, Dongxue Ye, Liang Cong, Yongwang Li   +8 more
wiley   +1 more source

Mechanotransduction and its impact on regenerative medicine in orthopedic rehabilitation (Review). [PDF]

Int J Mol Med
Wang B, Zeng X, Liu H, Li L, Lei T, Li Y, Fang Q, Cao Y, Dong B.   +8 more
europepmc   +1 more source

The mechano-immune-vesicle regulatory circuit: a systems framework for bone homeostasis and regeneration. [PDF]

Bioact Mater
Yang T, Dong Z, Chen L, Kou X.
europepmc   +1 more source

Jervell and Lange‐Nielsen Syndrome Related Clinical Genetics and Experimental Models

Pediatric Discovery, EarlyView.
ABSTRACT Jervell and Lange‐Nielsen syndrome (JLNS) is defined by electrocardiographic QT prolongation and sensorineural hearing loss, caused by homozygous or compound heterozygous variants in KCNQ1 and/or KCNE1. KCNQ1 encodes the alpha subunit Kv7.1 of the ion channels accountable for slow delayed rectifier potassium currents (IKs), whereas KCNE1 ...
Yafei Zhou, Christopher L.‐H. Huang, Ying Yang, Yanmin Zhang   +3 more
wiley   +1 more source

Rehabilitation and return to activity after platelet‐rich plasma injections in chronic tendinopathies: Consensus from international experts

PM&R, EarlyView.
Abstract Background The effectiveness of platelet‐rich plasma (PRP) injections in chronic tendinopathies remains debated. Although the product's characteristics play a role, the impact of postinjection recommendations remains poorly investigated. Objective To establish principles and guidelines for post‐PRP injection rehabilitation and return to ...
Vincent Gremeaux, Martin Lamontagne, Valérie Bélanger, Etienne Dalmais, Eric Noël, Alain Frey, Paul Ornetti, Fadoua Allali, Jimmy Gross, F. Michel, Hervé Bard, Jean‐François Kaux, the GRIIP (Groupe de Recherche International sur les Injections de Plaquettes; International Research Group on Platelet Injections)   +12 more
wiley   +1 more source

A Mechano-Feedback Loop Orchestrated by SUN1/2 Governs Cellular Mechanoadaptation via Lamina-Associated Domain Remodeling. [PDF]

Research (Wash D C)
Xie Y, Zuo Z, Lu C, Zhao Y, Guo L, Xu W, Liu F, Guidoin R, Zhang H, Qiu J, Wang G, Peng Q.   +11 more
europepmc   +1 more source

Engineering Nanoscale Frontiers: Valve Metal Oxide Nanostructures From Fundamentals to Multifunctional Biomedical Applications

The Chemical Record, EarlyView.
Valve metal oxide nanostructures such as TiO2, Ta2O5, Nb2O5, ZrO2, and HfO2 are emerging as versatile biomedical platforms due to their tunable surface properties, exceptional stability, and inherent biocompatibility. This review highlights their synthesis, physicochemical properties, and biological interactions, addressing their roles in advanced ...
Nina Kummer, Désirée Gül, İdris Sargin, Mustafa Dolaz, Dzmitry Shcharbin, Shirley K. Knauer, Burcu Önal Acet, Emrah Dikici, Mingyuan Gao, Mehmet Odabaşı, Ömür Acet, Roland H. Stauber   +11 more
wiley   +1 more source