Results 201 to 210 of about 36,721 (301)

Bone tissue regeneration: role of osteocyte mechanosensing and mechanotransduction. [PDF]

Stem Cells Transl Med
Seddiqi H, Klein-Nulend J, Jin J.
europepmc   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

KDM6B safeguards mineralized tissue homeostasis from mechanical stress through epigenetic control of PIEZO1-mediated mechanotransduction in the mouse incisor. [PDF]

Bone Res
Meng L, Zhang M, Feng J, Guo T, Hekmat H, Ziaei H, Chen P, Harouni A, Ho TV, Chai Y.   +9 more
europepmc   +1 more source

A noncanonical role for Jagged1 in endothelial mechanotransduction

The FEBS Journal, EarlyView.
This study reveals a noncanonical role for Jagged1 in endothelial mechanotransduction. Shear stress modulates Jagged1 expression and subcellular localization. Loss of Jagged1 attenuates mechanotransduction and reduces Src, VEGFR2, and ERK signaling. Direct mechanical stimulation of Jagged1 induces activation of these signaling pathways.
Freddy Suarez Rodriguez, Noora Virtanen, Elmeri Kiviluoto, Rob C. H. Driessen, Feihu Zhao, Carlijn V. C. Bouten, Oscar M. J. A. Stassen, Cecilia M. Sahlgren   +7 more
wiley   +1 more source

Biomechanical regulation of stem cells: Implications for cell therapeutics. [PDF]

iScience
Chen A, Harris C, Yoo E, Qu CK.
europepmc   +1 more source

Polycystins and mechanotransduction in bone

Oncotarget, 2017
Gargalionis, A.N., Basdra, E.K., Papavassiliou, A.G.   +2 more
openaire   +3 more sources

Simultaneous tibial and fibular sesamoid bone stress injuries in a collegiate volleyball player: The role of shockwave therapy in recovery and return to sport

PM&R, EarlyView.
Bridget M. Doyle, Nader F. Elkabbani, Farah Hussain, Mason W. Briles, Rosa M. Pasculli   +4 more
wiley   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Calcium Hydroxylapatite Injection Improves Senile Purpura via YAP-Mediated Mechanotransduction. [PDF]

Int J Dermatol
Seo J, Kim H, Goo BL, Park JY, Rho NK, Lee S.   +5 more
europepmc   +1 more source

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

The FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka, Matija Hrovatin, Bor Bokalj, Boris Turk   +3 more
wiley   +1 more source